1Q9X
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![BU of 1q9x by Molmil](/molmil-images/mine/1q9x) | Crystal structure of Enterobacteria phage RB69 gp43 DNA polymerase complexed with tetrahydrofuran containing DNA | 分子名称: | 1',2'-DIDEOXYRIBOFURANOSE-5'-PHOSPHATE, 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ... | 著者 | Freisinger, E, Grollman, A.P, Miller, H, Kisker, C. | 登録日 | 2003-08-26 | 公開日 | 2004-04-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Lesion (in)tolerance reveals insights into DNA replication fidelity. Embo J., 23, 2004
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1LFG
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![BU of 1lfg by Molmil](/molmil-images/mine/1lfg) | Structure of diferric human lactoferrin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | 著者 | Baker, E.N, Anderson, B.F, Haridas, M. | 登録日 | 1992-02-05 | 公開日 | 1994-01-31 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of human diferric lactoferrin refined at 2.2 A resolution. Acta Crystallogr.,Sect.D, 51, 1995
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4ZQC
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![BU of 4zqc by Molmil](/molmil-images/mine/4zqc) | Tryptophan Synthase from Salmonella typhimurium in complex with two molecules of N-(4'-trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (F6F) inhibitor in the alpha-site and a single F6F molecule in the beta-site at 1.54 Angstrom resolution. | 分子名称: | 2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL DIHYDROGEN PHOSPHATE, DIMETHYL SULFOXIDE, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Hilario, E, Caulkins, B.G, Young, R.P, Dunn, M.F, Mueller, L.J, Fan, L. | 登録日 | 2015-05-08 | 公開日 | 2016-02-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Visualizing the tunnel in tryptophan synthase with crystallography: Insights into a selective filter for accommodating indole and rejecting water. Biochim.Biophys.Acta, 1864, 2016
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6H65
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![BU of 6h65 by Molmil](/molmil-images/mine/6h65) | Crystal structure of the branched-chain-amino-acid aminotransferase from Haliangium ochraceum | 分子名称: | Branched-chain-amino-acid aminotransferase, PYRIDOXAL-5'-PHOSPHATE | 著者 | Boyko, K.M, Timofeev, V.I, Bezsudnova, E.Y, Nikolaeva, A.Y, Rakitina, T.V, Popov, V.O. | 登録日 | 2018-07-26 | 公開日 | 2018-10-10 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal structure of the branched-chain-amino-acid aminotransferase from Haliangium ochraceum To Be Published
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4Z7I
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![BU of 4z7i by Molmil](/molmil-images/mine/4z7i) | Crystal structure of insulin regulated aminopeptidase in complex with ligand | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DG025 transition-state analogue enzyme inhibitor, ... | 著者 | Mpakali, A, Saridakis, E, Harlos, K, Zhao, Y, Stratikos, E. | 登録日 | 2015-04-07 | 公開日 | 2015-08-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | 主引用文献 | Crystal Structure of Insulin-Regulated Aminopeptidase with Bound Substrate Analogue Provides Insight on Antigenic Epitope Precursor Recognition and Processing. J Immunol., 195, 2015
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4ZF6
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![BU of 4zf6 by Molmil](/molmil-images/mine/4zf6) | Cytochrome P450 pentamutant from BM3 with bound PEG | 分子名称: | 1,2-ETHANEDIOL, Bifunctional P-450/NADPH-P450 reductase, NICKEL (II) ION, ... | 著者 | Rogers, W.E, Othman, T, Heidary, D.K, Huxford, T. | 登録日 | 2015-04-21 | 公開日 | 2016-07-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.773 Å) | 主引用文献 | Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants. Biochemistry, 55, 2016
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7JMT
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![BU of 7jmt by Molmil](/molmil-images/mine/7jmt) | Crystal structure of schistosome BCL-2 bound to ABT-737 | 分子名称: | 4-{4-[(4'-CHLOROBIPHENYL-2-YL)METHYL]PIPERAZIN-1-YL}-N-{[4-({(1R)-3-(DIMETHYLAMINO)-1-[(PHENYLTHIO)METHYL]PROPYL}AMINO)-3-NITROPHENYL]SULFONYL}BENZAMIDE, BCL-2 protein | 著者 | Smith, N.A, Smith, B.J, Lee, E.F, Colman, P.M, Fairlie, W.D. | 登録日 | 2020-08-02 | 公開日 | 2021-02-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Optimization of Benzothiazole and Thiazole Hydrazones as Inhibitors of Schistosome BCL-2. Acs Infect Dis., 7, 2021
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1BOF
