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6GXX

Fab fragment of an antibody selective for alpha-1-antitrypsin in the native conformation

Summary for 6GXX
Entry DOI10.2210/pdb6gxx/pdb
DescriptorFAB 1D9 heavy chain, FAB 1D9 light chain, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsantibody fragment, antitrypsin binding, diagnostic, monoclonal, protein binding, conformationally-selective
Biological sourceMus musculus (house mouse)
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Total number of polymer chains2
Total formula weight48044.64
Authors
Elliston, E.L.K.,Miranda, E.,Perez, J.,Lomas, D.A.,Irving, J.A. (deposition date: 2018-06-27, release date: 2019-07-10, Last modification date: 2024-01-17)
Primary citationElliston, E.L.K.,Miranda, E.,Perez, J.,Irving, J.A.,Lomas, D.A.
Characterisation of a monoclonal antibody conformationally-selective for native alpha-1-antitrypsin
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

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