PDB: 72236 件ウェブページステータス検索Chemie searchBIRD

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8EKB	Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, deacylated P-site tRNAmet, and thermorubin at 2.70A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Paranjpe, M.N, Polikanov, Y.S. 登録日 2022-09-20 公開日 2022-12-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin. Nucleic Acids Res., 51, 2023
4B7C	Crystal structure of hypothetical protein PA1648 from Pseudomonas aeruginosa. 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PROBABLE OXIDOREDUCTASE 著者 Alphey, M.S, McMahon, S.A, Duthie, F.G, Naismith, J.H. 登録日 2012-08-17 公開日 2013-01-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery Acta Crystallogr.,Sect.F, 69, 2013
8BIT	Crystal structure of acyl-CoA synthetase from Metallosphaera sedula in complex with Coenzyme A and acetyl-AMP 分子名称: 4-hydroxybutyrate--CoA ligase 1, COENZYME A, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] ethanoate 著者 Capra, N, Thunnissen, A.M.W.H, Janssen, D.B. 登録日 2022-11-02 公開日 2023-11-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Adapting an acyl CoA ligase from Metallosphaera sedula for lactam formation by structure-guided protein engineering Front Catal, 4, 2024
4AXC	Inositol 1,3,4,5,6-pentakisphosphate 2-kinase apo form 分子名称: GLYCEROL, INOSITOL-PENTAKISPHOSPHATE 2-KINASE, SULFATE ION, ... 著者 I Banos-Sanz, J, Sanz-Aparicio, J, Gonzalez, B. 登録日 2012-06-12 公開日 2012-07-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Conformational Changes Undergone by Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase Upon Substrate Binding: The Role of N-Lobe and Enantiomeric Substrate Preference J.Biol.Chem., 287, 2012
4OZI	S2 protein complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HLA class II histocompatibility antigen, ... 著者 Petersen, J, Reid, H.H, Rossjohn, J. 登録日 2014-02-16 公開日 2014-04-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease. Nat.Struct.Mol.Biol., 21, 2014
4AXQ	CRYSTAL STRUCTURE OF ARCHAEMETZINCIN (AMZA) FROM ARCHAEOGLOBUS FULGIDUS AT 1.4 A RESOLUTION 分子名称: ARCHAEMETZINCIN, ZINC ION 著者 Graef, C, Schacherl, M, Baumann, U. 登録日 2012-06-13 公開日 2012-06-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal Structures of Archaemetzincin Reveal a Moldable Substrate-Binding Site. Plos One, 7, 2012
4AXE	Inositol 1,3,4,5,6-pentakisphosphate 2-kinase in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, INOSITOL-PENTAKISPHOSPHATE 2-KINASE, SULFATE ION, ... 著者 I Banos-Sanz, J, Sanz-Aparicio, J, Gonzalez, B. 登録日 2012-06-12 公開日 2012-07-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Conformational Changes Undergone by Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase Upon Substrate Binding: The Role of N-Lobe and Enantiomeric Substrate Preference J.Biol.Chem., 287, 2012
8BT3	Ribonucleotide Reductase class Ie R2 from Mesoplasma florum, catalytically active radical state solved by XFEL 分子名称: Ribonucleoside-diphosphate reductase beta chain 著者 Lebrette, H, Srinivas, V, Hogbom, M. 登録日 2022-11-27 公開日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of a ribonucleotide reductase R2 protein radical. Science, 382, 2023
8BIQ	Crystal structure of acyl-COA synthetase from Metallosphaera sedula in complex with acetyl-AMP 分子名称: 4-hydroxybutyrate--CoA ligase 1, ADENOSINE MONOPHOSPHATE, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] ethanoate 著者 Capra, N, Thunnissen, A.M.W.H, Janssen, D.B. 登録日 2022-11-02 公開日 2023-11-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Adapting an acyl CoA ligase from Metallosphaera sedula for lactam formation by structure-guided protein engineering Front Catal, 4, 2024
