3KPM

Crystal Structure of HLA B*4402 in complex with EEYLKAWTF, a mimotope

Summary for 3KPM

Related3KPL 3KPN 3KPO 3KPP 3KPQ 3KPR 3KPS
DescriptorHLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ... (4 entities in total)
Functional Keywordshla b*4402, allorecognition, tcr recognition, mimotope peptide, disulfide bond, glycoprotein, host-virus interaction, immune response, membrane, mhc i, transmembrane, immune system
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type I membrane protein P30481
Secreted . Note=(Microbial infection) In the presence of M P61769
Total number of polymer chains3
Total molecular weight44915.74
Authors
Primary citation
Macdonald, W.A.,Chen, Z.,Gras, S.,Archbold, J.K.,Tynan, F.E.,Clements, C.S.,Bharadwaj, M.,Kjer-Nielsen, L.,Saunders, P.M.,Wilce, M.C.,Crawford, F.,Stadinsky, B.,Jackson, D.,Brooks, A.G.,Purcell, A.W.,Kappler, J.W.,Burrows, S.R.,Rossjohn, J.,McCluskey, J.
T cell allorecognition via molecular mimicry.
Immunity, 31:897-908, 2009
PubMed: 20064448 (PDB entries with the same primary citation)
DOI: 10.1016/j.immuni.2009.09.025
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.6 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.196401.8%3.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3kpm
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Molmil generated image of 3kpm
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Molmil generated image of 3kpm
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