PDB: 14265 件ウェブページステータス検索Chemie searchBIRD

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4AEX	HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 2.4 ANGSTROM in a primitive orthorhombic space group 分子名称: PHOSPHATE ION, RNA-DIRECTED RNA POLYMERASE 著者 Caillet-Saguy, C, Bressanelli, S. 登録日 2012-01-12 公開日 2012-05-02 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Two Crucial Early Steps in RNA Synthesis by the Hepatitis C Virus Polymerase Involve a Dual Role of Residue 405. J.Virol., 86, 2012
4BJI	Sfc1-DBD 分子名称: TRANSCRIPTION FACTOR TAU SUBUNIT SFC1 著者 Taylor, N.M.I, Baudin, F, von Scheven, G, Muller, C.W. 登録日 2013-04-18 公開日 2013-07-31 最終更新日 2013-11-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 RNA Polymerase III-Specific General Transcription Factor Iiic Contains a Heterodimer Resembling Tfiif RAP30/RAP74. Nucleic Acids Res., 41, 2013
4BJJ	Sfc1-Sfc7 dimerization module 分子名称: MERCURY (II) ION, TRANSCRIPTION FACTOR TAU SUBUNIT SFC1, TRANSCRIPTION FACTOR TAU SUBUNIT SFC7 著者 Taylor, N.M.I, Baudin, F, von Scheven, G, Muller, C.W. 登録日 2013-04-18 公開日 2013-07-31 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 RNA Polymerase III-Specific General Transcription Factor Iiic Contains a Heterodimer Resembling Tfiif RAP30/RAP74. Nucleic Acids Res., 41, 2013
3E51	Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor 分子名称: N-{3-[5-hydroxy-2-(3-methylbutyl)-3-oxo-6-pyrrolidin-1-yl-2,3-dihydropyridazin-4-yl]-1,1-dioxido-2H-1,2,4-benzothiadiazin-7-yl}methanesulfonamide, RNA-directed RNA polymerase 著者 Han, Q, Showalter, R.E, Zhao, Q, Kissinger, C.R. 登録日 2008-08-12 公開日 2009-08-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 5: Exploration of pyridazinones containing 6-amino-substituents. Bioorg.Med.Chem.Lett., 18, 2008
1FQZ	NMR VALIDATED MODEL OF DOMAIN IIID OF HEPATITIS C VIRUS INTERNAL RIBOSOME ENTRY SITE 分子名称: HEPATITIS C VIRUS IRES DOMAIN IIID 著者 Klinck, R, Westhof, E, Walker, S, Afshar, M, Collier, A, Aboul-ela, F. 登録日 2000-09-07 公開日 2001-01-17 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A potential RNA drug target in the hepatitis C virus internal ribosomal entry site. RNA, 6, 2000
1ZH5	Structural basis for recognition of UUUOH 3'-terminii of nascent RNA pol III transcripts by La autoantigen 分子名称: 5'-R(*UP*GP*CP*UP*GP*UP*UP*UP*U)-3', Lupus La protein, SULFATE ION 著者 Teplova, M, Yuan, Y.R, Ilin, S, Malinina, L, Phan, A.T, Teplov, A, Patel, D.J. 登録日 2005-04-22 公開日 2006-01-17 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen. Mol.Cell, 21, 2006
3AVV	Structure of viral RNA polymerase complex 3 分子名称: CALCIUM ION, Elongation factor Ts, Elongation factor Tu, ... 著者 Takeshita, D, Tomita, K. 登録日 2011-03-08 公開日 2012-01-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.119 Å) 主引用文献 Molecular basis for RNA polymerization by Q beta replicase Nat.Struct.Mol.Biol., 19, 2012
3AVY	Structure of viral RNA polymerase complex 6 分子名称: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, Elongation factor Ts, ... 著者 Takeshita, D, Tomita, K. 登録日 2011-03-08 公開日 2012-01-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.616 Å) 主引用文献 Molecular basis for RNA polymerization by Q beta replicase Nat.Struct.Mol.Biol., 19, 2012
2MT4	Solution structure of the N-terminal domain of NUSA from B. Subtilis 分子名称: Transcription termination/antitermination protein NusA 著者 Mobli, M, Lewis, P.J. 登録日 2014-08-12 公開日 2015-02-18 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 RNA polymerase-induced remodelling of NusA produces a pause enhancement complex. Nucleic Acids Res., 43, 2015
3FQL	Hepatitis C virus polymerase NS5B (CON1 1-570) with HCV-796 inhibitor 分子名称: 5-cyclopropyl-2-(4-fluorophenyl)-6-[(2-hydroxyethyl)(methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide, GLYCEROL, RNA-directed RNA polymerase 著者 Harris, S.F, Wong, A. 登録日 2009-01-07 公開日 2009-02-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Slow binding inhibition and mechanism of resistance of non-nucleoside polymerase inhibitors of hepatitis C virus. J.Biol.Chem., 284, 2009
3FQK	Hepatitis C virus polymerase NS5B (BK 1-570) with HCV-796 inhibitor 分子名称: 5-cyclopropyl-2-(4-fluorophenyl)-6-[(2-hydroxyethyl)(methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide, RNA-directed RNA polymerase 著者 Harris, S.F, Wong, A. 登録日 2009-01-07 公開日 2009-02-24 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Slow binding inhibition and mechanism of resistance of non-nucleoside polymerase inhibitors of hepatitis C virus. J.Biol.Chem., 284, 2009
