7PD2

Crystal structure of the substrate-free radical SAM tyrosine lyase ThiH (2-iminoacetate synthase) from Thermosinus carboxydivorans

Summary for 7PD2

Entry DOI	10.2210/pdb7pd2/pdb
Related	7PD1
Descriptor	Thiazole biosynthesis protein ThiH, IRON/SULFUR CLUSTER, 5'-DEOXYADENOSINE, ... (7 entities in total)
Functional Keywords	radical sam enzyme 2-iminoacetate metalloprotein, lyase
Biological source	Thermosinus carboxydivorans Nor1
Total number of polymer chains	2
Total formula weight	88426.99
Authors	Amara, P.,Saragaglia, C.,Mouesca, J.-M.,Martin, L.,Nicolet, Y. (deposition date: 2021-08-04, release date: 2022-05-11, Last modification date: 2024-01-31)
Primary citation	Amara, P.,Saragaglia, C.,Mouesca, J.M.,Martin, L.,Nicolet, Y. L-tyrosine-bound ThiH structure reveals C-C bond break differences within radical SAM aromatic amino acid lyases. Nat Commun, 13:2284-2284, 2022 Cited by PubMed: 35477710 DOI: 10.1038/s41467-022-29980-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.99 Å)

Structure validation