8YLZ
| Structure of a cis-Geranylfarnesyl Diphosphate Synthase from Streptomyces clavuligerus | 分子名称: | Isoprenyl transferase | 著者 | Li, F.R, Wang, Q.L, Pan, X.M, Dong, L.B. | 登録日 | 2024-03-07 | 公開日 | 2024-05-08 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Discovery, Structure, and Engineering of a cis-Geranylfarnesyl Diphosphate Synthase. Angew.Chem.Int.Ed.Engl., 63, 2024
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5MBW
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5MCO
| CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH ACTIVE SITE INHIBITOR GRL-8234 AND EXOSITE PEPTIDE | 分子名称: | BACE-1 EXOSITE PEPTIDE, Beta-secretase 1, N-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide | 著者 | Kuglstatter, A, Stihle, M, Benz, J. | 登録日 | 2016-11-10 | 公開日 | 2017-09-27 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Potent and Selective BACE-1 Peptide Inhibitors Lower Brain A beta Levels Mediated by Brain Shuttle Transport. EBioMedicine, 24, 2017
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6O1D
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7MJR
| Vip4Da2 toxin structure | 分子名称: | CALCIUM ION, SULFATE ION, Vip4Da1 protein | 著者 | Rydel, T.J, Duda, D, Zheng, M, Henry, A. | 登録日 | 2021-04-20 | 公開日 | 2021-05-05 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | Structural and functional insights into the first Bacillus thuringiensis vegetative insecticidal protein of the Vpb4 fold, active against western corn rootworm. Plos One, 16, 2021
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8T3X
| TNA polymerase, closed ternary | 分子名称: | 10-92, TNA polymerase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Maola, V, Chaput, J, Chim, N. | 登録日 | 2023-06-07 | 公開日 | 2024-08-28 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Directed Evolution of a Highly Efficient TNA Polymerase Achieved by Homologous Recombination To Be Published
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7TVH
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7MFU
| Crystal structure of synthetic nanobody (Sb14+Sb68) complexes with SARS-CoV-2 receptor binding domain | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Spike protein S1, ... | 著者 | Jiang, J, Ahmad, J, Natarajan, K, Boyd, L.F, Margulies, D.H. | 登録日 | 2021-04-11 | 公開日 | 2021-06-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction. J.Biol.Chem., 297, 2021
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7MFV
| Crystal structure of synthetic nanobody (Sb16) | 分子名称: | 1,2-ETHANEDIOL, Synthetic Nanobody #16 (Sb16) | 著者 | Jiang, J, Ahmad, J, Natarajan, K, Boyd, L.F, Margulies, D.H. | 登録日 | 2021-04-11 | 公開日 | 2021-06-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction. J.Biol.Chem., 297, 2021
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7MKQ
| Escherichia coli RNA polymerase and RapA binary complex | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Qayyum, M.Z, Murakami, K.S. | 登録日 | 2021-04-26 | 公開日 | 2021-06-02 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Structural basis of RNA polymerase recycling by the Swi2/Snf2 family of ATPase RapA in Escherichia coli. J.Biol.Chem., 297, 2021
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7TRG
| The beta-tubulin folding intermediate I | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | 著者 | Zhao, Y, Frydman, J, Chiu, W. | 登録日 | 2022-01-28 | 公開日 | 2022-12-28 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
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7TSX
| Structure of Enterobacter cloacae Cap2 bound to CdnD02 C-terminus, Apo state | 分子名称: | Cap2, Cyclic AMP-AMP-GMP synthase | 著者 | Ye, Q, Gu, Y, Ledvina, H.E, Quan, Y, Lau, R.K, Zhou, H, Whiteley, A.T, Corbett, K.D. | 登録日 | 2022-01-31 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | An E1-E2 fusion protein primes antiviral immune signalling in bacteria. Nature, 616, 2023
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7WR4
| Crystal structure of OspC3-calmodulin-caspase-4 complex | 分子名称: | Calmodulin-1, Caspase-4, OspC3 | 著者 | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | 登録日 | 2022-01-26 | 公開日 | 2023-01-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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7TSQ
| Structure of Enterobacter cloacae Cap2 bound to CdnD02 C-terminus, AMP state | 分子名称: | ADENOSINE MONOPHOSPHATE, Cap2, Cyclic AMP-AMP-GMP synthase, ... | 著者 | Ye, Q, Gu, Y, Ledvina, H.E, Quan, Y, Lau, R.K, Zhou, H, Whiteley, A.T, Corbett, K.D. | 登録日 | 2022-01-31 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | An E1-E2 fusion protein primes antiviral immune signalling in bacteria. Nature, 616, 2023
