PDB: 226262 件ウェブページステータス検索Chemie searchBIRD

---

4KQ5	Crystal Structure of Human Farnesyl Pyrophosphate Synthase Mutant (Y204A) Complexed with Mg and Zoledronate 分子名称: 1,2-ETHANEDIOL, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... 著者 Barnett, B.L, Tsoumpra, M.K, Muniz, J.R.C. 登録日 2013-05-14 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of Human Farnesyl Pyrophosphate Synthase Mutant (Y204A) Complexed with Mg and Zoledronate To be Published
3DC2	Crystal structure of serine bound D-3-phosphoglycerate dehydrogenase from Mycobacterium tuberculosis 分子名称: D-3-phosphoglycerate dehydrogenase, L(+)-TARTARIC ACID, SERINE 著者 Dey, S, Sacchettini, J.C. 登録日 2008-06-03 公開日 2008-07-22 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural analysis of substrate and effector binding in Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase Biochemistry, 47, 2008
4KQD	The crystal Structure of the N-terminal PAS domain of the F plasmid TraJ 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, DITHIANE DIOL, GLYCEROL, ... 著者 Lu, J, Glover, J.N.M. 登録日 2013-05-14 公開日 2014-07-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 The crystal Structure of the N-terminal PAS domain of the F plasmid TraJ To be Published
3DCN	Glomerella cingulata apo cutinase 分子名称: Cutinase 著者 Nyon, M.P, Rice, D.W, Berrisford, J.M, Hounslow, A.M, Moir, A.J.G, Huang, H, Nathan, S, Mahadi, N.M, Farah Diba, A.B, Craven, C.J. 登録日 2008-06-04 公開日 2008-11-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Catalysis by Glomerella cingulata Cutinase Requires Conformational Cycling between the Active and Inactive States of Its Catalytic Triad J.Mol.Biol., 385, 2009
3ML9	Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04691502 through Structure Based Drug Design 分子名称: 2-amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8H)-one, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 著者 Knighton, D.R. 登録日 2010-04-16 公開日 2010-06-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design. ACS Med Chem Lett, 4, 2013
3MLO	DNA binding domain of Early B-cell Factor 1 (Ebf1) bound to DNA (Crystal form I) 分子名称: DNA (5'-D(*CP*TP*TP*TP*AP*TP*TP*CP*CP*CP*AP*TP*GP*GP*GP*AP*AP*TP*AP*AP*AP*G)-3'), Transcription factor COE1, ZINC ION 著者 Treiber, N, Treiber, T, Zocher, G, Grosschedl, R. 登録日 2010-04-17 公開日 2010-12-01 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins Genes Dev., 24, 2010
3DA9	Crystal structure of thrombin in complex with inhibitor 分子名称: Hirudin peptide, SODIUM ION, Thrombin heavy chain, ... 著者 Xue, Y, Hansson, S.K. 登録日 2008-05-29 公開日 2009-05-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Compounds binding to the S2-S3 pockets of thrombin. J.Med.Chem., 52, 2009
4KLA	E343D variant of human ferrochelatase 分子名称: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... 著者 Lanzilotta, W.N, Medlock, A.E. 登録日 2013-05-07 公開日 2014-05-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 E343D variant of human ferrochelatase To be Published
3M3Z	Crystal structure of HSC70/BAG1 in complex with small molecule inhibitor 分子名称: 5'-O-(2-amino-2-oxoethyl)-8-(methylamino)adenosine, BAG family molecular chaperone regulator 1, Heat shock cognate 71 kDa protein 著者 Dokurno, P, Surgenor, A.E, Shaw, T, Macias, A.T, Massey, A.J, Williamson, D.S. 登録日 2010-03-10 公開日 2011-01-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity. J.Med.Chem., 54, 2011
4WE5	The crystal structure of hemagglutinin from A/Port Chalmers/1/1973 influenza virus 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... 著者 Yang, H, Carney, P.J, Chang, J.C, Guo, Z, Villanueva, J.M, Stevens, J. 登録日 2014-09-09 公開日 2015-02-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and receptor binding preferences of recombinant human A(H3N2) virus hemagglutinins. Virology, 477C, 2015
3DBG	Crystal structure of Cytochrome P450 170A1 (CYP170A1) from Streptomyces coelicolor 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 著者 Zhao, B, Vassylyev, D.G, Waterman, M.R. 登録日 2008-05-31 公開日 2009-06-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site J.Biol.Chem., 284, 2009
3M4A	Crystal structure of a bacterial topoisomerase IB in complex with DNA reveals a secondary DNA binding site 分子名称: ACETIC ACID, DNA (5'-D(*GP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*CP*CP*CP*TP*TP*AP*TP*TP*C)-3'), ... 著者 Patel, A, Yakovleva, L, Shuman, S, Mondragon, A. 登録日 2010-03-10 公開日 2010-07-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of a bacterial topoisomerase IB in complex with DNA reveals a secondary DNA binding site. Structure, 18, 2010
4KQO	Crystal structure of penicillin-binding protein 3 from pseudomonas aeruginosa in complex with piperacillin 分子名称: CHLORIDE ION, GLYCEROL, IMIDAZOLE, ... 著者 Nettleship, J.E, Stuart, D.I, Owens, R.J, Ren, J. 登録日 2013-05-15 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Binding of (5S)-Penicilloic Acid to Penicillin Binding Protein 3. Acs Chem.Biol., 8, 2013
3M4O	RNA polymerase II elongation complex B 分子名称: DNA (28-MER), DNA (5'-D(P*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Wang, D, Zhu, G, Huang, X, Lippard, S.J. 登録日 2010-03-11 公開日 2010-05-12 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3.57 Å) 主引用文献 X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct. Proc.Natl.Acad.Sci.USA, 107, 2010
3MM9	Dissimilatory sulfite reductase nitrite complex 分子名称: IRON/SULFUR CLUSTER, NITRITE ION, SIROHEME, ... 著者 Parey, K, Warkentin, E, Kroneck, P.M.H, Ermler, U. 登録日 2010-04-19 公開日 2010-07-21 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Reaction cycle of the dissimilatory sulfite reductase from Archaeoglobus fulgidus. Biochemistry, 49, 2010
3DD6	Crystal structure of Rph, an exoribonuclease from Bacillus anthracis at 1.7 A resolution 分子名称: Ribonuclease PH, SULFATE ION 著者 Rawlings, A.E, Blagova, E.V, Levdikov, V.M, Fogg, M.J, Wilson, K.S, Wilkinson, A.J, Structural Proteomics in Europe 2 (SPINE-2) 登録日 2008-06-05 公開日 2009-02-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.702 Å) 主引用文献 The structure of Rph, an exoribonuclease from Bacillus anthracis, at 1.7 A resolution. Acta Crystallogr.,Sect.F, 65, 2009
3DCC	Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties 分子名称: 5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION 著者 Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R. 登録日 2008-06-03 公開日 2009-03-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties Biochemistry, 48, 2009
3DCJ	Crystal structure of glycinamide formyltransferase (PurN) from Mycobacterium tuberculosis in complex with 5-methyl-5,6,7,8-tetrahydrofolic acid derivative 分子名称: CHLORIDE ION, MAGNESIUM ION, N-[4-({[(6S)-2-AMINO-4-HYDROXY-5-METHYL-5,6,7,8-TETRAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC ACID, ... 著者 Zhang, Z, Squire, C.J, Baker, E.N. 登録日 2008-06-03 公開日 2009-05-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of glycinamide ribonucleotide transformylase (PurN) from Mycobacterium tuberculosis reveal a novel dimer with relevance to drug discovery. J.Mol.Biol., 389, 2009
4KS8	PAK6 kinase domain in complex with sunitinib 分子名称: N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide, Serine/threonine-protein kinase PAK 6 著者 Gao, J, Boggon, T.J. 登録日 2013-05-17 公開日 2013-09-11 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Substrate and Inhibitor Specificity of the Type II p21-Activated Kinase, PAK6. Plos One, 8, 2013
3MNI	Human Carbonic Anhydrase II Mutant K170D 分子名称: Carbonic anhydrase 2, SODIUM ION, ZINC ION 著者 Domsic, J.F, McKenna, R. 登録日 2010-04-21 公開日 2010-07-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural and kinetic study of the extended active site for proton transfer in human carbonic anhydrase II. Biochemistry, 49, 2010
3DCV	Crystal structure of human Pim1 kinase complexed with 4-(4-hydroxy-3-methyl-phenyl)-6-phenylpyrimidin-2(1H)-one 分子名称: 4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(5H)-one, Proto-oncogene serine/threonine-protein kinase Pim-1 著者 Bellamacina, C.R, Shafer, C.M, Lindvall, M, Gesner, T.G, Yabannavar, A, Weiping, J, Song, L, Walter, A. 登録日 2008-06-04 公開日 2008-08-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 4-(1H-indazol-5-yl)-6-phenylpyrimidin-2(1H)-one analogs as potent CDC7 inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
3MNS	Investigation of global and local effects of radiation damage on porcine pancreatic elastase. Third stage of radiation damage 分子名称: Chymotrypsin-like elastase family member 1, SODIUM ION, SULFATE ION 著者 Petrova, T, Ginell, S, Kim, Y, Joachimiak, G, Joachimiak, A. 登録日 2010-04-22 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.497 Å) 主引用文献 X-ray-induced deterioration of disulfide bridges at atomic resolution. Acta Crystallogr.,Sect.D, 66, 2010
3MO6	Investigation of global and local effects of radiation damage on porcine pancreatic elastase. Sixth stage of radiation damage 分子名称: Chymotrypsin-like elastase family member 1, SODIUM ION, SULFATE ION 著者 Petrova, T, Ginell, S, Kim, Y, Joachimiak, G, Joachimiak, A. 登録日 2010-04-22 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 X-ray-induced deterioration of disulfide bridges at atomic resolution. Acta Crystallogr.,Sect.D, 66, 2010
3DD4	Structural Basis of KChIP4a Modulation of Kv4.3 Slow Inactivation 分子名称: CALCIUM ION, Kv channel-interacting protein 4 著者 Chai, J, Wang, H, Wang, K. 登録日 2008-06-05 公開日 2008-12-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural Insights into KChIP4a Modulation of Kv4.3 Inactivation. J.Biol.Chem., 284, 2009
4KNU	Copper nitrite reductase from Nitrosomonas europaea at pH 6.5 分子名称: CHLORIDE ION, COPPER (II) ION, GLYCEROL, ... 著者 Rosenzweig, A.C, Lawton, T.L, Sayavedra-Soto, L.A, Arp, D.J. 登録日 2013-05-10 公開日 2013-07-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Characterization of a nitrite reductase involved in nitrifier denitrification. J.Biol.Chem., 288, 2013

<568569570571572573574575576577578579580581582583>