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8QHD
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Hantaan virus polymerase in hexameric state
分子名称: RNA-directed RNA polymerase L
著者Durieux Trouilleton, Q, Arragain, B, Malet, H.
登録日2023-09-07
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural characterization of the oligomerization of full-length Hantaan virus polymerase into symmetric dimers and hexamers.
Nat Commun, 15, 2024
8QGT
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5'vRNA-bound Hantaan virus polymerase in monomeric intermediate state
分子名称: RNA (5'-R(P*UP*AP*GP*UP*AP*GP*UP*AP*GP*AP*CP*A)-3'), RNA-directed RNA polymerase L
著者Durieux Trouilleton, Q, Arragain, B, Malet, H.
登録日2023-09-05
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural characterization of the oligomerization of full-length Hantaan virus polymerase into symmetric dimers and hexamers.
Nat Commun, 15, 2024
8QE5
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Apo Hantaan virus polymerase in monomeric state
分子名称: RNA-directed RNA polymerase L
著者Durieux Trouilleton, Q, Arragain, B, Malet, H.
登録日2023-08-30
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural characterization of the oligomerization of full-length Hantaan virus polymerase into symmetric dimers and hexamers.
Nat Commun, 15, 2024
8QGU
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Apo Hantaan virus polymerase in dimeric state
分子名称: RNA-directed RNA polymerase L
著者Durieux Trouilleton, Q, Arragain, B, Malet, H.
登録日2023-09-05
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structural characterization of the oligomerization of full-length Hantaan virus polymerase into symmetric dimers and hexamers.
Nat Commun, 15, 2024
5M1S
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BU of 5m1s by Molmil
Cryo-EM structure of the E. coli replicative DNA polymerase-clamp-exonuclase-theta complex bound to DNA in the editing mode
分子名称: DNA Primer Strand, DNA Template Strand, DNA polymerase III subunit alpha, ...
著者Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H.
登録日2016-10-10
公開日2017-01-18
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献Self-correcting mismatches during high-fidelity DNA replication.
Nat. Struct. Mol. Biol., 24, 2017
3JA5
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BU of 3ja5 by Molmil
Genome and RdRp structure within the capsid of no-transcribing cypovirus
分子名称: RNA-dependent RNA polymerase
著者Liu, H, Cheng, L.
登録日2015-04-21
公開日2015-10-28
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (12 Å)
主引用文献Cryo-EM shows the polymerase structures and a nonspooled genome within a dsRNA virus.
Science, 349, 2015
4CHC
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BU of 4chc by Molmil
Crystal structure of the N-terminal domain of the PA subunit of Thogoto virus polymerase (form 2)
分子名称: POLYMERASE ACIDIC PROTEIN
著者Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S.
登録日2013-12-01
公開日2014-02-05
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
4CHD
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BU of 4chd by Molmil
Crystal structure of the '627' domain of the PB2 subunit of Thogoto virus polymerase
分子名称: POLYMERASE ACIDIC PROTEIN
著者Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S.
登録日2013-12-01
公開日2014-02-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
4CGX
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BU of 4cgx by Molmil
Crystal structure of the N-terminal domain of the PA subunit of Thogoto virus polymerase (form 1)
分子名称: POLYMERASE ACIDIC PROTEIN
著者Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S.
登録日2013-11-27
公開日2014-02-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
4CHF
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BU of 4chf by Molmil
Crystal structure of the putative cap-binding domain of the PB2 subunit of Thogoto virus polymerase (form 2)
分子名称: POLYMERASE BASIC PROTEIN 2
著者Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S.
登録日2013-12-01
公開日2014-02-05
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
4CHE
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BU of 4che by Molmil
Crystal structure of the putative cap-binding domain of the PB2 subunit of Thogoto virus polymerase
分子名称: POLYMERASE BASIC PROTEIN 2
著者Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S.
登録日2013-12-01
公開日2014-02-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
5XOX
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BU of 5xox by Molmil
Crystal structure of tRNA(His) guanylyltranserase from Saccharomyces cerevisiae
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Lee, K, Lee, E.H, Son, J, Hwang, K.Y.
登録日2017-05-31
公開日2017-07-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of tRNA(His) guanylyltransferase from Saccharomyces cerevisiae
Biochem. Biophys. Res. Commun., 490, 2017
2X1A
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BU of 2x1a by Molmil
Structure of Rna15 RRM with RNA bound (G)
分子名称: 5'-R(*GP*UP*UP*GP*UP)-3', MAGNESIUM ION, MRNA 3'-END-PROCESSING PROTEIN RNA15
著者Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A.
登録日2010-01-06
公開日2010-02-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors.
Nucleic Acids Res., 38, 2010
8CI5
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BU of 8ci5 by Molmil
Structure of the SNV L protein bound to 5' RNA
分子名称: RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*GP*AP*CP*U)-3'), RNA-directed RNA polymerase L
著者Meier, K, Thorkelsson, S.R, Durieux Trouilleton, Q, Vogel, D, Yu, D, Kosinski, J, Cusack, S, Malet, H, Grunewald, K, Quemin, E.R.J, Rosenthal, M.
