8QBK
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8QBL
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6R64
| N-terminal domain of modification dependent EcoKMcrA restriction endonuclease (NEco) in complex with C5mCGG target sequence | 分子名称: | 5-methylcytosine-specific restriction enzyme A, DNA (5'-D(*GP*AP*AP*CP*(5CM)P*GP*GP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*CP*(5CM)P*GP*GP*TP*TP*C)-3') | 著者 | Slyvka, A, Zagorskaite, E, Czapinska, H, Sasnauskas, G, Bochtler, M. | 登録日 | 2019-03-26 | 公開日 | 2019-10-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping. Nucleic Acids Res., 47, 2019
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5JDK
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7SVU
| TnsBctd-TnsC-TniQ complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (28-MER), DNA (29-MER), ... | 著者 | Park, J, Tsai, A.W.T, Kellogg, E.H. | 登録日 | 2021-11-19 | 公開日 | 2022-11-23 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structures of the holo CRISPR RNA-guided transposon integration complex Nature, 613, 2023
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8I53
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2HYE
| Crystal Structure of the DDB1-Cul4A-Rbx1-SV5V Complex | 分子名称: | Cullin-4A, DNA damage-binding protein 1, Nonstructural protein V, ... | 著者 | Angers, S, Li, T, Yi, X, MacCoss, M.J, Moon, R.T, Zheng, N. | 登録日 | 2006-08-05 | 公開日 | 2006-10-03 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. Nature, 443, 2006
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3AV1
| The human nucleosome structure containing the histone variant H3.2 | 分子名称: | 146-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Tachiwana, H, Osakabe, A, Shiga, T, Miya, Y, Kimura, H, Kagawa, W, Kurumizaka, H. | 登録日 | 2011-02-18 | 公開日 | 2011-06-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structures of human nucleosomes containing major histone H3 variants Acta Crystallogr.,Sect.D, 67, 2011
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2GPX
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1K3W
| Crystal structure of a trapped reaction intermediate of the DNA Repair Enzyme Endonuclease VIII with DNA | 分子名称: | 5'-D(*CP*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3', 5'-D(*GP*GP*CP*TP*TP*CP*AP*TP*CP*CP*TP*GP*G)-3', Endonuclease VIII, ... | 著者 | Golan, G, Zharkov, D.O, Gilboa, R, Fernandes, A.S, Kycia, J.H, Gerchman, S.E, Rieger, R.A, Grollman, A.P, Shoham, G. | 登録日 | 2001-10-04 | 公開日 | 2002-10-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Structural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediate. EMBO J., 21, 2002
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4QLC
| Crystal structure of chromatosome at 3.5 angstrom resolution | 分子名称: | CITRIC ACID, DNA (167-mer), H5, ... | 著者 | Jiang, J.S, Zhou, B.R, Xiao, T.S, Bai, Y.W. | 登録日 | 2014-06-11 | 公開日 | 2015-07-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.503 Å) | 主引用文献 | Structural Mechanisms of Nucleosome Recognition by Linker Histones. Mol.Cell, 33 Suppl 1, 2015
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4HT4
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5XF8
| Cryo-EM structure of the Cdt1-MCM2-7 complex in AMPPNP state | 分子名称: | Cell division cycle protein CDT1, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, ... | 著者 | Zhai, Y, Cheng, E, Wu, H, Li, N, Yung, P.Y, Gao, N, Tye, B.K. | 登録日 | 2017-04-09 | 公開日 | 2017-05-03 | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | 主引用文献 | Open-ringed structure of the Cdt1-Mcm2-7 complex as a precursor of the MCM double hexamer Nat. Struct. Mol. Biol., 24, 2017
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8IYQ
| Structure of CbCas9 bound to 20-nucleotide complementary DNA substrate | 分子名称: | NTS, TS, deadCbCas9, ... | 著者 | Zhang, S, Lin, S, Liu, J.J.G. | 登録日 | 2023-04-05 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.46 Å) | 主引用文献 | Pro-CRISPR PcrIIC1-associated Cas9 system for enhanced bacterial immunity. Nature, 630, 2024
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4IQV
| Tdt core in complex with inhibitor 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid and ssDNA | 分子名称: | 5'-D(*GP*CP*CP*G)-3', 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, DNA nucleotidylexotransferase, ... | 著者 | Gouge, J, Delarue, M. | 登録日 | 2013-01-13 | 公開日 | 2013-09-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target. J.Med.Chem., 56, 2013
