Crystal structure of the Asn-bound guinea pig L-asparaginase 1 catalytic domain active site mutant K188M

Summary for 5DNE

Related4R8K 4R8L 5DNC 5DND
DescriptorL-asparaginase, ASPARAGINE, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsasparaginase, hydrolase
Biological sourceCavia porcellus (Guinea pig)
Total number of polymer chains4
Total molecular weight254634.12
Schalk, A.M.,Lavie, A. (deposition date: 2015-09-10, release date: 2016-01-13, Last modification date: 2016-03-23)
Primary citation
Schalk, A.M.,Antansijevic, A.,Caffrey, M.,Lavie, A.
Experimental Data in Support of a Direct Displacement Mechanism for Type I/II l-Asparaginases.
J.Biol.Chem., 291:5088-5100, 2016
PubMed: 26733195 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M115.699884
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.24120 0.3% 4.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-28