登録日2023-02-08
公開日2023-07-19
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural and functional characterization of the Sin Nombre virus L protein.
Plos Pathog., 19, 2023
2X1F
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BU of 2x1f by Molmil
Structure of Rna15 RRM with bound RNA (GU)
分子名称: 5'-R(*GP*UP*UP*GP*UP)-3', MRNA 3'-END-PROCESSING PROTEIN RNA15
著者Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A.
登録日2010-01-06
公開日2010-02-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors.
Nucleic Acids Res., 38, 2010
3JSB
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BU of 3jsb by Molmil
Crystal structure of the N-terminal domain of the Lymphocytic Choriomeningitis Virus L protein
分子名称: RNA-directed RNA polymerase
著者Morin, B, Jamal, S, Ferron, F.P, Coutard, B, Bricogne, G, Canard, B, Vonrhein, C, Marseilles Structural Genomics Program @ AFMB (MSGP)
登録日2009-09-10
公開日2010-09-15
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription
Plos Pathog., 6, 2010
3GSZ
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BU of 3gsz by Molmil
Structure of the genotype 2B HCV polymerase
分子名称: RNA-directed RNA polymerase
著者Rydberg, E.H, Carfi, A.
登録日2009-03-27
公開日2009-07-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for resistance of the genotype 2b hepatitis C virus NS5B polymerase to site A non-nucleoside inhibitors.
J.Mol.Biol., 390, 2009
3P9Y
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BU of 3p9y by Molmil
Crystal structure of the Drosophila melanogaster Ssu72-pCTD complex
分子名称: CG14216, IMIDAZOLE, TETRAETHYLENE GLYCOL, ...
著者Werner-Allen, J.W, Zhou, P.
登録日2010-10-18
公開日2010-12-15
最終更新日2016-08-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献cis-Proline-mediated Ser(P)5 Dephosphorylation by the RNA Polymerase II C-terminal Domain Phosphatase Ssu72.
J.Biol.Chem., 286, 2011
2R7Q
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BU of 2r7q by Molmil
Crystal Structure of VP1 apoenzyme of Rotavirus SA11 (C-terminal hexahistidine-tagged)
分子名称: RNA-dependent RNA polymerase
著者Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L.
登録日2007-09-09
公開日2008-07-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
2R7O
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BU of 2r7o by Molmil
Crystal Structure of VP1 apoenzyme of Rotavirus SA11 (N-terminal hexahistidine-tagged)
分子名称: RNA-dependent RNA polymerase
著者Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L.
登録日2007-09-09
公開日2008-07-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
6Q99
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BU of 6q99 by Molmil
Ande virus L protein N-terminus mutant K124A
分子名称: GLYCEROL, MANGANESE (III) ION, RNA polymerase
著者Fernandez-Garcia, Y, Holm, T, Kirchmair, J, Wurr, S, Gunther, S, Reindl, S.
登録日2018-12-17
公開日2020-01-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.951 Å)
主引用文献Specific inhibition of a diverse set of segmented negative strand viruses by a single molecule
To Be Published
4NJ5
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BU of 4nj5 by Molmil
Crystal structure of SUVH9
分子名称: Probable histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH9, ZINC ION
著者Du, J, Patel, D.J.
登録日2013-11-08
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation.
Nature, 507, 2014
1ESH
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BU of 1esh by Molmil
THE SOLUTION STRUCTURE OF THE STEM LOOP C 5'AUA3' TRILOOP OF BROME MOSAIC VIRUS (+) STRAND RNA
分子名称: RNA (5'-R(*GP*GP*UP*GP*CP*AP*UP*AP*GP*CP*AP*CP*C)-3')
著者Kim, C.-H, Kao, C.C, Tinoco Jr, I.
登録日2000-04-10
公開日2000-04-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献RNA motifs that determine specificity between a viral replicase and its promoter.
Nat.Struct.Biol., 7, 2000
8B8A
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BU of 8b8a by Molmil
Multimerization domain of borna disease virus 1 phosphoprotein
分子名称: Phosphoprotein
著者Tarbouriech, N, Legrand, P, Bourhis, J.M, Chenavier, F, Freslon, L, Kawasaki, J, Horie, M, Tomonaga, K, Bachiri, K, Coyaud, E, Gonzalez-Dunia, D, Ruigrok, R.W.H, Crepin, T.
登録日2022-10-04
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing.
Viruses, 14, 2022
6E53
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Structure of TERT in complex with a novel telomerase inhibitor
分子名称: MAGNESIUM ION, RNA/DNA hairpin, Telomerase reverse transcriptase, ...
著者Hernandez-Sanchez, W, Huang, W, Plucinsky, B, Garcia-Vazquez, N, Berdis, A.J, Skordalakes, E, Taylor, D.J.
登録日2018-07-19
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity.
Plos Biol., 17, 2019

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