PDB: 45953 件ウェブページステータス検索Chemie searchBIRD

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8WB0	De novo transcribing complex 17 (TC17), the early elongation complex with Pol II positioned 17nt downstream of TSS 分子名称: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. 登録日 2023-09-08 公開日 2023-12-06 最終更新日 2024-01-03 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 Structural visualization of transcription initiation in action. Science, 382, 2023
8WAU	De novo transcribing complex 11 (TC11), the early elongation complex with Pol II positioned 11nt downstream of TSS 分子名称: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. 登録日 2023-09-08 公開日 2023-12-06 最終更新日 2024-01-03 実験手法 ELECTRON MICROSCOPY (2.78 Å) 主引用文献 Structural visualization of transcription initiation in action. Science, 382, 2023
7U5C	Cryo-EM structure of human CST bound to DNA polymerase alpha-primase in a recruitment state 分子名称: CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... 著者 Cai, S.W, Zinder, J.C, Svetlov, V, Bush, M.W, Nudler, E, Walz, T, de Lange, T. 登録日 2022-03-02 公開日 2022-05-18 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Cryo-EM structure of the human CST-Pol alpha /primase complex in a recruitment state. Nat.Struct.Mol.Biol., 29, 2022
8WAV	De novo transcribing complex 12 (TC12), the early elongation complex with Pol II positioned 12nt downstream of TSS 分子名称: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. 登録日 2023-09-08 公開日 2023-12-06 最終更新日 2024-01-03 実験手法 ELECTRON MICROSCOPY (2.72 Å) 主引用文献 Structural visualization of transcription initiation in action. Science, 382, 2023
8WAZ	De novo transcribing complex 16 (TC16), the early elongation complex with Pol II positioned 16nt downstream of TSS 分子名称: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. 登録日 2023-09-08 公開日 2023-12-06 最終更新日 2024-01-03 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 Structural visualization of transcription initiation in action. Science, 382, 2023
8WAX	De novo transcribing complex 14 (TC14), the early elongation complex with Pol II positioned 14nt downstream of TSS 分子名称: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. 登録日 2023-09-08 公開日 2023-12-06 最終更新日 2024-01-03 実験手法 ELECTRON MICROSCOPY (2.75 Å) 主引用文献 Structural visualization of transcription initiation in action. Science, 382, 2023
5D4D	Crystal structure of Thermus thermophilus product complex for transcription initiation with NAD and CTP 分子名称: ADENOSINE MONOPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Zhang, Y, Ebright, R.H. 登録日 2015-08-07 公開日 2016-07-06 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA. Nature, 535, 2016
8WAY	De novo transcribing complex 15 (TC15), the early elongation complex with Pol II positioned 15nt downstream of TSS 分子名称: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. 登録日 2023-09-08 公開日 2023-12-06 最終更新日 2024-01-03 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Structural visualization of transcription initiation in action. Science, 382, 2023
8WAW	De novo transcribing complex 13 (TC13), the early elongation complex with Pol II positioned 13nt downstream of TSS 分子名称: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. 登録日 2023-09-08 公開日 2023-12-06 最終更新日 2024-01-03 実験手法 ELECTRON MICROSCOPY (3.02 Å) 主引用文献 Structural visualization of transcription initiation in action. Science, 382, 2023
5D4E	Crystal structure of Thermus thermophilus product complex for transcription initiation with 3'-dephosphate-CoA and CTP 分子名称: CYTIDINE-5'-MONOPHOSPHATE, DEPHOSPHO COENZYME A, DIPHOSPHATE, ... 著者 Zhang, Y, Ebright, R.H. 登録日 2015-08-07 公開日 2016-07-06 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA. Nature, 535, 2016
3HOV	Complete RNA polymerase II elongation complex II 分子名称: 5'-D(*AP*GP*CP*TP*CP*AP*A*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*T*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*CP*A)-3', ... 著者 Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. 登録日 2009-06-03 公開日 2009-07-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
6K4Y	CryoEM structure of sigma appropriation complex 分子名称: 10 kDa anti-sigma factor, DNA (60-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Shi, J, Wen, A, Feng, Y. 登録日 2019-05-27 公開日 2019-08-07 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.79 Å) 主引用文献 Structural basis of sigma appropriation. Nucleic Acids Res., 47, 2019
4OQM	Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with F-ARA-EdU 分子名称: 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethynylpyrimidine-2,4(1H,3H)-dione, SULFATE ION, Thymidine kinase 著者 Pernot, L, Neef, A.B, Westermaier, Y, Perozzo, R, Luedtke, N, Scapozza, L. 登録日 2014-02-10 公開日 2014-08-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with F-ARA-EdU To be Published