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4IQW
| Tdt core in complex with inhibitor (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid and ssDNA | 分子名称: | (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, 5'-D(*GP*CP*CP*G)-3', DNA nucleotidylexotransferase, ... | 著者 | Gouge, J, Delarue, M. | 登録日 | 2013-01-13 | 公開日 | 2013-09-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target. J.Med.Chem., 56, 2013
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7YWX
| Structure of the human CCAN CENP-A alpha-satellite complex | 分子名称: | Centromere protein C, Centromere protein H, Centromere protein I, ... | 著者 | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | 登録日 | 2022-02-14 | 公開日 | 2022-05-18 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (12 Å) | 主引用文献 | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
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8WMH
| Structure of CbCas9 bound to 6-nucleotide complementary DNA substrate | 分子名称: | NTS, TS, deadCbCas9, ... | 著者 | Zhang, S, Lin, S, Liu, J.J.G. | 登録日 | 2023-10-03 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Pro-CRISPR PcrIIC1-associated Cas9 system for enhanced bacterial immunity. Nature, 630, 2024
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8WMM
| Structure of CbCas9-PcrIIC1 complex bound to 28-bp DNA substrate (20-nt complementary) | 分子名称: | MAGNESIUM ION, NTS, PcrIIC1, ... | 著者 | Zhang, S, Lin, S, Liu, J.J.G. | 登録日 | 2023-10-04 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Pro-CRISPR PcrIIC1-associated Cas9 system for enhanced bacterial immunity. Nature, 630, 2024
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6T21
| N-terminal domain of EcoKMcrA restriction endonuclease (NEco) in complex with T5mCGA target sequence | 分子名称: | 5-methylcytosine-specific restriction enzyme A, DNA (5'-D(*GP*AP*AP*TP*(5CM)P*GP*AP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*TP*(5CM)P*GP*AP*TP*TP*C)-3') | 著者 | Slyvka, A, Zagorskaite, E, Czapinska, H, Sasnauskas, G, Bochtler, M. | 登録日 | 2019-10-07 | 公開日 | 2019-10-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping. Nucleic Acids Res., 47, 2019
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3W98
| Crystal Structure of Human Nucleosome Core Particle lacking H3.1 N-terminal region | 分子名称: | 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H. | 登録日 | 2013-04-01 | 公開日 | 2013-08-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | 主引用文献 | Contribution of histone N-terminal tails to the structure and stability of nucleosomes FEBS Open Bio, 3, 2013
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4BE1
| PFV intasome with inhibitor XZ-116 | 分子名称: | 17 NUCLEOTIDE PREPROCESSED PFV DONOR DNA (TRANSFERRED STRAND), 19 NUCLEOTIDE PREPROCESSED PFV DONOR DNA (NON-TRANSFERRED STRAND), 2-(3-chloro-2-fluorobenzyl)-6,7-dihydroxy-2,3-dihydro-1H-isoindol-1-one, ... | 著者 | Hare, S, Cherepanov, P. | 登録日 | 2012-10-08 | 公開日 | 2012-10-31 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Activities, Crystal Structures and Molecular Dynamics of Dihydro-1H-Isoindole Derivatives, Inhibitors of HIV-1 Integrase. Acs Chem.Biol., 8, 2013
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3W97
| Crystal Structure of Human Nucleosome Core Particle lacking H2B N-terminal region | 分子名称: | 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H. | 登録日 | 2013-04-01 | 公開日 | 2013-08-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Contribution of histone N-terminal tails to the structure and stability of nucleosomes FEBS Open Bio, 3, 2013
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8FNJ
| Structure of E138K/G140A HIV-1 intasome with Dolutegravir bound | 分子名称: | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... | 著者 | Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. | 登録日 | 2022-12-27 | 公開日 | 2023-08-09 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
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8FNN
| Structure of E138K/G140A/Q148K HIV-1 intasome with Dolutegravir bound | 分子名称: | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... | 著者 | Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. | 登録日 | 2022-12-27 | 公開日 | 2023-08-09 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
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