PDB: 19260 件ウェブページステータス検索Chemie searchBIRD

---

3KN0	Structure of BACE bound to SCH708236 分子名称: 3-[2-(3-{[(furan-2-ylmethyl)(methyl)amino]methyl}phenyl)ethyl]pyridin-2-amine, Beta-secretase 1, L(+)-TARTARIC ACID 著者 Strickland, C, Wang, Y. 登録日 2009-11-11 公開日 2010-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Application of Fragment-Based NMR Screening, X-ray Crystallography, Structure-Based Design, and Focused Chemical Library Design to Identify Novel muM Leads for the Development of nM BACE-1 (beta-Site APP Cleaving Enzyme 1) Inhibitors. J.Med.Chem., 53, 2010
3L06	Crystal structure of N-acetyl-L-ornithine transcarbamylase E92V mutant complexed with carbamyl phosphate and N-succinyl-L-norvaline 分子名称: N-(3-CARBOXYPROPANOYL)-L-NORVALINE, N-acetylornithine carbamoyltransferase, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ... 著者 Shi, D, Yu, X, Allewell, N.M, Tuchman, M. 登録日 2009-12-09 公開日 2010-03-31 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 A single mutation in the active site swaps the substrate specificity of N-acetyl-L-ornithine transcarbamylase and N-succinyl-L-ornithine transcarbamylase. Protein Sci., 16, 2007
3L31	Crystal structure of the CBS and DRTGG domains of the regulatory region of Clostridium perfringens pyrophosphatase complexed with the inhibitor, AMP 分子名称: ADENOSINE MONOPHOSPHATE, Probable manganase-dependent inorganic pyrophosphatase 著者 Tuominen, H, Salminen, A, Oksanen, E, Jamsen, J, Heikkila, O, Lehtio, L, Magretova, N.N, Goldman, A, Baykov, A.A, Lahti, R. 登録日 2009-12-16 公開日 2010-04-21 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structures of the CBS and DRTGG Domains of the Regulatory Region of Clostridiumperfringens Pyrophosphatase Complexed with the Inhibitor, AMP, and Activator, Diadenosine Tetraphosphate. J.Mol.Biol., 2010
3L1E	Bovine AlphaA crystallin Zinc Bound 分子名称: Alpha-crystallin A chain, GLYCEROL, ZINC ION 著者 Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. 登録日 2009-12-11 公開日 2010-05-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Sci., 19, 2010
3L3V	Structure of HIV-1 integrase core domain in complex with sucrose 分子名称: CADMIUM ION, POL polyprotein, SULFATE ION, ... 著者 Wielens, J, Chalmers, D.K, Scanlon, M.J, Parker, M.W. 登録日 2009-12-18 公開日 2010-03-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the HIV-1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding site Febs Lett., 584, 2010
3L4M	Crystal Structure of the MauG/pre-Methylamine Dehydrogenase Complex. 分子名称: ACETATE ION, CALCIUM ION, HEME C, ... 著者 Jensen, L.M.R, Wilmot, C.M. 登録日 2009-12-21 公開日 2010-03-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 In crystallo posttranslational modification within a MauG/pre-methylamine dehydrogenase complex. Science, 327, 2010
3L3U	Crystal structure of the HIV-1 integrase core domain to 1.4A 分子名称: POL polyprotein, SULFATE ION 著者 Wielens, J, Chalmers, D.K, Scanlon, M.J, Parker, M.W. 登録日 2009-12-17 公開日 2010-03-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of the HIV-1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding site. Febs Lett., 584, 2010
3KPM	Crystal Structure of HLA B*4402 in complex with EEYLKAWTF, a mimotope 分子名称: Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ... 著者 Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J. 登録日 2009-11-16 公開日 2009-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 T cell allorecognition via molecular mimicry. Immunity, 31, 2009
3KQN	Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism 分子名称: 5'-D(*TP*TP*TP*TP*TP*T)-3', ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... 著者 Gu, M, Rice, C.M. 登録日 2009-11-17 公開日 2010-01-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism. Proc.Natl.Acad.Sci.USA, 107, 2010
3KQU	Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism 分子名称: 5'-D(*T*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... 著者 Gu, M, Rice, C.M. 登録日 2009-11-17 公開日 2010-01-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Inaugural Article: Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism. Proc.Natl.Acad.Sci.USA, 107, 2010
3KQO	Crystal Structure of hPNMT in Complex AdoHcy and 6-Chloropurine 分子名称: 6-chloro-9H-purine, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Drinkwater, N, Martin, J.L. 登録日 2009-11-17 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors. Biochem.J., 431, 2010
3KR1	Crystal Structure of hPNMT in Complex AdoHcy and 5-chloro-1H-benzo[d]imidazol-2-amine 分子名称: 6-chloro-1H-benzimidazol-2-amine, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Drinkwater, N, Martin, J.L. 登録日 2009-11-17 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors. Biochem.J., 431, 2010
3KS5	Crystal structure of Putative glycerophosphoryl diester phosphodiesterase (17743486) from AGROBACTERIUM TUMEFACIENS str. C58 (Dupont) at 2.05 A resolution 分子名称: 1,2-ETHANEDIOL, ACETATE ION, FE (III) ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2009-11-20 公開日 2009-12-08 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of Putative glycerophosphoryl diester phosphodiesterase (17743486) from AGROBACTERIUM TUMEFACIENS str. C58 (Dupont) at 2.05 A resolution To be published
