5C8L
 
 | | Crystal Structure of the Bdellovibrio bacteriovorus Nucleoside Diphosphate Sugar Hydrolase | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, NudF protein, ... | | 著者 | Gabelli, S.B, de la Pena, A.H, Suarez, A, Amzel, L.M. | | 登録日 | 2015-06-25 | | 公開日 | 2016-01-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus.
Plos One, 10, 2015
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6YWW
 | | MeCP2 is a microsatellite binding protein that protects CA repeats from nucleosome invasion | | 分子名称: | DNA (5'-D(*AP*TP*AP*TP*AP*AP*TP*TP*GP*TP*GP*TP*GP*TP*GP*TP*GP*CP*AP*G)-3'), DNA/RNA (5'-D(*TP*CP*TP*GP*CP*AP*CP*A)-R(P*(5HC))-D(P*AP*CP*AP*CP*AP*AP*TP*TP*AP*TP*A)-3'), Truncated methyl CpG binding protein 2 transcript 1 | | 著者 | Ibrahim, A, Papin, C, Mohideen-Abdul, K, Gras, S.L, Stoll, I, Bronner, C, Dimitrov, S, Klaholz, B.P, Hamiche, A. | | 登録日 | 2020-04-30 | | 公開日 | 2021-06-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | | 主引用文献 | MeCP2 is a microsatellite binding protein that protects CA repeats from nucleosome invasion.
Science, 372, 2021
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7YGF
 | | Crystal structure of YggS from Fusobacterium nucleatum | | 分子名称: | Pyridoxal phosphate homeostasis protein, SULFATE ION | | 著者 | He, S.R, Chan, Y.Y, Wang, L.L, Bai, X, Bu, T.T, Zhang, J, Xu, Y.B. | | 登録日 | 2022-07-11 | | 公開日 | 2022-10-12 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Structural and Functional Analysis of the Pyridoxal Phosphate Homeostasis Protein YggS from Fusobacterium nucleatum.
Molecules, 27, 2022
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7XCT
 | | Cryo-EM structure of Dot1L and H2BK34ub-H3K79Nle nucleosome 2:1 complex | | 分子名称: | DNA (145-MER), Histone H2A, Histone H2B type 1-K, ... | | 著者 | Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L. | | 登録日 | 2022-03-25 | | 公開日 | 2022-04-20 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | | 主引用文献 | H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
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7XD0
 | | cryo-EM structure of H2BK34ub nucleosome | | 分子名称: | DNA (146-MER), Histone H2A, Histone H2B type 1-K, ... | | 著者 | Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L. | | 登録日 | 2022-03-26 | | 公開日 | 2022-04-20 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
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7XCR
 | | Cryo-EM structure of Dot1L and H2BK34ub-H3K79Nle nucleosome 1:1 complex | | 分子名称: | DNA (146-MER), Histone H2A, Histone H2B type 1-K, ... | | 著者 | Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L. | | 登録日 | 2022-03-25 | | 公開日 | 2022-04-20 | | 最終更新日 | 2025-06-25 | | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | | 主引用文献 | H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
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7XD1
 | | cryo-EM structure of unmodified nucleosome | | 分子名称: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | | 著者 | Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L. | | 登録日 | 2022-03-26 | | 公開日 | 2022-04-20 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
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2VRD
 | | THE STRUCTURE OF THE ZINC FINGER FROM THE HUMAN SPLICEOSOMAL PROTEIN U1C | | 分子名称: | U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C, ZINC ION | | 著者 | Muto, Y, Pomeranz-Krummel, D, Oubridge, C, Hernandez, H, Robinson, C, Neuhaus, D, Nagai, K. | | 登録日 | 2008-03-31 | | 公開日 | 2008-04-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Structure and Biochemical Properties of the Human Spliceosomal Protein U1C
J.Mol.Biol., 341, 2004
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3X1V
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3X1U
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5C7Q
 | | Crystal Structure of the Bdellovibrio bacteriovorus Nucleoside Diphosphate Sugar Hydrolase | | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Gabelli, S.B, de la Pena, A.H, Suarez, A, Amzel, L.M. | | 登録日 | 2015-06-24 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus.
Plos One, 10, 2015
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5CCD
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6BUZ
 | | Cryo-EM structure of CENP-A nucleosome in complex with kinetochore protein CENP-N | | 分子名称: | DNA (147-MER), Histone H2A, Histone H2B, ... | | 著者 | Chittori, S, Hong, J, Kelly, A.E, Bai, Y, Subramaniam, S. | | 登録日 | 2017-12-11 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | | 主引用文献 | Structural mechanisms of centromeric nucleosome recognition by the kinetochore protein CENP-N.
Science, 359, 2018
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5C7T
 | | Crystal Structure of the Bdellovibrio bacteriovorus Nucleoside Diphosphate Sugar Hydrolase in complex with ADP-ribose | | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, ADENOSINE-5-DIPHOSPHORIBOSE, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Gabelli, S.B, de la Pena, A.H, Suarez, A, Amzel, L.M. | | 登録日 | 2015-06-24 | | 公開日 | 2016-01-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus.
