7VJ0
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![BU of 7vj0 by Molmil](/molmil-images/mine/7vj0) | class II photolyase MmCPDII oxidized to semiquinone TR-SFX studies (1 us time-point) | 分子名称: | DNA photolyase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION | 著者 | Maestre-Reyna, M, Yang, C.-H, Huang, W.-C, Nango, E, Ngura Putu, E.P.G, Franz-Badur, S, Wu, W.-J, Wu, H.-Y, Wang, P.-H, Hosokawa, Y, Saft, M, Emmerich, H.-J, Liao, J.-H, Lee, C.-C, Huang, K.-F, Chang, Y.-K, Weng, J.-H, Royant, A, Gad, W, Pang, A.H, Chang, C.-W, Sugahara, M, Owada, S, Joti, Y, Yamashita, A, Tanaka, R, Tanaka, T, Luo, F.J, Tono, K, Kiontke, S, Yamamoto, J, Iwata, S, Essen, L.-O, Bessho, Y, Tsai, M.-D. | 登録日 | 2021-09-28 | 公開日 | 2022-03-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Serial crystallography captures dynamic control of sequential electron and proton transfer events in a flavoenzyme. Nat.Chem., 14, 2022
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7VJA
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![BU of 7vja by Molmil](/molmil-images/mine/7vja) | class II photolyase MmCPDII semiquinone to fully reduced TR-SFX studies (10 ns time-point) | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, DNA photolyase, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Maestre-Reyna, M, Yang, C.-H, Huang, W.-C, Nango, E, Ngura Putu, E.P.G, Franz-Badur, S, Wu, W.-J, Wu, H.-Y, Wang, P.-H, Hosokawa, Y, Saft, M, Emmerich, H.-J, Liao, J.-H, Lee, C.-C, Huang, K.-F, Chang, Y.-K, Weng, J.-H, Royant, A, Gad, W, Pang, A.H, Chang, C.-W, Sugahara, M, Owada, S, Joti, Y, Yamashita, A, Tanaka, R, Tanaka, T, Luo, F.J, Tono, K, Kiontke, S, Yamamoto, J, Iwata, S, Essen, L.-O, Bessho, Y, Tsai, M.-D. | 登録日 | 2021-09-28 | 公開日 | 2022-03-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Serial crystallography captures dynamic control of sequential electron and proton transfer events in a flavoenzyme. Nat.Chem., 14, 2022
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6HKW
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![BU of 6hkw by Molmil](/molmil-images/mine/6hkw) | Crystal structure of human SDS22 | 分子名称: | Protein phosphatase 1 regulatory subunit 7, SULFATE ION | 著者 | Heroes, E, Choy, M.S, Page, R, Peti, W, Ulens, C, Van Meervelt, L, Nys, M, Bollen, M. | 登録日 | 2018-09-09 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Structure-Guided Exploration of SDS22 Interactions with Protein Phosphatase PP1 and the Splicing Factor BCLAF1. Structure, 27, 2019
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7VIX
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![BU of 7vix by Molmil](/molmil-images/mine/7vix) | class II photolyase MmCPDII oxidized to semiquinone TR-SFX studies (10 ns time-point) | 分子名称: | DNA photolyase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION | 著者 | Maestre-Reyna, M, Yang, C.-H, Huang, W.-C, Nango, E, Ngura Putu, E.P.G, Franz-Badur, S, Wu, W.-J, Wu, H.-Y, Wang, P.-H, Hosokawa, Y, Saft, M, Emmerich, H.-J, Liao, J.-H, Lee, C.-C, Huang, K.-F, Chang, Y.-K, Weng, J.-H, Royant, A, Gad, W, Pang, A.H, Chang, C.-W, Sugahara, M, Owada, S, Joti, Y, Yamashita, A, Tanaka, R, Tanaka, T, Luo, F.J, Tono, K, Kiontke, S, Yamamoto, J, Iwata, S, Essen, L.-O, Bessho, Y, Tsai, M.-D. | 登録日 | 2021-09-28 | 公開日 | 2022-03-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Serial crystallography captures dynamic control of sequential electron and proton transfer events in a flavoenzyme. Nat.Chem., 14, 2022
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7VJ7
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![BU of 7vj7 by Molmil](/molmil-images/mine/7vj7) | SFX structure of archaeal class II CPD photolyase from Methanosarcina mazei in the fully reduced state | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, DNA photolyase, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Maestre-Reyna, M, Yang, C.-H, Huang, W.C, Nango, E, Gusti-Ngurah-Putu, E.-P, Franz-Badur, S, Wu, W.-J, Wu, H.-Y, Wang, P.-H, Liao, J.-H, Lee, C.-C, Huang, K.-F, Chang, Y.-K, Weng, J.-H, Sugahara, M, Owada, S, Joti, Y, Tanaka, R, Tono, K, Kiontke, S, Yamamoto, J, Iwata, S, Essen, L.-O, Bessho, Y, Tsai, M.-D. | 登録日 | 2021-09-28 | 公開日 | 2022-03-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Serial crystallography captures dynamic control of sequential electron and proton transfer events in a flavoenzyme. Nat.Chem., 14, 2022
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7VJJ