1SH3	Crystal Structure of Norwalk Virus Polymerase (MgSO4 crystal form) 分子名称: MAGNESIUM ION, RNA Polymerase 著者 Ng, K.K, Pendas-Franco, N, Rojo, J, Boga, J.A, Machin, A, Alonso, J.M, Parra, F. 登録日 2004-02-24 公開日 2004-03-09 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Crystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleft. J.Biol.Chem., 279, 2004
3HKY	HCV NS5B polymerase genotype 1b in complex with 1,5 benzodiazepine 6 分子名称: (11S)-10-[(2,5-dimethyl-1,3-oxazol-4-yl)carbonyl]-11-{2-fluoro-4-[(2-methylprop-2-en-1-yl)oxy]phenyl}-3,3-dimethyl-2,3,4,5,10,11-hexahydrothiopyrano[3,2-b][1,5]benzodiazepin-6-ol 1,1-dioxide, CHLORIDE ION, RNA-directed RNA polymerase, ... 著者 Nyanguile, O, De Bondt, H.L. 登録日 2009-05-26 公開日 2010-05-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 1a/1b subtype profiling of nonnucleoside polymerase inhibitors of hepatitis C virus J.Virol., 84, 2010
1YTY	Structural basis for recognition of UUUOH 3'-terminii of nascent RNA pol III transcripts by La autoantigen 分子名称: 5'-R(*UP*GP*CP*UP*GP*UP*UP*UP*U)-3', Lupus La protein 著者 Teplova, M, Yuan, Y.R, Ilin, S, Malinina, L, Phan, A.T, Teplov, A, Patel, D.J. 登録日 2005-02-11 公開日 2006-01-17 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen. Mol.Cell, 21, 2006
4GP7	Polynucleotide kinase 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CITRIC ACID, MAGNESIUM ION, ... 著者 Wang, L.K, Das, U, Smith, P, Shuman, S. 登録日 2012-08-20 公開日 2012-11-14 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system. Rna, 18, 2012
4GP6	Polynucleotide kinase 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Metallophosphoesterase 著者 Wang, L.K, Das, U, Smith, P, Shuman, S. 登録日 2012-08-20 公開日 2012-11-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system. Rna, 18, 2012
2NAX	Structure of CCHC zinc finger domain of Pcf11 分子名称: Protein PCF11, ZINC ION 著者 Yang, F, Varani, G. 登録日 2016-01-12 公開日 2016-11-23 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The C terminus of Pcf11 forms a novel zinc-finger structure that plays an essential role in mRNA 3'-end processing. RNA, 23, 2017
2LLI	Low resolution structure of RNA-binding subunit of the TRAMP complex 分子名称: Protein AIR2, ZINC ION 著者 Holub, P, Lalakova, J, Cerna, H, Sarazova, M, Pasulka, J, Hrazdilova, K, Arce, M.S, Stefl, R, Vanacova, S. 登録日 2011-11-10 公開日 2012-03-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Air2p is critical for the assembly and RNA-binding of the TRAMP complex and the KOW domain of Mtr4p is crucial for exosome activation. Nucleic Acids Res., 40, 2012
1JZC	THE SOLUTION STRUCTURE OF THE MUTANT 5'AUG3' TRILOOP IN THE RNA PROMOTER REGION OF THE BROME MOSAIC VIRUS GENOMIC (+)-RNA 分子名称: 5'-R(*GP*GP*UP*GP*CP*AP*UP*GP*GP*CP*AP*CP*C)-3' 著者 Kim, C.-H, Kao, C.C. 登録日 2001-09-14 公開日 2003-10-07 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A mutant viral RNA promoter with an altered conformation retains efficient recognition by a viral RNA replicase through a solution-exposed adenine RNA, 7, 2001
8BYQ	RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W) 分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... 著者 Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. 登録日 2022-12-14 公開日 2023-05-03 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Mol.Cell, 83, 2023
8BVW	RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W) 分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... 著者 Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. 登録日 2022-12-20 公開日 2023-05-03 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Mol.Cell, 83, 2023
6KV5	Structure of influenza D virus apo polymerase 分子名称: Polymerase 3, Polymerase PB2, RNA-directed RNA polymerase catalytic subunit 著者 Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. 登録日 2019-09-03 公開日 2019-10-02 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Structural insight into RNA synthesis by influenza D polymerase. Nat Microbiol, 4, 2019
8BZ1	RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W) 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. 登録日 2022-12-14 公開日 2023-05-03 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Mol.Cell, 83, 2023
6EVJ	Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter and capped RNA primer 分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(GDM))-R(P*AP*AP*U)-3'), ... 著者 Pflug, A, Cusack, S. 登録日 2017-11-01 公開日 2017-12-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors. Nucleic Acids Res., 46, 2018
4CHE	Crystal structure of the putative cap-binding domain of the PB2 subunit of Thogoto virus polymerase 分子名称: POLYMERASE BASIC PROTEIN 2 著者 Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S. 登録日 2013-12-01 公開日 2014-02-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains. Plos One, 9, 2014

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