PDB: 2940 件ウェブページステータス検索Chemie searchBIRD

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6HBY	HLA class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope 分子名称: 1,2-ETHANEDIOL, ARRPPLAELAALNLSGSRL 5T4 tumour epitope, HLA class II histocompatibility antigen, ... 著者 MacLachlan, B, Rizkallah, P.J, Sewell, A.K, Cole, D.K, Godkin, A.J. 登録日 2018-08-13 公開日 2019-08-14 最終更新日 2020-01-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope. J.Biol.Chem., 294, 2019
7EJL	Complex Structure of HLA-A*2402 with the Peptide from HCoV(CoV-2) spike protein 分子名称: 9-mer peptide from the HCoV spike protein, Beta-2-microglobulin, MHC class I antigen 著者 Murayama, K, Kato-Murayama, M, Shirouzu, M. 登録日 2021-04-02 公開日 2022-01-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Identification of TCR repertoires in functionally competent cytotoxic T cells cross-reactive to SARS-CoV-2. Commun Biol, 4, 2021
7DZN	Crystal Structure of the cross-restricted T18A TCR and HLAB4201 bound to HIV-1 Gag TL9 peptide 分子名称: Beta-2-microglobulin, Gag-Pol polyprotein, MHC class I antigen, ... 著者 Liu, Y, Yin, L. 登録日 2021-01-25 公開日 2022-01-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Cross-reactive TCR with alloreactivity for immunodominant HIV-1 epitope Gag TL9 with enhanced control of viral infection Biorxiv, 2021
7EJN	Complex Structure of HLA-A*2402 with the Peptide from HCoV(CoV-HKU1) spike protein 分子名称: 9-mer peptide from the HCoV spike protein, Beta-2-microglobulin, MHC class I antigen 著者 Murayama, K, Kato-Murayama, M, Shirouzu, M. 登録日 2021-04-02 公開日 2022-01-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Identification of TCR repertoires in functionally competent cytotoxic T cells cross-reactive to SARS-CoV-2. Commun Biol, 4, 2021
6JTP	Crystal structure of HLA-C08 in complex with a tumor mut9m peptide 分子名称: 9-mer peptide, Beta-2-microglobulin, HLA class I antigen, ... 著者 Bai, P, Zhou, Q, Wei, P, Lei, Y. 登録日 2019-04-11 公開日 2020-04-15 最終更新日 2021-02-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy. Oncoimmunology, 10, 2021
7EJM	Complex Structure of HLA-A*2402 with the Peptide from HCoV(CoV-229E) spike protein 分子名称: 9-mer peptide from the HCoV spike protein, Beta-2-microglobulin, MHC class I antigen 著者 Murayama, K, Kato-Murayama, M, Shirouzu, M. 登録日 2021-04-02 公開日 2022-01-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Identification of TCR repertoires in functionally competent cytotoxic T cells cross-reactive to SARS-CoV-2. Commun Biol, 4, 2021
7DUU	Crystal structure of HLA molecule with an KIR receptor 分子名称: Beta-2-microglobulin, Killer cell immunoglobulin-like receptor 2DS2, LEU-ASN-PRO-SER-VAL-ALA-ALA-THR-LEU, ... 著者 Yang, Y, Yin, L. 登録日 2021-01-11 公開日 2022-02-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Activating receptor KIR2DS2 bound to HLA-C1 reveals the novel recognition features of activating receptor. Immunology, 165, 2022
7DZM	Crystal Structure of the cross-restricted T18A TCR and HLAB8101 bound to HIV-1 Gag TL9 peptide 分子名称: Beta-2-microglobulin, Gag-Pol polyprotein, MHC class I antigen, ... 著者 Liu, Y, Yin, L. 登録日 2021-01-25 公開日 2022-01-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Cross-reactive TCR with alloreactivity for immunodominant HIV-1 epitope Gag TL9 with enhanced control of viral infection Biorxiv, 2021
8DVG	Structure of KRAS WT(7-16)-HLA-A*03:01 分子名称: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, HLA class I histocompatibility antigen, ... 著者 Wright, K.M, Miller, M, Gabelli, S.B. 登録日 2022-07-28 公開日 2023-07-19 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.594 Å) 主引用文献 Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen. Nat Commun, 14, 2023
8EC5	Structures of HLA-B8E76C loaded with long peptides reveal novel features at the N-terminus of the groove 分子名称: Beta-2-microglobulin, MHC class I antigen, peptide RARARARARARAFVKKKYCL 著者 Li, L, Bouvier, M. 登録日 2022-09-01 公開日 2023-07-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing. Nat Commun, 14, 2023
8DNT	SARS-CoV-2 specific T cell receptor 分子名称: Beta-2-microglobulin, MHC class I antigen alpha chain, Nucleoprotein, ... 著者 Gallagher, D.T, Wu, D, Gowthaman, R, Pierce, B.G, Mariuzza, R.A, Weng, N.P. 登録日 2022-07-11 公開日 2023-07-19 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.18 Å) 主引用文献 SARS-CoV-2 infection establishes a stable and age-independent CD8 + T cell response against a dominant nucleocapsid epitope using restricted T cell receptors. Nat Commun, 14, 2023
8E13	Structures of HLA-B8E76C loaded with long peptides reveal novel features at the N-terminus of the groove 分子名称: Beta-2-microglobulin, MHC class I antigen, PHE-ALA-LYS-LYS-LYS-TYR-CYS-LEU 著者 Li, L, Bouvier, M. 登録日 2022-08-09 公開日 2023-07-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing. Nat Commun, 14, 2023
