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4ARZ
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BU of 4arz by Molmil
The crystal structure of Gtr1p-Gtr2p complexed with GTP-GDP
分子名称: GTP-BINDING PROTEIN GTR1, GTP-BINDING PROTEIN GTR2, GUANOSINE-5'-DIPHOSPHATE, ...
著者Jeong, J.H, Kim, Y.G.
登録日2012-04-27
公開日2012-07-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of the Gtr1Pgtp-Gtr2Pgdp Complex Reveals Large Structural Rearrangements Triggered by GTP-to-Gdp Conversion
J.Biol.Chem., 287, 2012
7ZMU
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BU of 7zmu by Molmil
14-3-3s binding to non-natural peptide 2d
分子名称: 14-3-3 protein sigma, MAGNESIUM ION, non-natural peptide 2
著者Somsen, B.A, Craenmehr, F.W.B, Ottmann, C.
登録日2022-04-19
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Functional mapping of the 14-3-3 hub protein as a guide to design 14-3-3 molecular glues.
Chem Sci, 13, 2022
4WSZ
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BU of 4wsz by Molmil
Crystal structure of the DNA binding domains of wild type LiaR from E. faecalis
分子名称: ACETATE ION, GLYCEROL, PRASEODYMIUM ION, ...
著者Davlieva, M, Shamoo, Y.
登録日2014-10-29
公開日2015-05-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.769 Å)
主引用文献A variable DNA recognition site organization establishes the LiaR-mediated cell envelope stress response of enterococci to daptomycin.
Nucleic Acids Res., 43, 2015
4WT0
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BU of 4wt0 by Molmil
Crystal structure of the DNA binding domains of LiaRD191N from E. faecalis
分子名称: PRASEODYMIUM ION, Response regulator receiver domain protein
著者Davlieva, M, Shamoo, Y.
登録日2014-10-29
公開日2015-05-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A variable DNA recognition site organization establishes the LiaR-mediated cell envelope stress response of enterococci to daptomycin.
Nucleic Acids Res., 43, 2015
7AOG
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BU of 7aog by Molmil
14-3-3 sigma in complex with Pin1 binding site pS72
分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ...
著者Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C.
登録日2020-10-14
公開日2021-06-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions.
J.Am.Chem.Soc., 143, 2021
6VCD
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BU of 6vcd by Molmil
Cryo-EM structure of IRP2-FBXL5-SKP1 complex
分子名称: F-box/LRR-repeat protein 5, FE2/S2 (INORGANIC) CLUSTER, Iron-responsive element binding protein 2, ...
著者Wang, H, Shi, H, Zheng, N.
登録日2019-12-20
公開日2020-08-05
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster.
Mol.Cell, 78, 2020
6POR
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BU of 6por by Molmil
Antimicrobial lasso peptide ubonodin
分子名称: Ubonodin
著者Link, A.J, Cheung-Lee, W.L.
登録日2019-07-05
公開日2019-12-04
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Discovery of Ubonodin, an Antimicrobial Lasso Peptide Active against Members of the Burkholderia cepacia Complex.
Chembiochem, 21, 2020
8K6Z
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BU of 8k6z by Molmil
NMR structure of human leptin
分子名称: Leptin
著者Fan, X, Qin, R, Yuan, W, Fan, J, Huang, W, Lin, Z.
登録日2023-07-26
公開日2024-02-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The solution structure of human leptin reveals a conformational plasticity important for receptor recognition.
Structure, 32, 2024
7BG3
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BU of 7bg3 by Molmil
14-3-3 sigma with Pin1 binding site pS72 and covalently bound PC2046
分子名称: 1-(3-bromanyl-4-methyl-phenyl)-2-(2-bromophenyl)imidazole, 14-3-3 protein sigma, CALCIUM ION, ...
著者Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C.
登録日2021-01-05
公開日2021-06-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions.
J.Am.Chem.Soc., 143, 2021
5XQM
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BU of 5xqm by Molmil
NMR solution structure of SMO1, Sumo homologue in Caenorhabditis elegans
分子名称: Small ubiquitin-related modifier
著者Gowda, C.M, Surana, P, Das, R.
登録日2017-06-07
公開日2017-11-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural and functional analysis of SMO-1, the SUMO homolog in Caenorhabditis elegans
PLoS ONE, 12, 2017
1C20
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BU of 1c20 by Molmil
SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN FROM THE DEAD RINGER PROTEIN
分子名称: DEAD RINGER PROTEIN
著者Iwahara, J, Clubb, R.T.
登録日1999-07-22
公開日1999-11-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the DNA binding domain from Dead ringer, a sequence-specific AT-rich interaction domain (ARID).
EMBO J., 18, 1999
8FP5
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BU of 8fp5 by Molmil
CDK2 liganded with ATP and Mg2+
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Cyclin-dependent kinase 2, ...
著者Schonbrunn, E, Sun, L.
登録日2023-01-04
公開日2023-05-31
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding.
Nat Commun, 14, 2023
1B4T
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BU of 1b4t by Molmil
H48C YEAST CU(II)/ZN SUPEROXIDE DISMUTASE ROOM TEMPERATURE (298K) STRUCTURE
分子名称: CHLORIDE ION, COPPER (II) ION, PROTEIN (CU/ZN SUPEROXIDE DISMUTASE), ...
著者Hart, P.J, Balbirnie, M.M, Ogihara, N.L, Nersissian, A.M, Weiss, M.S, Valentine, J.S, Eisenberg, D.
登録日1998-12-23
公開日1999-12-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A structure-based mechanism for copper-zinc superoxide dismutase.
