PDB: 2579 件ウェブページステータス検索Chemie searchBIRD

---

3JU6	Crystal Structure of Dimeric Arginine Kinase in Complex with AMPPNP and Arginine 分子名称: ARGININE, Arginine kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Wu, X, Ye, S, Guo, S, Yan, W, Bartlam, M, Rao, Z. 登録日 2009-09-14 公開日 2009-09-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural basis for a reciprocating mechanism of negative cooperativity in dimeric phosphagen kinase activity Faseb J., 24, 2010
3JU5	Crystal Structure of Dimeric Arginine Kinase at 1.75-A Resolution 分子名称: Arginine kinase, MAGNESIUM ION 著者 Wu, X, Ye, S, Guo, S, Yan, W, Bartlam, M, Rao, Z. 登録日 2009-09-14 公開日 2009-09-29 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural basis for a reciprocating mechanism of negative cooperativity in dimeric phosphagen kinase activity Faseb J., 24, 2010
5FBS	Crystal structure of rifampin phosphotransferase RPH-Lm from Listeria monocytogenes in complex with ADP and magnesium 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphoenolpyruvate synthase 著者 Stogios, P.J, Wawrzak, Z, Skarina, T, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2015-12-14 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Rifampin phosphotransferase is an unusual antibiotic resistance kinase. Nat Commun, 7, 2016
7LGJ	Cyanophycin synthetase 1 from Synechocystis sp. UTEX2470 with ADPCP and 8x(Asp-Arg)-NH2 分子名称: 8x(Asp-Arg)-NH2, Cyanophycin synthase, MAGNESIUM ION, ... 著者 Sharon, I, Grogg, M, Hilvert, D, Schmeing, T.M. 登録日 2021-01-20 公開日 2021-08-18 最終更新日 2021-10-06 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structures and function of the amino acid polymerase cyanophycin synthetase. Nat.Chem.Biol., 17, 2021
6KC0	fused To-MtbCsm1 with 2ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A),CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), MAGNESIUM ION 著者 Li, T, Huo, Y, Jiang, T. 登録日 2019-06-26 公開日 2020-07-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.295 Å) 主引用文献 Mycobacterium tuberculosis CRISPR/Cas system Csm1 holds clues to the evolutionary relationship between DNA polymerase and cyclase activity. Int.J.Biol.Macromol., 170, 2020
1EZZ	CRYSTAL STRUCTURE OF E. COLI ASPARTATE TRANSCARBAMOYLASE P268A MUTANT IN THE T-STATE 分子名称: ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ZINC ION 著者 Jin, L, Stec, B, Kantrowitz, E.R. 登録日 2000-05-12 公開日 2000-11-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A cis-proline to alanine mutant of E. coli aspartate transcarbamoylase: kinetic studies and three-dimensional crystal structures. Biochemistry, 39, 2000
6FLF	Deoxyguanylosuccinate synthase (DgsS) structure at 1.33 Angstrom resolution. 分子名称: Adenylosuccinate synthetase 著者 Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. 登録日 2018-01-25 公開日 2019-06-12 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes. Science, 372, 2021
4E7W	Structure of GSK3 from Ustilago maydis 分子名称: Glycogen Synthase Kinase 3 著者 Gruetter, C, Rauh, D. 登録日 2012-03-19 公開日 2012-05-16 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Targeting GSK3 from Ustilago maydis: Type-II Kinase Inhibitors as Potential Antifungals. Acs Chem.Biol., 7, 2012
7O71	Cryo-EM structure of a respiratory complex I 分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), ... 著者 Parey, K, Vonck, J. 登録日 2021-04-12 公開日 2021-11-10 最終更新日 2021-12-01 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism. Sci Adv, 7, 2021
7O6Y	Cryo-EM structure of respiratory complex I under turnover 分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... 著者 Parey, K, Vonck, J. 登録日 2021-04-12 公開日 2021-11-10 最終更新日 2021-12-01 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism. Sci Adv, 7, 2021
7F5X	GK domain of Drosophila P5CS filament with glutamate 分子名称: Delta-1-pyrroline-5-carboxylate synthase, GAMMA-L-GLUTAMIC ACID 著者 Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. 登録日 2021-06-23 公開日 2022-04-06 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis of dynamic P5CS filaments. Elife, 11, 2022
7F5T	Drosophila P5CS filament with glutamate 分子名称: Delta-1-pyrroline-5-carboxylate synthase, GLUTAMIC ACID 著者 Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. 登録日 2021-06-22 公開日 2022-05-18 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural basis of dynamic P5CS filaments. Elife, 11, 2022
8J0F	GK tetramer with adjacent hooks at reaction state 分子名称: ADENOSINE-5'-DIPHOSPHATE, Delta-1-pyrroline-5-carboxylate synthase B, GAMMA-GLUTAMYL PHOSPHATE, ... 著者 Zhang, T, Guo, C.J, Liu, J.L. 登録日 2023-04-10 公開日 2024-04-17 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Dynamic Arabidopsis P5CS filament facilitates substrate channelling. Nat.Plants, 10, 2024
