3DCJ

Crystal structure of glycinamide formyltransferase (PurN) from Mycobacterium tuberculosis in complex with 5-methyl-5,6,7,8-tetrahydrofolic acid derivative

Summary for 3DCJ

Entry DOI	10.2210/pdb3dcj/pdb
Related	3DA8
Descriptor	Probable 5'-phosphoribosylglycinamide formyltransferase purN, N-[4-({[(6S)-2-AMINO-4-HYDROXY-5-METHYL-5,6,7,8-TETRAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC ACID, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	glycinamide formyltransferase, purn, transferase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	45895.38
Authors	Zhang, Z.,Squire, C.J.,Baker, E.N. (deposition date: 2008-06-03, release date: 2009-05-12, Last modification date: 2023-08-30)
Primary citation	Zhang, Z.,Caradoc-Davies, T.T.,Dickson, J.M.,Baker, E.N.,Squire, C.J. Structures of glycinamide ribonucleotide transformylase (PurN) from Mycobacterium tuberculosis reveal a novel dimer with relevance to drug discovery. J.Mol.Biol., 389:722-733, 2009 Cited by PubMed: 19394344 DOI: 10.1016/j.jmb.2009.04.044 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation