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2H1L
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The Structure of the Oncoprotein SV40 Large T Antigen and p53 Tumor Suppressor Complex
分子名称: Cellular tumor antigen p53, Large T antigen, ZINC ION
著者Lilyestrom, W, Klein, M.G, Chen, X.S.
登録日2006-05-16
公開日2006-09-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor.
Genes Dev., 20, 2006
8G9B
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Human IMPDH2 mutant - L245P, treated with GTP, ATP, IMP, and NAD+; compressed filament segment reconstruction
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ...
著者O'Neill, A.G, Kollman, J.M.
登録日2023-02-21
公開日2023-04-19
最終更新日2023-08-09
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
8G0K
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Bacteroides multispecies type VI secretion system Ntox15 domain effector and immunity Tde1/Tdi1
分子名称: DUF1851 domain-containing protein, Ntox15 domain-containing protein
著者Bosch, D.E, Mougous, J.D.
登録日2023-01-31
公開日2023-07-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural disruption of Ntox15 nuclease effector domains by immunity proteins protects against type VI secretion system intoxication in Bacteroidales.
Mbio, 14, 2023
8FC8
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Cryo-EM structure of the human TRPV4 in complex with GSK1016790A
分子名称: CHOLESTEROL HEMISUCCINATE, N-[(2S)-1-{4-[N-(2,4-dichlorobenzene-1-sulfonyl)-L-seryl]piperazin-1-yl}-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide, Transient receptor potential cation channel subfamily V member 4
著者Kwon, D.H, Lee, S.-Y, Zhang, F.
登録日2022-12-01
公開日2023-07-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease.
Nat Commun, 14, 2023
8FCB
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Cryo-EM structure of the human TRPV4 - RhoA in complex with GSK1016790A
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, CHOLESTEROL HEMISUCCINATE, N-[(2S)-1-{4-[N-(2,4-dichlorobenzene-1-sulfonyl)-L-seryl]piperazin-1-yl}-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide, ...
著者Kwon, D.H, Lee, S.-Y, Zhang, F.
登録日2022-12-01
公開日2023-07-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease.
Nat Commun, 14, 2023
7Y7P
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QDE-1 in complex with RNA template, RNA primer and AMPNPP
分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Cui, R.X, Gan, J.H, Ma, J.B.
登録日2022-06-22
公開日2022-09-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1.
Nucleic Acids Res., 50, 2022
6ND0
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human BK channel reconstituted into liposomes
分子名称: Calcium-activated potassium channel subunit alpha-1
著者Wang, L, Tonggu, L.
登録日2018-12-13
公開日2020-06-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Broken symmetry in the human BK channel
To Be Published
7Y7Q
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QDE-1 in complex with RNA template, RNA primer and 3'-dGTP
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Cui, R.X, Gan, J.H, Ma, J.B.
登録日2022-06-22
公開日2022-09-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1.
Nucleic Acids Res., 50, 2022
7Y7R
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QDE-1 in complex with DNA template, RNA primer and 3'-dGTP
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*GP*AP*AP*CP*TP*AP*CP*CP*GP*TP*CP*GP*GP*A)-3'), ...
著者Cui, R.X, Gan, J.H, Ma, J.B.
登録日2022-06-22
公開日2022-09-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1.
Nucleic Acids Res., 50, 2022
7Y4P
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Human Plexin A1, extracellular domains 1-4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A1
著者Tanaka, T, Neyazaki, M, Nogi, T.
登録日2022-06-15
公開日2022-10-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Hybrid in vitro/in silico analysis of low-affinity protein-protein interactions that regulate signal transduction by Sema6D.
Protein Sci., 31, 2022
7Y7S
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QDE-1 in complex with DNA template, RNA primer and AMPNPP
分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Cui, R.X, Gan, J.H, Ma, J.B.
登録日2022-06-22
公開日2022-09-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1.
Nucleic Acids Res., 50, 2022
6BI7
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BU of 6bi7 by Molmil
Crystal structure of Rev7-WT/Rev3 as a monomer under high-salt conditions
分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
著者Rizzo, A.A, Korzhnev, D.M, Hao, B, Li, Y.
登録日2017-11-01
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1KAW
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BU of 1kaw by Molmil
STRUCTURE OF SINGLE STRANDED DNA BINDING PROTEIN (SSB)
分子名称: SINGLE-STRANDED DNA BINDING PROTEIN
著者Raghunathan, S, Waksman, G.
登録日1996-12-06
公開日1997-12-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the homo-tetrameric DNA binding domain of Escherichia coli single-stranded DNA-binding protein determined by multiwavelength x-ray diffraction on the selenomethionyl protein at 2.9-A resolution.
Proc.Natl.Acad.Sci.USA, 94, 1997
8FCA
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BU of 8fca by Molmil
Cryo-EM structure of the human TRPV4 - RhoA in complex with 4alpha-Phorbol 12,13-didecanoate
分子名称: (1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-9a-(decanoyloxy)-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl decanoate, CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily V member 4
著者Kwon, D.H, Lee, S.-Y, Zhang, F.
登録日2022-12-01
公開日2023-07-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease.
Nat Commun, 14, 2023
2IHO
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Crystal structure of MOA, a lectin from the mushroom Marasmius oreades in complex with the trisaccharide Gal(1,3)Gal(1,4)GlcNAc
分子名称: Lectin, beta-D-galactopyranose-(1-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Grahn, E, Askarieh, G, Holmner, A, Tateno, H, Winter, H.C, Goldstein, I.J, Krengel, U.
