4DX1
Crystal structure of the human TRPV4 ankyrin repeat domain
Summary for 4DX1
Entry DOI | 10.2210/pdb4dx1/pdb |
Related | 4DX2 |
Descriptor | Transient receptor potential cation channel subfamily V member 4, PHOSPHATE ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | ankyrin repeat, ion channel, menbrane, transport protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Multi-pass membrane protein (By similarity). Isoform 1: Cell membrane. Isoform 5: Cell membrane: Q9HBA0 |
Total number of polymer chains | 2 |
Total formula weight | 59480.44 |
Authors | Inada, H.,Gaudet, R. (deposition date: 2012-02-27, release date: 2012-07-18, Last modification date: 2024-02-28) |
Primary citation | Inada, H.,Procko, E.,Sotomayor, M.,Gaudet, R. Structural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel. Biochemistry, 51:6195-6206, 2012 Cited by PubMed: 22702953DOI: 10.1021/bi300279b PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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