Biochemistry, 38, 1999
1B4L
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BU of 1b4l by Molmil
15 ATMOSPHERE OXYGEN YEAST CU/ZN SUPEROXIDE DISMUTASE ROOM TEMPERATURE (298K) STRUCTURE
分子名称: COPPER (II) ION, PROTEIN (CU/ZN SUPEROXIDE DISMUTASE), ZINC ION
著者Hart, P.J, Balbirnie, M.M, Ogihara, N.L, Nersissian, A.M, Weiss, M.S, Valentine, J.S, Eisenberg, D.
登録日1998-12-22
公開日1999-12-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A structure-based mechanism for copper-zinc superoxide dismutase.
Biochemistry, 38, 1999
1YFD
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BU of 1yfd by Molmil
Crystal structure of the Y122H mutant of ribonucleotide reductase R2 protein from E. coli
分子名称: MERCURY (II) ION, MU-OXO-DIIRON, Ribonucleoside-diphosphate reductase 1 beta chain
著者Kolberg, M, Logan, D.T, Bleifuss, G, Poetsch, S, Sjoeberg, B.M, Graeslund, A, Lubitz, W, Lassmann, G, Lendzian, F.
登録日2004-12-31
公開日2005-02-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A new tyrosyl radical on Phe208 as ligand to the diiron center in Escherichia coli ribonucleotide reductase, mutant R2-Y122H. Combined x-ray diffraction and EPR/ENDOR studies
J.Biol.Chem., 280, 2005
7RWF
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BU of 7rwf by Molmil
Crystal structure of CDK2 in complex with TW8672
分子名称: 1,2-ETHANEDIOL, 2-{[2-(1H-indol-3-yl)ethyl]amino}-5-nitrobenzoic acid, Cyclin-dependent kinase 2
著者Sun, L, Schonbrunn, E.
登録日2021-08-19
公開日2022-08-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding.
Nat Commun, 14, 2023
7S84
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BU of 7s84 by Molmil
Crystal structure of CDK2 liganded with compound TW8972
分子名称: 2-{[2-(1H-indol-3-yl)ethyl]amino}-5-(trifluoromethyl)benzoic acid, Cyclin-dependent kinase 2
著者Sun, L, Schonbrunn, E.
登録日2021-09-17
公開日2022-09-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding.
Nat Commun, 14, 2023
4MHG
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BU of 4mhg by Molmil
Crystal structure of ETV6 bound to a specific DNA sequence
分子名称: Complementary Specific 14 bp DNA, Specific 14 bp DNA, Transcription factor ETV6
著者Chan, A.C, De, S, Coyne III, H.J, Okon, M, Murphy, M.E, Graves, B.J, McIntosh, L.P.
登録日2013-08-29
公開日2014-01-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6.
J.Mol.Biol., 426, 2014
2LSV
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BU of 2lsv by Molmil
The NMR high resolution structure of yeast Tah1 in complex with the Hsp90 C-terminal tail
分子名称: ATP-dependent molecular chaperone HSP82, TPR repeat-containing protein associated with Hsp90
著者Back, R, Dominguez, C, Rothe, B, Bobo, C, Beaufils, C, Morera, S, Meyer, P, Charpentier, B, Branlant, C, Allain, F, Manival, X.
登録日2012-05-07
公開日2013-05-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献High-Resolution Structural Analysis Shows How Tah1 Tethers Hsp90 to the R2TP Complex.
Structure, 21, 2013
6ZV1
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BU of 6zv1 by Molmil
TFIIS N-terminal domain (TND) from human IWS1
分子名称: Protein IWS1 homolog
著者Veverka, V.
登録日2020-07-23
公開日2021-12-01
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献A ubiquitous disordered protein interaction module orchestrates transcription elongation.
Science, 374, 2021
6ZV2
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BU of 6zv2 by Molmil
TFIIS N-terminal domain (TND) from human PPP1R10
分子名称: Serine/threonine-protein phosphatase 1 regulatory subunit 10
著者Veverka, V.
登録日2020-07-23
公開日2021-12-01
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献A ubiquitous disordered protein interaction module orchestrates transcription elongation.
Science, 374, 2021
6ZV4
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BU of 6zv4 by Molmil
Human TFIIS N-terminal domain in complex with IWS1
分子名称: Transcription elongation factor A protein 1,Protein IWS1 homolog
著者Veverka, V.
登録日2020-07-23
公開日2021-12-01
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献A ubiquitous disordered protein interaction module orchestrates transcription elongation.
Science, 374, 2021
6ZV0
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BU of 6zv0 by Molmil
TFIIS N-terminal domain (TND) from human LEDGF/p75
分子名称: PC4 and SFRS1-interacting protein
著者Veverka, V.
登録日2020-07-23
公開日2021-12-01
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献A ubiquitous disordered protein interaction module orchestrates transcription elongation.
Science, 374, 2021
6E8E
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BU of 6e8e by Molmil
Crystal structure of the Escherichia coli sliding clamp-MutL complex.
分子名称: Beta sliding clamp,DNA mismatch repair protein MutL, GLYCEROL, SULFATE ION
著者Guarne, A, Almawi, A.W.
登録日2018-07-28
公開日2019-05-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Binding of the regulatory domain of MutL to the sliding beta-clamp is species specific.
Nucleic Acids Res., 47, 2019
3QWR
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BU of 3qwr by Molmil
Crystal structure of IL-23 in complex with an adnectin
分子名称: ADNECTIN, Interleukin-12 subunit beta, Interleukin-23 subunit alpha, ...
著者Wei, A, Sheriff, S.
登録日2011-02-28
公開日2012-02-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structures of adnectin/protein complexes reveal an expanded binding footprint.
Structure, 20, 2012

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