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![BU of 1bof by Molmil](/molmil-images/mine/1bof) | GI-ALPHA-1 BOUND TO GDP AND MAGNESIUM | 分子名称: | GI ALPHA 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Coleman, D.E, Sprang, S.R. | 登録日 | 1998-08-04 | 公開日 | 1999-01-06 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of the G protein Gi alpha 1 complexed with GDP and Mg2+: a crystallographic titration experiment. Biochemistry, 37, 1998
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7XTB
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![BU of 7xtb by Molmil](/molmil-images/mine/7xtb) | Serotonin 6 (5-HT6) receptor-Gs-Nb35 complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Huang, S, Xu, P, Shen, D.D, Simon, I.A, Mao, C, Tan, Y, Zhang, H, Harpsoe, K, Li, H, Zhang, Y, You, C, Yu, X, Jiang, Y, Zhang, Y, Gloriam, D.E, Xu, H.E. | 登録日 | 2022-05-16 | 公開日 | 2022-07-27 | 最終更新日 | 2022-08-03 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors. Mol.Cell, 82, 2022
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7XTC
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![BU of 7xtc by Molmil](/molmil-images/mine/7xtc) | Serotonin 7 (5-HT7) receptor-Gs-Nb35 complex | 分子名称: | 3-(2-azanylethyl)-1H-indole-5-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Huang, S, Xu, P, Shen, D.D, Simon, I.A, Mao, C, Tan, Y, Zhang, H, Harpsoe, K, Li, H, Zhang, Y, You, C, Yu, X, Jiang, Y, Zhang, Y, Gloriam, D.E, Xu, H.E. | 登録日 | 2022-05-16 | 公開日 | 2022-07-27 | 最終更新日 | 2022-08-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors. Mol.Cell, 82, 2022
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6MZ0
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![BU of 6mz0 by Molmil](/molmil-images/mine/6mz0) | Crystal structure of Tdp1 catalytic domain in complex with compound XZ530 | 分子名称: | 1,2-ETHANEDIOL, 5-hydroxypyrazine-2,3-dicarboxylic acid, Tyrosyl-DNA phosphodiesterase 1 | 著者 | Lountos, G.T, Zhao, X.Z, Kiselev, E, Tropea, J.E, Needle, D, Burke Jr, T.R, Pommier, Y, Waugh, D.S. | 登録日 | 2018-11-02 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.969 Å) | 主引用文献 | Structure of Tdp1 catalytic domain in complex with compound XZ530 To Be Published
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7JW7
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![BU of 7jw7 by Molmil](/molmil-images/mine/7jw7) | Structure of monobody 27 human MLKL pseudokinase domain complex | 分子名称: | Mixed lineage kinase domain-like protein, Monobody 27 | 著者 | Meng, Y, Garnish, S.E, Koide, A, Koide, S, Czabotar, P.E, Murphy, J.M. | 登録日 | 2020-08-25 | 公開日 | 2021-03-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis. Nat Commun, 12, 2021
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7XT9
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![BU of 7xt9 by Molmil](/molmil-images/mine/7xt9) | Serotonin 4 (5-HT4) receptor-Gs complex | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Huang, S, Xu, P, Shen, D.D, Simon, I.A, Mao, C, Tan, Y, Zhang, H, Harpsoe, K, Li, H, Zhang, Y, You, C, Yu, X, Jiang, Y, Zhang, Y, Gloriam, D.E, Xu, H.E. | 登録日 | 2022-05-16 | 公開日 | 2022-07-27 | 最終更新日 | 2022-08-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors. Mol.Cell, 82, 2022
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7XT8
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![BU of 7xt8 by Molmil](/molmil-images/mine/7xt8) | Serotonin 4 (5-HT4) receptor-Gs-Nb35 complex | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Huang, S, Xu, P, Shen, D.D, Simon, I.A, Mao, C, Tan, Y, Zhang, H, Harpsoe, K, Li, H, Zhang, Y, You, C, Yu, X, Jiang, Y, Zhang, Y, Gloriam, D.E, Xu, H.E. | 登録日 | 2022-05-16 | 公開日 | 2022-07-27 | 最終更新日 | 2022-08-03 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors. Mol.Cell, 82, 2022
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6N0R
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![BU of 6n0r by Molmil](/molmil-images/mine/6n0r) | Crystal structure of Tdp1 catalytic domain in complex with compound XZ572 | 分子名称: | 1,2-ETHANEDIOL, 4-(methylamino)benzene-1,2-dicarboxylic acid, DIMETHYL SULFOXIDE, ... | 著者 | Lountos, G.T, Zhao, X.Z, Kiselev, E, Tropea, J.E, Needle, D, Burke Jr, T.R, Pommier, Y, Waugh, D.S. | 登録日 | 2018-11-07 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.544 Å) | 主引用文献 | Crystal structure of Tdp1 catalytic domain To Be Published
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6GXX