4OKA	Structural-, Kinetic- and Docking Studies of Artificial Imine Reductases Based on the Biotin-Streptavidin Technology: An Induced Lock-and-Key Hypothesis 分子名称: IRIDIUM ION, Streptavidin, [N-(4-{[2-(amino-kappaN)ethyl]sulfamoyl-kappaN}phenyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamidato]iridium(III) 著者 Schirmer, T, Heinisch, T. 登録日 2014-01-22 公開日 2014-11-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.505 Å) 主引用文献 Structural, Kinetic, and Docking Studies of Artificial Imine Reductases Based on Biotin-Streptavidin Technology: An Induced Lock-and-Key Hypothesis J.Am.Chem.Soc., 136, 2014
4BTB	CRYSTAL STRUCTURE OF THE PEPTIDE(PRO)9 BOUND COMPLEX OF N-TERMINAL DOMAIN AND PEPTIDE SUBSTRATE BINDING DOMAIN OF PROLYL-4 HYDROXYLASE (RESIDUES 1-238) TYPE I FROM HUMAN 分子名称: POLY PROLINE PEPTIDE, PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-1 著者 Anantharajan, J, Koski, M.K, Wierenga, R.K. 登録日 2013-06-14 公開日 2013-10-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.899 Å) 主引用文献 The Structural Motifs for Substrate Binding and Dimerization of the Alpha Subunit of Collagen Prolyl 4-Hydroxylase Structure, 21, 2013
4OVH	E. coli sliding clamp in complex with (R)-6-bromo-9-(2-(carboxymethylamino)-2-oxoethyl)-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid 分子名称: (2R)-6-bromo-9-{2-[(carboxymethyl)amino]-2-oxoethyl}-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... 著者 Yin, Z, Oakley, A.J. 登録日 2014-02-21 公開日 2014-03-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J.Med.Chem., 58, 2015
4OQB	Structure of Human PARP-1 bound to a DNA double strand break in complex with (2Z)-2-{4-[2-(morpholin-4-yl)ethoxy]benzylidene}-3-oxo-2,3-dihydro-1-benzofuran-7-carboxamide 分子名称: (2Z)-2-{4-[2-(morpholin-4-yl)ethoxy]benzylidene}-3-oxo-2,3-dihydro-1-benzofuran-7-carboxamide, DNA (26-MER), Poly [ADP-ribose] polymerase 1, ... 著者 Pascal, J.M, Steffen, J.D. 登録日 2014-02-07 公開日 2014-07-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.362 Å) 主引用文献 Discovery and Structure-Activity Relationship of Novel 2,3-Dihydrobenzofuran-7-carboxamide and 2,3-Dihydrobenzofuran-3(2H)-one-7-carboxamide Derivatives as Poly(ADP-ribose)polymerase-1 Inhibitors. J.Med.Chem., 57, 2014
1EBY	HIV-1 protease in complex with the inhibitor BEA369 分子名称: HIV-1 PROTEASE, N,N-[2,5-O-DIBENZYL-GLUCARYL]-DI-[1-AMINO-INDAN-2-OL] 著者 Unge, T. 登録日 2000-01-25 公開日 2002-06-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.294 Å) 主引用文献 Optimization of P1-P3 groups in symmetric and asymmetric HIV-1 protease inhibitors Eur.J.Biochem., 270, 2003
8BW9	Cryo-EM structure of the RAF activating complex KSR-MEK-CNK-HYP 分子名称: Connector enhancer of KSR protein CNK, Dual specificity mitogen-activated protein kinase kinase dSOR1, KSR, ... 著者 Maisonneuve, P, Fronzes, R, Sicheri, F. 登録日 2022-12-06 公開日 2024-02-21 最終更新日 2024-07-31 実験手法 ELECTRON MICROSCOPY (3.32 Å) 主引用文献 The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction. Nat.Struct.Mol.Biol., 31, 2024
8BW8	Crystal structure of the dCNK-SAM-CRIC-PDZ/dHYP-SAM complex 分子名称: Connector enhancer of KSR protein CNK, GLYCEROL, Protein aveugle 著者 Maisonneuve, P, Kurinov, I, Sicheri, F. 登録日 2022-12-06 公開日 2024-02-21 最終更新日 2024-07-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction. Nat.Struct.Mol.Biol., 31, 2024