4OQL	Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with dF-EdU 分子名称: 2'-deoxy-5-ethynyl-2',2'-difluorouridine, SULFATE ION, Thymidine kinase 著者 Pernot, L, Neef, A.B, Westermaier, Y, Perozzo, R, Luedtke, N, Scapozza, L. 登録日 2014-02-10 公開日 2014-08-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with dF-EdU To be Published
3HOW	Complete RNA polymerase II elongation complex III with a T-U mismatch and a frayed RNA 3'-uridine 分子名称: 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*U)-3', ... 著者 Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. 登録日 2009-06-03 公開日 2009-07-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
3HOX	Complete RNA polymerase II elongation complex V 分子名称: 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*AP*AP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*U)-3', ... 著者 Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. 登録日 2009-06-03 公開日 2009-07-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
3HOZ	Complete RNA polymerase II elongation complex IV with a T-U mismatch and a frayed RNA 3'-guanine 分子名称: 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*CP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*G)-3', ... 著者 Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. 登録日 2009-06-03 公開日 2009-07-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
3HOU	Complete RNA polymerase II elongation complex I with a T-U mismatch 分子名称: 5'-D(*A*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*CP*A*AP*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*U*UP*CP*GP*AP*CP*CP*AP*GP*GP*CP*U)-3', ... 著者 Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. 登録日 2009-06-03 公開日 2009-07-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
3HOY	Complete RNA polymerase II elongation complex VI 分子名称: 5'-D(*CP*CP*AP*AP*GP*CP*TP*CP*AP*AP*G*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*TP*AP*CP*TP*AP*GP*TP*AP*CP*TP*GP*CP*C)-3', 5'-D(*CP*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*AP*GP*TP*AP*AP*AP*CP*TP*AP*GP*TP*AP*TP*T*GP*AP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP*T)-3', 5'-R(*UP*AP*UP*AP*UP*GP*CP*A*UP*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*A)-3', ... 著者 Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. 登録日 2009-06-03 公開日 2009-07-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
5FUR	Structure of human TFIID-IIA bound to core promoter DNA 分子名称: SUPER CORE PROMOTER, TATA-BOX-BINDING PROTEIN, TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1, ... 著者 Louder, R.K, He, Y, Lopez-Blanco, J.R, Fang, J, Chacon, P, Nogales, E. 登録日 2016-01-29 公開日 2016-04-06 最終更新日 2017-08-02 実験手法 ELECTRON MICROSCOPY (8.5 Å) 主引用文献 Structure of Promoter-Bound TFIID and Model of Human Pre-Initiation Complex Assembly. Nature, 531, 2016
7UIO	Mediator-PIC Early (Composite Model) 分子名称: ALANINE, ASPARTIC ACID, DNA (37-MER), ... 著者 Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. 登録日 2022-03-29 公開日 2023-03-01 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol.Cell, 83, 2023
7KEF	RNA polymerase II elongation complex with unnatural base dTPT3, rNaM in swing state 分子名称: (1S)-1,4-anhydro-1-(3-methoxynaphthalen-2-yl)-5-O-phosphono-D-ribitol, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... 著者 Oh, J, Wang, D. 登録日 2020-10-10 公開日 2021-06-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.89 Å) 主引用文献 Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II. Nat.Chem.Biol., 17, 2021
7KEE	RNA polymerase II elongation complex with unnatural base dTPT3, rNaMTP bound to E-site 分子名称: (1S)-1,4-anhydro-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-1-(3-methoxynaphthalen-2-yl)-D-ribitol, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... 著者 Oh, J, Wang, D. 登録日 2020-10-10 公開日 2021-06-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II. Nat.Chem.Biol., 17, 2021
6KQD	Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 3 nt 分子名称: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), ... 著者 Zhang, Y, Li, L, Ebright, R.H. 登録日 2019-08-17 公開日 2020-03-11 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
4UQO	RADA C-TERMINAL ATPASE DOMAIN FROM PYROCOCCUS FURIOSUS BOUND TO ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA REPAIR AND RECOMBINATION PROTEIN RADA, MAGNESIUM ION, ... 著者 Marsh, M.E, Ehebauer, M.T, Scott, D, Abell, C, Blundell, T.L, Hyvonen, M. 登録日 2014-06-24 公開日 2015-01-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 ATP Half-Sites in Rada and Rad51 Recombinases Bind Nucleotides FEBS Open Bio, 6, 2016

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