4OQM

Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with F-ARA-EdU

Summary for 4OQM

• Entry DOI: 10.2210/pdb4oqm/pdb
• Related: 4OQL 4OQN 4OQX
• Descriptor: Thymidine kinase, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethynylpyrimidine-2,4(1H,3H)-dione, SULFATE ION, ... (4 entities in total)
• Functional Keywords: dna synthesis, thymidine kinase, atp-binding, nucleotide-binding, transferase, 5-ethynyluridine nucleoside derivative
• Biological source: Human herpesvirus 1 (HHV-1)
• Total number of polymer chains: 2
• Total formula weight: 72933.34

Authors

Pernot, L.,Neef, A.B.,Westermaier, Y.,Perozzo, R.,Luedtke, N.,Scapozza, L. (deposition date: 2014-02-10, release date: 2014-08-13, Last modification date: 2023-09-20)

• Primary citation: Pernot, L.,Neef, A.B.,Westermaier, Y.,Perozzo, R.,Luedtke, N.,Scapozza, L.; Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with F-ARA-EdU; To be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)