4OHO	Human GKRP bound to AMG-2668 分子名称: 5-{[(3S)-3-(prop-1-yn-1-yl)-4-{4-[S-(trifluoromethyl)sulfonimidoyl]phenyl}piperazin-1-yl]sulfonyl}pyridin-2-amine, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ... 著者 Jordan, S.R, Chmait, S. 登録日 2014-01-17 公開日 2014-07-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 3. Structure-activity relationships within the aryl carbinol region of the N-arylsulfonamido-N'-arylpiperazine series. J.Med.Chem., 57, 2014
4OZG	D2 protein complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Petersen, J, Reid, H.H, Rossjohn, J. 登録日 2014-02-16 公開日 2014-04-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease. Nat.Struct.Mol.Biol., 21, 2014
4DMF	Crystal structure of the CFTR inhibitory factor Cif with the H177A mutation 分子名称: Putative hydrolase 著者 Bahl, C.D, Madden, D.R. 登録日 2012-02-07 公開日 2013-08-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Inhibiting an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Protects CFTR. Angew.Chem.Int.Ed.Engl., 54, 2015
4DMK	Crystal structure of the CFTR inhibitory factor Cif with the Y239F mutation 分子名称: GLYCEROL, Putative hydrolase 著者 Bahl, C.D, Madden, D.R. 登録日 2012-02-07 公開日 2013-08-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Inhibiting an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Protects CFTR. Angew.Chem.Int.Ed.Engl., 54, 2015
2MJS	Anoplin R5K T8W in DPC micelles 分子名称: Anoplin, UNKNOWN ATOM OR ION, dodecyl 2-(trimethylammonio)ethyl phosphate 著者 Uggerhoej, L, Poulsen, T.J, Wimmer, R. 登録日 2014-01-16 公開日 2014-12-03 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Rational Design of Alpha-Helical Antimicrobial Peptides: Do's and Don'ts. Chembiochem, 16, 2015
4BGA	Nucleotide-bound open form of a putative sugar kinase MK0840 from Methanopyrus kandleri 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, POTASSIUM ION, ... 著者 Schacherl, M, Baumann, U. 登録日 2013-03-24 公開日 2013-11-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Characterization of the Ribonuclease H-Like Type Askha Superfamily Kinase Mk0840 from Methanopyrus Kandleri Acta Crystallogr.,Sect.D, 69, 2013
4BIP	Homology model of coxsackievirus A7 (CAV7) full capsid proteins. 分子名称: VP1, VP2, VP3 著者 Seitsonen, J.J.T, Shakeel, S, Susi, P, Pandurangan, A.P, Sinkovits, R.S, Hyvonen, H, Laurinmaki, P, Yla-Pelto, J, Topf, M, Hyypia, T, Butcher, S.J. 登録日 2013-04-12 公開日 2013-10-02 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (8.23 Å) 主引用文献 Combined Approaches to Flexible Fitting and Assessment in Virus Capsids Undergoing Conformational Change. J.Struct.Biol., 185, 2014
2MJK	Nmr structure of hen egg beta-defensin gallin (chicken ovo-defensin) 分子名称: Gallin protein 著者 Landon, C, Meudal, H. 登録日 2014-01-10 公開日 2014-01-22 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Three-dimensional NMR Structure of Hen Egg Gallin (Chicken Ovodefensin) Reveals a New Variation of the beta-Defensin Fold. J.Biol.Chem., 289, 2014
4PNW	E. coli sliding clamp in complex with (R)-6-bromo-9-(2-((S)-1-carboxy-2-phenylethylamino)-2-oxoethyl)-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid 分子名称: (2R)-6-bromo-9-(2-{[(1S)-1-carboxy-2-phenylethyl]amino}-2-oxoethyl)-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... 著者 Yin, Z, Oakley, A.J. 登録日 2014-02-21 公開日 2014-03-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J.Med.Chem., 58, 2015

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