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5MB5
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7WR2
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7WR0
| P32 of caspase-4 C258A mutant | 分子名称: | Caspase-4 | 著者 | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | 登録日 | 2022-01-26 | 公開日 | 2023-01-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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7TNC
| M13F/G116F Pseudomonas aeruginosa azurin | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Azurin, CHLORIDE ION, ... | 著者 | Liu, Y, Lu, Y. | 登録日 | 2022-01-20 | 公開日 | 2023-01-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Structural Basis for the Effects of Phenylalanine on Tuning the Reduction Potential of Type 1 Copper in Azurin. Inorg.Chem., 62, 2023
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7WKO
| ICP1 Csy1-2 complex | 分子名称: | Csy1, Csy2 | 著者 | Zhang, M, Peng, R. | 登録日 | 2022-01-10 | 公開日 | 2023-04-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage. Proc.Natl.Acad.Sci.USA, 120, 2023
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7TXY
| Crystal structure of the 2-Aminophenol 1,6-dioxygenase from the ARO bacterial microcompartment of Micromonospora rosaria | 分子名称: | 2-amino-5-chlorophenol 1,6-dioxygenase subunit alpha, 2-aminophenol 1,6-dioxygenase subunit beta, FE (II) ION | 著者 | Sutter, M, Doron, L, Kerfeld, C.A. | 登録日 | 2022-02-10 | 公開日 | 2023-02-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Characterization of a novel aromatic substrate-processing microcompartment in Actinobacteria. Mbio, 14, 2023
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8TUI
| Crystal structure of Fab-Lirilumab bound to KIR2DL3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Killer cell immunoglobulin-like receptor 2DL3, Lirilumab Fab Heavy Chain, ... | 著者 | Lorig-Roach, N, DuBois, R.M. | 登録日 | 2023-08-16 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural basis for the activity and specificity of the immune checkpoint inhibitor lirilumab. Sci Rep, 14, 2024
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8U0P
| Synaptic complex of human DNA polymerase Lambda DL variant engaged on a noncomplementary DNA double-strand break | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ... | 著者 | Kaminski, A.M, Pedersen, L.C, Bebenek, K, Kunkel, T.A, Chiruvella, K.K, Ramsden, D.A. | 登録日 | 2023-08-29 | 公開日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | DNA polymerase lambda Loop1 variant yields unexpected gain-of-function capabilities in nonhomologous end-joining. DNA Repair (Amst), 136, 2024
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8U8M
| X-ray crystal structure of TEBP-1 MCD2 homodimer | 分子名称: | COBALT (II) ION, Double-strand telomeric DNA-binding proteins 1 | 著者 | Nandakumar, J, Padmanaban, S. | 登録日 | 2023-09-18 | 公開日 | 2024-04-03 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Caenorhabditis elegans telomere-binding proteins TEBP-1 and TEBP-2 adapt the Myb module to dimerize and bind telomeric DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
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8U8L
| X-ray crystal structure of TEBP-2 MCD3 with ds DNA | 分子名称: | CESIUM ION, DNA (5'-D(*CP*TP*GP*TP*TP*AP*GP*GP*CP*TP*TP*AP*GP*GP*CP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*GP*CP*CP*TP*AP*AP*GP*CP*CP*TP*AP*AP*CP*A)-3'), ... | 著者 | Nandakumar, J, Padmanaban, S. | 登録日 | 2023-09-18 | 公開日 | 2024-04-03 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Caenorhabditis elegans telomere-binding proteins TEBP-1 and TEBP-2 adapt the Myb module to dimerize and bind telomeric DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
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7M75
| Room Temperature XFEL Crystallography reveals asymmetry in the vicinity of the two phylloquinones in Photosystem I | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | 著者 | Keable, S.M, Simon, P.S, Kolsch, A, Kern, J, Yachandra, V.K, Zouni, A, Yano, J. | 登録日 | 2021-03-26 | 公開日 | 2021-11-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Room temperature XFEL crystallography reveals asymmetry in the vicinity of the two phylloquinones in photosystem I. Sci Rep, 11, 2021
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