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![BU of 6gxx by Molmil](/molmil-images/mine/6gxx) | Fab fragment of an antibody selective for alpha-1-antitrypsin in the native conformation | 分子名称: | FAB 1D9 heavy chain, FAB 1D9 light chain, MAGNESIUM ION | 著者 | Elliston, E.L.K, Miranda, E, Perez, J, Lomas, D.A, Irving, J.A. | 登録日 | 2018-06-27 | 公開日 | 2019-07-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Characterisation of a monoclonal antibody conformationally-selective for native alpha-1-antitrypsin To Be Published
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5HPO
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![BU of 5hpo by Molmil](/molmil-images/mine/5hpo) | Cycloalternan-forming enzyme from Listeria monocytogenes in complex with maltopentaose | 分子名称: | CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Halavaty, A.S, Light, S.H, Minasov, G, Winsor, J, Grimshaw, S, Shuvalova, L, Peterson, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-01-20 | 公開日 | 2017-01-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Transferase Versus Hydrolase: The Role of Conformational Flexibility in Reaction Specificity. Structure, 25, 2017
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2R0I
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![BU of 2r0i by Molmil](/molmil-images/mine/2r0i) | |
6GJU
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![BU of 6gju by Molmil](/molmil-images/mine/6gju) | human NBD1 of CFTR in complex with nanobodies T2a and T4 | 分子名称: | Cystic fibrosis transmembrane conductance regulator, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C. | 登録日 | 2018-05-17 | 公開日 | 2019-06-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Domain-interface dynamics of CFTR revealed by stabilizing nanobodies. Nat Commun, 10, 2019
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5DY9
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![BU of 5dy9 by Molmil](/molmil-images/mine/5dy9) | Y68T Hfq from Methanococcus jannaschii in complex with AMP | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... | 著者 | Nikulin, A.D, Mikhailina, A.O, Lekontseva, N.V, Balobanov, V.A, Nikonova, E.Y, Tishchenko, S.V. | 登録日 | 2015-09-24 | 公開日 | 2016-09-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Characterization of RNA-binding properties of the archaeal Hfq-like protein from Methanococcus jannaschii. J. Biomol. Struct. Dyn., 35, 2017
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1TBG
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![BU of 1tbg by Molmil](/molmil-images/mine/1tbg) | BETA-GAMMA DIMER OF THE HETEROTRIMERIC G-PROTEIN TRANSDUCIN | 分子名称: | TRANSDUCIN | 著者 | Sondek, J.S, Bohm, A, Lambright, D.G, Hamm, H.E, Sigler, P.B. | 登録日 | 1996-06-15 | 公開日 | 1997-04-01 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of a G-protein beta gamma dimer at 2.1A resolution. Nature, 379, 1996
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6N17
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![BU of 6n17 by Molmil](/molmil-images/mine/6n17) | Crystal structure of Tdp1 catalytic domain in complex with compound XZ577 | 分子名称: | 1,2-ETHANEDIOL, 4-[(3-carboxypropanoyl)amino]benzene-1,2-dicarboxylic acid, DIMETHYL SULFOXIDE, ... | 著者 | Lountos, G.T, Zhao, X.Z, Kiselev, E, Tropea, J.E, Needle, D, Burke Jr, T.R, Pommier, Y, Waugh, D.S. | 登録日 | 2018-11-08 | 公開日 | 2019-07-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.639 Å) | 主引用文献 | Identification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment cocktail screening. Nucleic Acids Res., 47, 2019
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6NXL
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![BU of 6nxl by Molmil](/molmil-images/mine/6nxl) | Ubiquitin binding variants | 分子名称: | Polyubiquitin-B | 著者 | Miller, D.J, Watson, E.R. | 登録日 | 2019-02-08 | 公開日 | 2020-01-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.803 Å) | 主引用文献 | Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site. Proc.Natl.Acad.Sci.USA, 116, 2019
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3I7C
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![BU of 3i7c by Molmil](/molmil-images/mine/3i7c) | |
1NES
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![BU of 1nes by Molmil](/molmil-images/mine/1nes) | STRUCTURE OF THE PRODUCT COMPLEX OF ACETYL-ALA-PRO-ALA WITH PORCINE PANCREATIC ELASTASE AT 1.65 ANGSTROMS RESOLUTION | 分子名称: | ACETYL-ALA-PRO-ALA, CALCIUM ION, ELASTASE, ... | 著者 | Meyer Junior, E.F, Radhakrishnan, R, M Cole, G, Presta, L.G. | 登録日 | 1995-07-31 | 公開日 | 1996-01-29 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structure of the product complex of acetyl-Ala-Pro-Ala with porcine pancreatic elastase at 1.65 A resolution. J.Mol.Biol., 189, 1986
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