4R7G	Determination of the formylglycinamide ribonucleotide amidotransferase ammonia pathway by combining 3D-RISM theory with experiment 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphoribosylformylglycinamidine synthase, ... 著者 Tanwar, A.S, Sindhikara, D.J, Hirata, F, Anand, R. 登録日 2014-08-27 公開日 2015-01-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Determination of the formylglycinamide ribonucleotide amidotransferase ammonia pathway by combining 3D-RISM theory with experiment. Acs Chem.Biol., 10, 2015
6IY6	Crystal structure of human cytosolic aspartyl-tRNA synthetase (DRS) in complex with glutathion-S transferase (GST) domains from Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) and glutamyl-prolyl-tRNA synthetase (EPRS) 分子名称: Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, Aspartate--tRNA ligase, cytoplasmic, ... 著者 Park, S.H, Hahn, H, Han, B.W. 登録日 2018-12-13 公開日 2019-09-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 The DRS-AIMP2-EPRS subcomplex acts as a pivot in the multi-tRNA synthetase complex. Iucrj, 6, 2019
6TNH	Deoxyguanylosuccinate synthase (DgsS) quaternary structure with AMPPcP, dGMP, Asp, Magnesium at 2.21 Angstrom resolution 分子名称: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ASPARTIC ACID, Adenylosuccinate synthetase, ... 著者 Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. 登録日 2019-12-08 公開日 2020-12-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes. Science, 372, 2021
7OLH	Bacillus subtilis Complex structure 1 of diadenylate cyclase CdaA cytoplasmic domain (CdaACD) and the phosphoglucomutase GlmM short variant (GlmMF369) 分子名称: Cyclic di-AMP synthase CdaA, Phosphoglucosamine mutase 著者 Pathania, M, Grundling, A.G, Freemont, P. 登録日 2021-05-20 公開日 2021-10-27 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM. J.Biol.Chem., 297, 2021
7OJS	Complex structure 2 of the Bacillus subtilis CdaA c-di-AMP cyclase domain (CdaACD) and the phosphoglucomutase GlmM short variant (GlmMF369) 分子名称: Cyclic di-AMP synthase CdaA, Phosphoglucosamine mutase 著者 Pathania, M, Grundling, A.G, Freemont, P. 登録日 2021-05-17 公開日 2021-10-27 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM. J.Biol.Chem., 297, 2021
3S5J	2.0A Crystal structure of human phosphoribosyl pyrophosphate synthetase 1 分子名称: Ribose-phosphate pyrophosphokinase 1, SULFATE ION 著者 Chen, P, Teng, M, Li, X. 登録日 2011-05-23 公開日 2012-05-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations Plos One, 10, 2015
8G23	Structure of Ternary Complex of cGAS with dsDNA and Bound pppIpA 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-02-03 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
4PZV	Crystal structure of Francisella tularensis HPPK-DHPS in complex with bisubstrate analog HPPK inhibitor J1D 分子名称: 1,2-ETHANEDIOL, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase/dihydropteroate synthase, 5'-{[2-({N-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)carbonyl]glycyl}amino)ethyl]sulfonyl}-5'-deoxyadenosine 著者 Shaw, G.X, Shi, G, Ji, X. 登録日 2014-03-31 公開日 2014-07-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.704 Å) 主引用文献 Structural enzymology and inhibition of the bi-functional folate pathway enzyme HPPK-DHPS from the biowarfare agent Francisella tularensis. Febs J., 281, 2014
7LVP	Cryptococcus neoformans AIR synthetase 分子名称: 1,2-ETHANEDIOL, AIR synthase, GLYCINE, ... 著者 Chua, S.M.H, Luo, Z, Lim, B.Y.J, Kobe, B, Fraser, J.A. 登録日 2021-02-26 公開日 2021-08-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets. J.Biol.Chem., 297, 2021
4NYE	Structures of SAICAR Synthetase (PurC) from Streptococcus pneumoniae with ADP, Mg2+, AIR and L-Asp 分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Fung, L.W.-M, Johnson, M.E, Abad-Zapatero, C, Wolf, N.M. 登録日 2013-12-10 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Structures of SAICAR synthetase (PurC) from Streptococcus pneumoniae with ADP, Mg(2+), AIR and Asp. Acta Crystallogr.,Sect.D, 70, 2014
4XB6	Structure of the E. coli C-P lyase core complex 分子名称: Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, ... 著者 Brodersen, D.E. 登録日 2014-12-16 公開日 2015-08-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural insights into the bacterial carbon-phosphorus lyase machinery. Nature, 525, 2015
5V8O	Discovery of a high affinity inhibitor of cGAS 分子名称: 5-phenyltetrazolo[1,5-a]pyrimidin-7-ol, Cyclic GMP-AMP synthase, ZINC ION 著者 Hall, J. 登録日 2017-03-22 公開日 2017-09-27 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay. PLoS ONE, 12, 2017

<51525354555657585960616263646566>