3KSD	Crystal Structure of C151S+H178N mutant of Glyceraldehyde-3-phosphate dehydrogenase 1 (GAPDH1) from Staphylococcus aureus MRSA252 complexed with NAD at 2.2 angstrom resolution 分子名称: Glyceraldehyde-3-phosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Mukherjee, S, Dutta, D, Saha, B, Das, A.K. 登録日 2009-11-22 公開日 2010-08-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 1 from methicillin-resistant Staphylococcus aureus MRSA252 provides novel insights into substrate binding and catalytic mechanism. J.Mol.Biol., 401, 2010
3KSS	Structure and Mechanism of the Heavy Metal Transporter CusA 分子名称: COPPER (I) ION, Cation efflux system protein cusA 著者 Su, C.-C. 登録日 2009-11-23 公開日 2010-09-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.88 Å) 主引用文献 Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport. Nature, 467, 2010
3KTH	Structure of ClpP from Bacillus subtilis in orthorombic crystal form 分子名称: ATP-dependent Clp protease proteolytic subunit 著者 Lee, B.-G, Brotz-Oesterhelt, H, Song, H.K. 登録日 2009-11-25 公開日 2010-03-23 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism Nat.Struct.Mol.Biol., 17, 2010
3KRZ	Crystal Structure of the Thermostable NADH4-bound old yellow enzyme from Thermoanaerobacter pseudethanolicus E39 分子名称: 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FLAVIN MONONUCLEOTIDE, NADH:flavin oxidoreductase/NADH oxidase 著者 Adalbjornsson, B.V, Toogood, H.S, Leys, D, Scrutton, N.S. 登録日 2009-11-20 公開日 2009-12-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Biocatalysis with thermostable enzymes: structure and properties of a thermophilic 'ene'-reductase related to old yellow enzyme. Chembiochem, 11, 2010
3KV3	Crystal structure of C151S mutant of Glyceraldehyde-3-phosphate dehydrogenase 1 (GAPDH 1)from methicillin resistant Staphylococcus aureus MRSA252 complexed with NAD and G3P 分子名称: 3-PHOSPHOGLYCERIC ACID, GAPDH, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Mukherjee, S, Dutta, D, Saha, B, Das, A.K. 登録日 2009-11-29 公開日 2010-08-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 1 from methicillin-resistant Staphylococcus aureus MRSA252 provides novel insights into substrate binding and catalytic mechanism. J.Mol.Biol., 401, 2010
3KVV	Trapping of an oxocarbenium ion intermediate in UP crystals 分子名称: 1,4-anhydro-D-erythro-pent-1-enitol, 5-FLUOROURACIL, SULFATE ION, ... 著者 Paul, D, O'Leary, S, Rajashankar, K, Bu, W, Toms, A, Settembre, E, Sanders, J, Begley, T.P, Ealick, S.E. 登録日 2009-11-30 公開日 2010-04-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Glycal formation in crystals of uridine phosphorylase. Biochemistry, 49, 2010
3KWR	Crystal structure of Putative RNA-binding protein (NP_785364.1) from LACTOBACILLUS PLANTARUM at 1.45 A resolution 分子名称: GLYCEROL, Putative RNA-binding protein, SULFATE ION 著者 Joint Center for Structural Genomics (JCSG) 登録日 2009-12-01 公開日 2009-12-22 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of Putative RNA-binding protein (NP_785364.1) from Lactobacillus plantarum at 1.45 A resolution To be published
3KT4	Crystal structure of Tpa1 from Saccharomyces cerevisiae, a component of the messenger ribonucleoprotein complex 分子名称: FE (III) ION, PKHD-type hydroxylase TPA1 著者 Kim, H.S, Kim, H.L, Kim, K.H, Kim, D.J, Lee, S.J, Yoon, J.Y, Yoon, H.J, Lee, H.Y, Park, S.B, Kim, S.-J, Lee, J.Y, Suh, S.W. 登録日 2009-11-24 公開日 2010-01-19 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (2.73 Å) 主引用文献 Crystal structure of Tpa1 from Saccharomyces cerevisiae, a component of the messenger ribonucleoprotein complex Nucleic Acids Res., 38, 2010
3KTG	Structure of ClpP from Bacillus subtilis in monoclinic crystal form 分子名称: ATP-dependent Clp protease proteolytic subunit 著者 Lee, B.-G, Brotz-Oesterhelt, H, Song, H.K. 登録日 2009-11-25 公開日 2010-03-23 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism Nat.Struct.Mol.Biol., 17, 2010
3KY8	Crystal structure of Putative riboflavin biosynthesis protein (YP_001092907.1) from SHEWANELLA SP. PV-4 at 2.12 A resolution 分子名称: GLYCEROL, Putative riboflavin biosynthesis protein, SULFATE ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2009-12-04 公開日 2009-12-22 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Crystal structure of Putative riboflavin biosynthesis protein (YP_001092907.1) from SHEWANELLA SP. PV-4 at 2.12 A resolution To be published
3KYH	Saccharomyces cerevisiae Cet1-Ceg1 capping apparatus 分子名称: mRNA-capping enzyme subunit alpha, mRNA-capping enzyme subunit beta 著者 Lima, C.D. 登録日 2009-12-06 公開日 2010-02-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of the Saccharomyces cerevisiae Cet1-Ceg1 mRNA Capping Apparatus. Structure, 18, 2010
3KZN	Crystal structure of N-acetyl-L-ornithine transcarbamylase complexed with N-acetyl-L-ornirthine 分子名称: GLYCEROL, N-acetylornithine carbamoyltransferase, N~2~-ACETYL-L-ORNITHINE, ... 著者 Shi, D, Yu, X, Allewell, N.M, Tuchman, M. 登録日 2009-12-08 公開日 2010-03-31 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of N-acetylornithine transcarbamoylase from Xanthomonas campestris complexed with substrates and substrate analogs imply mechanisms for substrate binding and catalysis. Proteins, 64, 2006

<549550551552553554555556557558559560561562563564>