6NXL

Ubiquitin binding variants

Summary for 6NXL

• Entry DOI: 10.2210/pdb6nxl/pdb
• Descriptor: Polyubiquitin-B (1 entity in total)
• Functional Keywords: apc, ubv, ubiquitin, inhibitor, ligase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 8
• Total formula weight: 71168.58

Authors

Miller, D.J.,Watson, E.R. (deposition date: 2019-02-08, release date: 2020-01-15, Last modification date: 2023-10-11)

• Primary citation: Watson, E.R.,Grace, C.R.R.,Zhang, W.,Miller, D.J.,Davidson, I.F.,Prabu, J.R.,Yu, S.,Bolhuis, D.L.,Kulko, E.T.,Vollrath, R.,Haselbach, D.,Stark, H.,Peters, J.M.,Brown, N.G.,Sidhu, S.S.,Schulman, B.A.; Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site.; Proc.Natl.Acad.Sci.USA, 116:17280-17289, 2019; PubMed: 31350353; DOI: 10.1073/pnas.1902889116

Experimental method

X-RAY DIFFRACTION (2.803 Å)