Plos One, 10, 2015
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3X1T
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4CDO
 | | Crystal structure of PQBP1 bound to spliceosomal U5-15kD | | 分子名称: | THIOREDOXIN-LIKE PROTEIN 4A, POLYGLUTAMINE-BINDING PROTEIN | | 著者 | Mizuguchi, M, Obita, T, Serita, T, Kojima, R, Nabeshima, Y, Okazawa, H. | | 登録日 | 2013-11-05 | | 公開日 | 2014-04-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mutations in the Pqbp1 Gene Prevent its Interaction with the Spliceosomal Protein U5-15Kd.
Nat.Commun., 5, 2014
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1X8C
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6PVU
 | | RNase A in complex with hexametaphosphate | | 分子名称: | 2,4,6,8,10,12-hexahydroxy-2lambda~5~,4lambda~5~,6lambda~5~,8lambda~5~,10lambda~5~,12lambda~5~-cyclohexaphosphoxane-2,4,6,8,10,12-hexone, Ribonuclease pancreatic | | 著者 | Windsor, I.W, Sheppard, S.M, Cummins, C.C, Raines, R.T. | | 登録日 | 2019-07-21 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Nucleoside Tetra- and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent Are Potent Inhibitors of Ribonuclease A.
J.Am.Chem.Soc., 141, 2019
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6PVW
 | | RNase A in complex with cp4pA | | 分子名称: | 2,4,6,8-tetrahydroxy-1,3,5,7,2lambda~5~,4lambda~5~,6lambda~5~,8lambda~5~-tetroxatetraphosphocane-2,4,6,8-tetrone, 5'-O-[(R)-hydroxy{[(4R,8S)-4,6,8-trihydroxy-2,4,6,8-tetraoxo-1,3,5,7,2lambda~5~,4lambda~5~,6lambda~5~,8lambda~5~-tetroxatetraphosphocan-2-yl]oxy}phosphoryl]adenosine, Ribonuclease pancreatic | | 著者 | Windsor, I.W, Sheppard, S.M, Cummins, C.C, Raines, R.T. | | 登録日 | 2019-07-21 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Nucleoside Tetra- and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent Are Potent Inhibitors of Ribonuclease A.
J.Am.Chem.Soc., 141, 2019
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3X1S
 | | Crystal structure of the nucleosome core particle | | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | | 著者 | Sivaraman, P, Kumarevel, T.S. | | 登録日 | 2014-11-27 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.805 Å) | | 主引用文献 | Structural and functional analyses of nucleosome complexes with mouse histone variants TH2a and TH2b, involved in reprogramming
Biochem.Biophys.Res.Commun., 464, 2015
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6PVX
 | | RNase A in complex with p5U | | 分子名称: | 5'-O-[(R)-hydroxy{[(S)-hydroxy{[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]oxy}phosphoryl]uridine, Ribonuclease pancreatic | | 著者 | Windsor, I.W, Sheppard, S.M, Cummins, C.C, Raines, R.T. | | 登録日 | 2019-07-21 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Nucleoside Tetra- and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent Are Potent Inhibitors of Ribonuclease A.
J.Am.Chem.Soc., 141, 2019
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7LYC
 | | Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A Lys13 and Lys15 in complex with BARD1 (residues 415-777) | | 分子名称: | BRCA1-associated RING domain protein 1, DNA (146-MER), DNA (147-MER), ... | | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, D, Mer, E, Mer, G. | | 登録日 | 2021-03-06 | | 公開日 | 2021-06-16 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | | 主引用文献 | Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation.
Nature, 596, 2021
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6PVV
 | | RNase A in complex with p5A | | 分子名称: | ADENOSINE-5'-PENTAPHOSPHATE, Ribonuclease pancreatic | | 著者 | Windsor, I.W, Sheppard, S.M, Cummins, C.C, Raines, R.T. | | 登録日 | 2019-07-21 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Nucleoside Tetra- and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent Are Potent Inhibitors of Ribonuclease A.
J.Am.Chem.Soc., 141, 2019
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5BSK
 | | Human HGPRT in complex with (S)-HPEPG, an acyclic nucleoside phosphonate | | 分子名称: | (2-{[(2S)-1-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxypropan-2-yl]oxy}ethyl)phosphonic acid, Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION | | 著者 | Keough, D.T, Guddat, L.W, Kaiser, M.M, Hockova, D, Wang, T.-H, Janeba, Z. | | 登録日 | 2015-06-02 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Synthesis and Evaluation of Novel Acyclic Nucleoside Phosphonates as Inhibitors of Plasmodium falciparum and Human 6-Oxopurine Phosphoribosyltransferases.
Chemmedchem, 10, 2015
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6KSW
 | | Cryo-EM structure of the human concentrative nucleoside transporter CNT3 | | 分子名称: | Solute carrier family 28 member 3 | | 著者 | Zhou, Y.X, Liao, L.H, Li, J.L, Xiao, Q.J, Sun, L.F, Deng, D. | | 登録日 | 2019-08-26 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structure of the human concentrative nucleoside transporter CNT3.
Plos Biol., 18, 2020
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