8E8I	Structures of HLA-B8E76C loaded with long peptides reveal novel features at the N-terminus of the groove 分子名称: Beta-2-microglobulin, MHC class I antigen, PHE-VAL-LYS-LYS-LYS-TYR-CYS-LEU 著者 Li, L, Bouvier, M. 登録日 2022-08-25 公開日 2023-07-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing. Nat Commun, 14, 2023
6G3J	MHC A02 Allele presenting MTSAIGILVP 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... 著者 Rizkallah, P.J, Sewell, A.K. 登録日 2018-03-26 公開日 2019-02-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Peptide Super-Agonist Enhances T-Cell Responses to Melanoma. Front Immunol, 10, 2019
8E2Z	Structures of HLA-B8E76C loaded with long peptides reveal novel features at the N-terminus of the groove 分子名称: ALA-PHE-ALA-LYS-LYS-LYS-TYR-CYS-LEU, Beta-2-microglobulin, MHC class I protein (Fragment) 著者 Li, L, Bouvier, M. 登録日 2022-08-16 公開日 2023-08-02 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing. Nat Commun, 14, 2023
6G9Q	Ternary complex of P14 TCR with murine MHC class I H-2 Db in complex with self-antigen derived from dopamine monooxygenase. 分子名称: Beta-2-microglobulin, Dopamine beta-hydroxylase, GLYCEROL, ... 著者 Achour, A, Sandalova, T, Allerbring, E. 登録日 2018-04-11 公開日 2019-04-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Structural basis for CD8+ T cells auto-reactivity in LCMV infection to be published
6H6H	Crystal structures of the murine class I major histocompatibility complex H-2Dbm13 in complex with adenovirus-derived peptide Ad10 分子名称: Beta-2-microglobulin, GLYCEROL, H-2D cell surface glycoprotein, ... 著者 Achour, A, Sandalova, T, Han, X. 登録日 2018-07-27 公開日 2019-08-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structures of H-2Db and H-2Dbm13 with cancer-associated Ad 10 peptide reveal that subtle changes in the peptide environment impact thermostability and alloreactivity to be published
7FJD	Cryo-EM structure of a membrane protein(WT) 分子名称: CHOLESTEROL, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ... 著者 Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z. 登録日 2021-08-03 公開日 2022-07-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility. Mol.Cell, 82, 2022
7FJE	Cryo-EM structure of a membrane protein(LL) 分子名称: CHOLESTEROL, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ... 著者 Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z. 登録日 2021-08-03 公開日 2022-07-27 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility. Mol.Cell, 82, 2022
7FJF	Cryo-EM structure of a membrane protein(CS) 分子名称: CHOLEST-5-EN-3-YL HYDROGEN SULFATE, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ... 著者 Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z. 登録日 2021-08-03 公開日 2022-07-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility. Mol.Cell, 82, 2022
6GH1	HLA-E*01:03 in complex with Mtb44 分子名称: Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], MHC class I antigen, ... 著者 Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K. 登録日 2018-05-04 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding. Nat Commun, 9, 2018
6GHN	HLA-E*01:03 in complex with the Mtb44 peptide variant: Mtb44*P9-Phe. 分子名称: ARG-LEU-PRO-ALA-LYS-ALA-PRO-LEU-PHE, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... 著者 Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K. 登録日 2018-05-08 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.542 Å) 主引用文献 Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding. Nat Commun, 9, 2018
8EMA	mouse full length B cell receptor 分子名称: Anti-human Langerin 2G3 lambda chain, B-cell antigen receptor complex-associated protein alpha chain, B-cell antigen receptor complex-associated protein beta chain, ... 著者 Ying, D, Xiong, P, Michael, R. 登録日 2022-09-27 公開日 2022-11-16 最終更新日 2022-12-07 実験手法 ELECTRON MICROSCOPY (8.2 Å) 主引用文献 Structural principles of B cell antigen receptor assembly. Nature, 612, 2022
6ILG	CRYSTAL STRUCTURE OF BAT MHC CLASS I PTAL-N*01:01 FOR 2.6 ANGSTROM 分子名称: Beta-2-microglobulin, HEV-1-P8L, MHC class I antigen 著者 Qu, Z.H, Zhang, N.Z, Xia, C. 登録日 2018-10-18 公開日 2019-07-24 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure and Peptidome of the Bat MHC Class I Molecule Reveal a Novel Mechanism Leading to High-Affinity Peptide Binding. J Immunol., 202, 2019
6K60	Structural and functional basis for HLA-G isoform recognition of immune checkpoint receptor LILRBs 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain G, ... 著者 Kuroki, K, Matsubara, H, Kanda, R, Miyashita, N, Shiroishi, M, Fukunaga, Y, Kamishikiryo, J, Fukunaga, A, Hirose, K, Sugita, Y, Kita, S, Ose, T, Maenaka, K. 登録日 2019-05-31 公開日 2019-11-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.149 Å) 主引用文献 Structural and Functional Basis for LILRB Immune Checkpoint Receptor Recognition of HLA-G Isoforms. J Immunol., 203, 2019

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