登録日2006-09-27
公開日2007-05-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Crystal structure of the marasmius oreades mushroom lectin in complex with a xenotransplantation epitope.
J.Mol.Biol., 369, 2007
6O19
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BU of 6o19 by Molmil
Crystal Structure of Pho7 complex with pho1 promoter site 2
分子名称: DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*AP*TP*TP*TP*CP*CP*GP*AP*AP*TP*AP*AP*T)-3'), DNA (5'-D(*TP*TP*AP*TP*TP*CP*GP*GP*AP*AP*AP*TP*TP*AP*AP*AP*AP*AP*CP*A)-3'), Transcription factor Pho7, ...
著者Garg, A, Goldgur, Y, Shuman, S.
登録日2019-02-18
公開日2019-04-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.596 Å)
主引用文献Structure of Fission Yeast Transcription Factor Pho7 Bound topho1Promoter DNA and Effect of Pho7 Mutations on DNA Binding and Phosphate Homeostasis.
Mol.Cell.Biol., 39, 2019
6U6R
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Solution NMR Structure Of The delta30-ngMinE Protein From Neisseria gonorrheae
分子名称: Cell division topological specificity factor
著者Cai, M, Shen, Y, Clore, M.
登録日2019-08-30
公開日2020-07-08
最終更新日2024-05-01
実験手法SOLID-STATE NMR
主引用文献Probing transient excited states of the bacterial cell division regulator MinE by relaxation dispersion NMR spectroscopy.
Proc.Natl.Acad.Sci.USA, 116, 2019
2IIF
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BU of 2iif by Molmil
single chain Integration Host Factor mutant protein (scIHF2-K45aE) in complex with DNA
分子名称: DNA (5'-D(*DGP*DCP*DTP*DTP*DAP*DTP*DCP*DAP*DAP*DTP*DTP*DTP*DGP*DTP*DTP*DGP*DCP*DAP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DCP*DAP*DAP*DAP*DAP*DAP*DAP*DGP*DCP*DAP*DTP*DT)-3'), Integration host factor, ...
著者Bao, Q, Droege, P, Davey, C.A.
登録日2006-09-28
公開日2007-02-20
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献A Divalent Metal-mediated Switch Controlling Protein-induced DNA Bending
J.Mol.Biol., 367, 2007
2INU
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BU of 2inu by Molmil
Crystal structure of Inulin fructotransferase in the absence of substrate
分子名称: Inulin fructotransferase, PHOSPHONATE
著者Rhee, S, Jung, W.S.
登録日2006-10-09
公開日2006-12-26
最終更新日2020-10-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and functional insights into intramolecular fructosyl transfer by Inulin fructotransferase
J.Biol.Chem., 282, 2007
6U6P
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Solution NMR Structure Of The Full Length Latent Form MinE Protein From Neisseria gonorrheae
分子名称: Cell division topological specificity factor
著者Cai, M, Shen, Y, Clore, M.
登録日2019-08-30
公開日2020-07-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Probing transient excited states of the bacterial cell division regulator MinE by relaxation dispersion NMR spectroscopy.
Proc.Natl.Acad.Sci.USA, 116, 2019
7WR4
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BU of 7wr4 by Molmil
Crystal structure of OspC3-calmodulin-caspase-4 complex
分子名称: Calmodulin-1, Caspase-4, OspC3
著者Hou, Y.J, Zeng, H, Shao, F, Ding, J.
登録日2022-01-26
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis.
Nat.Struct.Mol.Biol., 30, 2023
1L9W
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CRYSTAL STRUCTURE OF 3-DEHYDROQUINASE FROM SALMONELLA TYPHI COMPLEXED WITH REACTION PRODUCT
分子名称: 3-AMINO-4,5-DIHYDROXY-CYCLOHEX-1-ENECARBOXYLATE, 3-dehydroquinate dehydratase aroD
著者Lee, W.H, Perles, L.A, Nagem, R.A.P, Shrive, A.K, Hawkins, A, Sawyer, L, Polikarpov, I.
登録日2002-03-26
公開日2003-03-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Comparison of different crystal forms of 3-dehydroquinase from Salmonella typhi and its implication for the enzyme activity.
Acta Crystallogr.,Sect.D, 58, 2002
7M1S
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Crystal structure of human guanylate-binding protein 2 (hGBP2) K51A mutant
分子名称: Guanylate-binding protein 2, PHOSPHATE ION
著者Roy, S, Wang, B, Tian, Y, Yin, Q.
登録日2021-03-15
公開日2022-04-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Crystal structure of human guanylate-binding protein 2 (hGBP2) K51A mutant
To Be Published
6U6S
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Solution NMR Structure Of The I24N-delta10-ngMinE Protein From Neisseria gonorrheae
分子名称: Cell division topological specificity factor
著者Cai, M, Shen, Y, Clore, M.
登録日2019-08-30
公開日2020-07-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Probing transient excited states of the bacterial cell division regulator MinE by relaxation dispersion NMR spectroscopy.
Proc.Natl.Acad.Sci.USA, 116, 2019
7C0P
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Structure of proteinase K obtained in SSRF using serial crystallography
分子名称: CALCIUM ION, Proteinase K
著者Zhao, F.Z.
登録日2020-05-01
公開日2020-12-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A novel sample delivery system based on circular motion for in situ serial synchrotron crystallography.
Lab Chip, 20, 2020

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