PDB: 20648 件ウェブページステータス検索Chemie searchBIRD

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4P6K	Crystal Structure of the Computationally Designed Transmembrane Metallotransporter with 4-bromophenylalanine in Lipidic Cubic Phase 分子名称: Computationally Designed Transporter of Zn(II) and Proton 著者 Joh, N.H, Acharya, R, DeGrado, W.F. 登録日 2014-03-25 公開日 2014-12-24 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.704 Å) 主引用文献 De novo design of a transmembrane Zn2+-transporting four-helix bundle. Science, 346, 2014
5DND	Crystal structure of the Asn-bound guinea pig L-asparaginase 1 catalytic domain active site mutant T116A 分子名称: 1,2-ETHANEDIOL, ASPARAGINE, L-asparaginase 著者 Schalk, A.M, Lavie, A. 登録日 2015-09-09 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Experimental Data in Support of a Direct Displacement Mechanism for Type I/II l-Asparaginases. J.Biol.Chem., 291, 2016
5DNE	Crystal structure of the Asn-bound guinea pig L-asparaginase 1 catalytic domain active site mutant K188M 分子名称: 1,2-ETHANEDIOL, ASPARAGINE, L-asparaginase 著者 Schalk, A.M, Lavie, A. 登録日 2015-09-10 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Experimental Data in Support of a Direct Displacement Mechanism for Type I/II l-Asparaginases. J.Biol.Chem., 291, 2016
4X8H	Crystal structure of E. coli Adenylate kinase P177A mutant 分子名称: Adenylate kinase 著者 Sauer-Eriksson, A.E, Kovermann, M, Aden, J, Grundstrom, C, Wolf-Watz, M, Sauer, U.H. 登録日 2014-12-10 公開日 2015-07-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for catalytically restrictive dynamics of a high-energy enzyme state. Nat Commun, 6, 2015
4X8L	Crystal structure of E. coli Adenylate kinase P177A mutant in complex with inhibitor Ap5a 分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ... 著者 Sauer-Eriksson, A.E, Kovermann, M, Aden, J, Grundstrom, C, Wolf-Watz, M, Sauer, U.H. 登録日 2014-12-10 公開日 2015-07-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for catalytically restrictive dynamics of a high-energy enzyme state. Nat Commun, 6, 2015
4X8O	Crystal structure of E. coli Adenylate kinase Y171W mutant in complex with inhibitor Ap5a 分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ... 著者 Sauer-Eriksson, A.E, Kovermann, M, Aden, J, Grundstrom, C, Wolf-Watz, M, Sauer, U.H. 登録日 2014-12-10 公開日 2015-07-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for catalytically restrictive dynamics of a high-energy enzyme state. Nat Commun, 6, 2015
5K2L	Crystal structure of LysM domain from Volvox carteri chitinase 分子名称: 1,2-ETHANEDIOL, Chitinase, lysozyme 著者 Kitaoku, Y, Numata, T, Fukamizo, T, Ohnuma, T. 登録日 2016-05-19 公開日 2017-02-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Chitin oligosaccharide binding to the lysin motif of a novel type of chitinase from the multicellular green alga, Volvox carteri. Plant Mol. Biol., 93, 2017
7KDZ	Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to TP-238 分子名称: 1,2-ETHANEDIOL, 6-{4-[3-(dimethylamino)propoxy]phenyl}-2-(methylsulfonyl)-N-[3-(1H-pyrazol-1-yl)propyl]pyrimidin-4-amine, Nucleosome-remodeling factor subunit BPTF 著者 Chan, A, Schonbrunn, E. 登録日 2020-10-09 公開日 2020-12-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development Organic & Biomolecular Chemistry, 18(27), 2020
7LML	Receptor for Advanced Glycation End Products VC1 domain in complex with 3-(3-(((3-(4-Carboxyphenoxy)benzyl)oxy)methyl)phenyl)-1H-indole-2-carboxylic acid 分子名称: 6-iodanyl-1~{H}-indole-2-carboxylic acid, ACETATE ION, Advanced glycosylation end product-specific receptor, ... 著者 Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J. 登録日 2021-02-05 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors. Proteins, 89, 2021
5K79	Structure and anti-HIV activity of CYT-CVNH, a new cyanovirin-n homolog 分子名称: 1,2-ETHANEDIOL, Cyanovirin-N domain protein, DI(HYDROXYETHYL)ETHER 著者 Matei, E, Basu, R, Furey, W, Shi, J, Calnan, C, Aiken, C, Gronenborn, A.M. 登録日 2016-05-25 公開日 2016-07-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure and Glycan Binding of a New Cyanovirin-N Homolog. J.Biol.Chem., 291, 2016
4LAD	Crystal Structure of the Ube2g2:RING-G2BR complex 分子名称: E3 ubiquitin-protein ligase AMFR, OXALATE ION, Ubiquitin-conjugating enzyme E2 G2, ... 著者 Liang, Y.-H, Li, J, Das, R, Byrd, R.A, Ji, X. 登録日 2013-06-19 公開日 2013-08-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine. Embo J., 32, 2013
7LMW	Receptor for Advanced Glycation End Products VC1 domain in complex with 3-(3-((4-(4-carboxyphenoxy)benzyl)oxy)phenyl)-1H-indole-2-carboxylic acid 分子名称: 7-methyl-3-(1~{H}-pyrazol-4-yl)-1~{H}-indole-2-carboxylic acid, ACETATE ION, Advanced glycosylation end product-specific receptor, ... 著者 Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J. 登録日 2021-02-06 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors. Proteins, 89, 2021
