PDB: 215264 件ウェブページステータス検索Chemie searchBIRD

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6MZJ	Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 2 Fabs bound, sharpened map 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ... 著者 Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D. 登録日 2018-11-05 公開日 2018-11-14 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core. Elife, 7, 2018
8P2L	A CHIMERA construct containing human SARM1 ARM and SAM domains and C. elegans TIR domain. 分子名称: NAD(+) hydrolase SARM1,NAD(+) hydrolase tir-1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Isupov, M.N, Opatowsky, Y. 登録日 2023-05-16 公開日 2023-09-06 実験手法 ELECTRON MICROSCOPY (2.68 Å) 主引用文献 Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans. Cell Rep, 42, 2023
8P9Y	SARS-CoV-2 S protein S:D614G mutant in 3-down with binding site of an entry inhibitor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ... 著者 Adhav, A, Forcada-Nadal, A, Marco-Marin, C, Lopez-Redondo, M.L, Llacer, J.L. 登録日 2023-06-06 公開日 2023-09-27 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein. J.Med.Chem., 66, 2023
8P99	SARS-CoV-2 S-protein:D614G mutant in 1-up conformation 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1,Spike glycoprotein 著者 Adhav, A, Forcada-Nadal, A, Marco-Marin, C, Lopez-Redondo, M.L, Llacer, J.L. 登録日 2023-06-05 公開日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein. J.Med.Chem., 66, 2023
5KJQ	X-ray structure of PcCel45A in complex with cellobiose expressed in Aspergillus nidullans 分子名称: Endoglucanase V-like protein, SULFATE ION, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose 著者 Godoy, A.S, Ramia, M.P, Camilo, C.M, Polikarpov, I. 登録日 2016-06-20 公開日 2017-06-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.704 Å) 主引用文献 Structure, computational and biochemical analysis of PcCel45A endoglucanase from Phanerochaete chrysosporium and catalytic mechanisms of GH45 subfamily C members. Sci Rep, 8, 2018
8BA1	CTD12-CTD12 heterodimer from CPSF73 and CPSF100 分子名称: Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor subunit 3 著者 Thore, S, Mackereth, C. 登録日 2022-10-10 公開日 2023-05-03 最終更新日 2023-12-06 実験手法 SOLUTION NMR 主引用文献 Molecular details of the CPSF73-CPSF100 C-terminal heterodimer and interaction with Symplekin. Open Biology, 13, 2023
8TTP	Crystal structure of class C beta-lactamase from Escherichia coli in complex with avibactam 分子名称: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1,2-ETHANEDIOL, Beta-lactamase, ... 著者 Chang, C, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Biology of Infectious Diseases (CSBID) 登録日 2023-08-14 公開日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Crystal structure of class C beta-lactamase from Escherichia coli in complex with avibactam to be published
4TNC	REFINED STRUCTURE OF CHICKEN SKELETAL MUSCLE TROPONIN C IN THE TWO-CALCIUM STATE AT 2-ANGSTROMS RESOLUTION 分子名称: CALCIUM ION, TROPONIN C 著者 Sundaralingam, M. 登録日 1987-09-28 公開日 1988-07-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Refined structure of chicken skeletal muscle troponin C in the two-calcium state at 2-A resolution. J.Biol.Chem., 263, 1988
5JVE	L16I mutant of cytochrome c prime from Alcaligenes xylosoxidans: Ferrous state 分子名称: Cytochrome c', HEME C 著者 Kekilli, D, Strange, R.W, Hough, M.A. 登録日 2016-05-11 公開日 2017-03-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Engineering proximal vs. distal heme-NO coordination via dinitrosyl dynamics: implications for NO sensor design. Chem Sci, 8, 2017
7UJ2	OspC Type B 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Outer surface protein C 著者 Rudolph, M.J, Mantis, N. 登録日 2022-03-30 公開日 2023-04-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.503 Å) 主引用文献 Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi. Mbio, 14, 2023
6XG1	Class C beta-lactamase from Escherichia coli 分子名称: 1,2-ETHANEDIOL, Beta-lactamase 著者 Chang, C, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2020-06-16 公開日 2020-06-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 Class C beta-lactamase from Escherichia coli To Be Published
6GC5	Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM 分子名称: AU-rich RNA, ELAV-like protein 1 著者 Ripin, N, Allain, F.H. 登録日 2018-04-17 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6EI2	Crystal Structure of HLA-A68 presenting a C-terminally extended peptide 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, CADMIUM ION, ... 著者 Picaud, S, Guillaume, P, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gfeller, D, Filippakopoulos, P. 登録日 2017-09-16 公開日 2017-10-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Crystal Structure of HLA-A68 presenting a C-terminally extended peptide To Be Published
7CJX	UDP-glucuronosyltransferase 2B15 C-terminal domain-L446S 分子名称: L(+)-TARTARIC ACID, UDP-glucuronosyltransferase 2B15 著者 Wang, C.Y, Zhang, L. 登録日 2020-07-14 公開日 2021-07-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.986414 Å) 主引用文献 Structure of UDP-glucuronosyltransferase 2B15 C-terminal domain L446S at 1.99 Angstroms resolution To Be Published
7MRI	Crystal structure of N63T yeast iso-1-cytochrome c 分子名称: Cytochrome c isoform 1, HEME C 著者 Lei, H, Bowler, B.E, Evenson, G.E. 登録日 2021-05-07 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Effect on intrinsic peroxidase activity of substituting coevolved residues from Omega-loop C of human cytochrome c into yeast iso-1-cytochrome c. J.Inorg.Biochem., 232, 2022
5ETX	Crystal structure of HCV NS3/4A protease A156T variant in complex with 5172-Linear (MK-5172 linear analogue) 分子名称: CHLORIDE ION, NS3 protease, ZINC ION, ... 著者 Soumana, D, Yilmaz, N.K, Ali, A, Prachanronarong, K.L, Aydin, C, Schiffer, C.A. 登録日 2015-11-18 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural and Thermodynamic Effects of Macrocyclization in HCV NS3/4A Inhibitor MK-5172. Acs Chem.Biol., 11, 2016
7B3T	Crystal structure of c-MET bound by compound 2 分子名称: 3-(phenylmethyl)-1~{H}-pyrrolo[2,3-b]pyridine, CHLORIDE ION, Hepatocyte growth factor receptor, ... 著者 Collie, G.W. 登録日 2020-12-01 公開日 2020-12-09 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Structural Basis for Targeting the Folded P-Loop Conformation of c-MET. Acs Med.Chem.Lett., 12, 2021
7B41	Crystal structure of c-MET bound by compound 7 分子名称: 3-[(2-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{H}-pyrrolo[2,3-b]pyridine, Hepatocyte growth factor receptor 著者 Collie, G.W. 登録日 2020-12-02 公開日 2020-12-09 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structural Basis for Targeting the Folded P-Loop Conformation of c-MET. Acs Med.Chem.Lett., 12, 2021
5J5E	crystal structure of antigen-ERAP1 domain complex 分子名称: Endoplasmic reticulum aminopeptidase 1 著者 Sui, L, Gandhi, A, Guo, H.-C. 登録日 2016-04-02 公開日 2017-04-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of a polypeptide's C-terminus in complex with the regulatory domain of ER aminopeptidase 1. Mol.Immunol., 80, 2016
5G04	Structure of the human APC-Cdc20-Hsl1 complex 分子名称: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ... 著者 Zhang, S, Chang, L, Alfieri, C, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D. 登録日 2016-03-16 公開日 2016-05-25 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Molecular Mechanism of Apc/C Activation by Mitotic Phosphorylation. Nature, 533, 2016
4QL1	Crystal structure of human WDR5 in complex with compound OICR-9429 分子名称: 1,2-ETHANEDIOL, GLYCEROL, N-(4-(4-methylpiperazin-1-yl)-3'-(morpholinomethyl)-[1,1'-biphenyl]-3-yl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide, ... 著者 Dong, A, Dombrovski, L, Walker, J.R, Getlik, M, Kuznetsova, E, Smil, D, Barsyte, D, Li, F, Poda, G, Senisterra, G, Marcellus, R, Al-Awar, R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Schapira, M, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC) 登録日 2014-06-10 公開日 2014-12-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Pharmacological targeting of the Wdr5-MLL interaction in C/EBP alpha N-terminal leukemia. Nat.Chem.Biol., 11, 2015
6P2D	Structure of mouse ketohexokinase-C in complex with fructose and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Ketohexokinase, NITRATE ION, ... 著者 Gasper, W.C, Allen, K.N, Tolan, D.R. 登録日 2019-05-21 公開日 2020-06-03 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Michaelis-like complex of mouse ketohexokinase isoform C ACTA CRYSTALLOGR.,SECT.D, 2024
2V23	Structure of cytochrome c peroxidase mutant N184R Y36A 分子名称: CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE 著者 Metcalfe, C.L, Macdonald, I.K, Brown, K.A, Raven, E.L, Moody, P.C.E. 登録日 2007-05-31 公開日 2007-12-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Tuberculosis Prodrug Isoniazid Bound to Activating Peroxidases. J.Biol.Chem., 283, 2008
8R4Z	Crystal structure of alpha keto acid C-methyl-transferases MrsA native-form 分子名称: 2-ketoarginine methyltransferase, MAGNESIUM ION 著者 Gerhardt, S, Kemper, F, Andexer, J.N. 登録日 2023-11-15 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Structures and protein engineering of the alpha-keto acid C-methyltransferases SgvM and MrsA for rational substrate transfer. Chembiochem, 2024
8JN8	Crystal structure of c-Src in complex with covalent inhibitor DC-Srci-6668 分子名称: (2R)-N-cyclopentyl-2-[cyclopropyl(ethanoyl)amino]-2-(4-fluorophenyl)ethanamide, Proto-oncogene tyrosine-protein kinase Src 著者 Zhang, H.M, Luo, C. 登録日 2023-06-06 公開日 2024-06-12 実験手法 X-RAY DIFFRACTION (1.902 Å) 主引用文献 The crystal structure of c-Src in complex with covalent inhibitor DC-Srci-6668 To Be Published

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