6IHG	N terminal domain of Mycobacterium avium complex Lon protease 分子名称: Lon protease 著者 Chen, X.Y, Zhang, S.J, Bi, F.K, Guo, C.Y, Yao, H.W, Lin, D.H. 登録日 2018-09-29 公開日 2019-08-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.397 Å) 主引用文献 Crystal structure of the N domain of Lon protease from Mycobacterium avium complex. Protein Sci., 28, 2019
7ALR	Crystal structure of TD1-gatorbulin1 complex 分子名称: (2~{R})-2-oxidanyl-2-[(6~{S},9~{S},12~{S},15~{S},17~{S})-6,10,12,17-tetramethyl-3-methylidene-7-oxidanyl-2,5,8,11,14-pentakis(oxidanylidene)-13-oxa-1,4,7,10-tetrazabicyclo[13.3.0]octadecan-9-yl]ethanamide, Designed Ankyrin Repeat Protein (DARPIN) D1, GLYCEROL, ... 著者 Oliva, M.A, Diaz, J.F. 登録日 2020-10-07 公開日 2021-03-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site. Proc.Natl.Acad.Sci.USA, 118, 2021
3L1X	Crystal Structure of U-box Domain of Human E4B Ubiquitin Ligase 分子名称: Ubiquitin conjugation factor E4 B 著者 Benirschke, R, Thompson, J.R, Mer, G. 登録日 2009-12-14 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4. Structure, 18, 2010
3L1Z	Crystal structure of the U-BOX domain of human E4B ubiquitin ligase in complex with UBCH5C E2 ubiquitin conjugating enzyme 分子名称: Ubiquitin conjugation factor E4 B, Ubiquitin-conjugating enzyme E2 D3 著者 Benirschke, R, Thompson, J.R, Mer, G. 登録日 2009-12-14 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.17 Å) 主引用文献 Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4. Structure, 18, 2010
3L1Y	Crystal structure of human UBC4 E2 conjugating enzyme 分子名称: Ubiquitin-conjugating enzyme E2 D2 著者 Benirschke, R, Thompson, J.R, Mer, G. 登録日 2009-12-14 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4. Structure, 18, 2010
3LE8	Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.70 Angstrom resolution in complex with 2-(2-((benzofuran-2-carboxamido)methyl)-5-methoxy-1H-indol-1-yl)acetic acid 分子名称: 1,2-ETHANEDIOL, 2-(2-((benzofuran-2-carboxamido)methyl)-5-methoxy-1H-indol-1-yl)acetic acid, ETHANOL, ... 著者 Silvestre, H.L, Hung, A.W, Sledz, P, Ciulli, A, Blundell, T.L, Abell, C. 登録日 2010-01-14 公開日 2010-04-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Optimization of the interligand overhauser effect for fragment linking: application to inhibitor discovery against Mycobacterium tuberculosis pantothenate synthetase. J.Am.Chem.Soc., 132, 2010
3L9Q	Crystal structure of human polymerase alpha-primase p58 iron-sulfur cluster domain 分子名称: DNA primase large subunit, IRON/SULFUR CLUSTER, SULFATE ION 著者 Vaithiyalingam, S, Eichman, B.F, Chazin, W.J. 登録日 2010-01-05 公開日 2010-07-14 最終更新日 2011-11-16 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase. Proc.Natl.Acad.Sci.USA, 107, 2010
4XCP	Fatty Acid and Retinol binding protein Na-FAR-1 from Necator americanus 分子名称: Nematode fatty acid retinoid binding protein, PALMITIC ACID 著者 Gabrielsen, M, Rey-Burusco, M.F, Ibanez-Shimabukuro, M, Griffiths, K, Kennedy, M.W, Corsico, B, Smith, B.O. 登録日 2014-12-18 公開日 2015-09-16 最終更新日 2017-08-30 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Diversity in the structures and ligand-binding sites of nematode fatty acid and retinol-binding proteins revealed by Na-FAR-1 from Necator americanus. Biochem.J., 471, 2015
8HIA	Structure of transforming growth factor beta induced protein (TGFBIp) G623R fibril 分子名称: Transforming growth factor-beta-induced protein ig-h3 著者 Low, J.Y.K, Pervushin, K. 登録日 2022-11-19 公開日 2023-07-26 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Release of frustration drives corneal amyloid disaggregation by brain chaperone. Commun Biol, 6, 2023
4KQO	Crystal structure of penicillin-binding protein 3 from pseudomonas aeruginosa in complex with piperacillin 分子名称: CHLORIDE ION, GLYCEROL, IMIDAZOLE, ... 著者 Nettleship, J.E, Stuart, D.I, Owens, R.J, Ren, J. 登録日 2013-05-15 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Binding of (5S)-Penicilloic Acid to Penicillin Binding Protein 3. Acs Chem.Biol., 8, 2013
8HJT	Crystal Structure of Intracellular B30.2 Domain of VpBTN3 and VpBTN2 in Complex with HMBPP 分子名称: (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Butyrophylin 3, ... 著者 Yang, Y.Y, Shen, P.P, Li, X, Yi, S.M, Zhang, M.T, Huang, J.-W, Chen, C.-C, Guo, R.-T. 登録日 2022-11-23 公開日 2023-09-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. Nature, 621, 2023
3MOS	The structure of human Transketolase 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, SODIUM ION, ... 著者 Parthier, C, Tittmann, K. 登録日 2010-04-23 公開日 2010-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 The crystal structure of human transketolase and new insights into its mode of action. J.Biol.Chem., 285, 2010
4KQR	CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH (5S)-Penicilloic Acid 分子名称: (2S,4S)-2-[(R)-carboxy{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CHLORIDE ION, GLYCEROL, ... 著者 Nettleship, J.E, Stuart, D.I, Owens, R.J, Ren, J. 登録日 2013-05-15 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Binding of (5S)-Penicilloic Acid to Penicillin Binding Protein 3. Acs Chem.Biol., 8, 2013

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