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![BU of 7vjj by Molmil](/molmil-images/mine/7vjj) | class II photolyase MmCPDII semiquinone to fully reduced TR-SFX studies (30 us time-point) | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, DNA photolyase, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Maestre-Reyna, M, Yang, C.-H, Huang, W.-C, Nango, E, Ngura Putu, E.P.G, Franz-Badur, S, Wu, W.-J, Wu, H.-Y, Wang, P.-H, Hosokawa, Y, Saft, M, Emmerich, H.-J, Liao, J.-H, Lee, C.-C, Huang, K.-F, Chang, Y.-K, Weng, J.-H, Royant, A, Gad, W, Pang, A.H, Chang, C.-W, Sugahara, M, Owada, S, Joti, Y, Yamashita, A, Tanaka, R, Tanaka, T, Luo, F.J, Tono, K, Kiontke, S, Yamamoto, J, Iwata, S, Essen, L.-O, Bessho, Y, Tsai, M.-D. | 登録日 | 2021-09-28 | 公開日 | 2022-03-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Serial crystallography captures dynamic control of sequential electron and proton transfer events in a flavoenzyme. Nat.Chem., 14, 2022
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4ZF8
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![BU of 4zf8 by Molmil](/molmil-images/mine/4zf8) | Cytochrome P450 pentamutant from BM3 with bound Metyrapone | 分子名称: | Bifunctional P-450/NADPH-P450 reductase, METYRAPONE, NICKEL (II) ION, ... | 著者 | Rogers, W.E, Othman, T, Heidary, D.K, Huxford, T. | 登録日 | 2015-04-21 | 公開日 | 2016-07-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.766 Å) | 主引用文献 | Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants. Biochemistry, 55, 2016
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6N9J
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4BUJ
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![BU of 4buj by Molmil](/molmil-images/mine/4buj) | Crystal structure of the S. cerevisiae Ski2-3-8 complex | 分子名称: | ANTIVIRAL HELICASE SKI2, ANTIVIRAL PROTEIN SKI8, SULFATE ION, ... | 著者 | Halbach, F, Reichelt, P, Rode, M, Conti, E. | 登録日 | 2013-06-20 | 公開日 | 2013-08-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | The Yeast Ski Complex: Crystal Structure and RNA Channeling to the Exosome Complex. Cell(Cambridge,Mass.), 154, 2013
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8F4R
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![BU of 8f4r by Molmil](/molmil-images/mine/8f4r) | Gentamicin bound aminoglycoside efflux pump AcrD | 分子名称: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, Efflux pump membrane transporter | 著者 | Zhang, Z. | 登録日 | 2022-11-11 | 公開日 | 2022-12-28 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity. Mbio, 14, 2023
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7ZYA
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8A43
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![BU of 8a43 by Molmil](/molmil-images/mine/8a43) | Human RNA polymerase I | 分子名称: | DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA2, ... | 著者 | Daiss, J.L, Pilsl, M, Straub, K, Bleckmann, A, Hoecherl, M, Heiss, F.B, Abascal-Palacios, G, Ramsay, E, Tluckova, K, Mars, J.C, Fuertges, T, Bruckmann, A, Rudack, T, Bernecky, C, Lamour, V, Panov, K, Vannini, A, Moss, T, Engel, C. | 登録日 | 2022-06-10 | 公開日 | 2022-08-31 | 最終更新日 | 2022-11-02 | 実験手法 | ELECTRON MICROSCOPY (4.09 Å) | 主引用文献 | The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans. Life Sci Alliance, 5, 2022
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5BSI
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3HP6
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6ANU
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![BU of 6anu by Molmil](/molmil-images/mine/6anu) | Cryo-EM structure of F-actin complexed with the beta-III-spectrin actin-binding domain | 分子名称: | Actin, cytoplasmic 1, Spectrin beta chain, ... | 著者 | Wang, F, Orlova, A, Avery, A.W, Hays, T.S, Egelman, E.H. | 登録日 | 2017-08-14 | 公開日 | 2017-11-22 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Structural basis for high-affinity actin binding revealed by a beta-III-spectrin SCA5 missense mutation. Nat Commun, 8, 2017
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1AT1
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5I74
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![BU of 5i74 by Molmil](/molmil-images/mine/5i74) | X-ray structure of the ts3 human serotonin transporter complexed with Br-citalopram at the central site | 分子名称: | (1S)-1-(4-bromophenyl)-1-[3-(dimethylamino)propyl]-1,3-dihydro-2-benzofuran-5-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, ... | 著者 | Coleman, J.A, Green, E.M, Gouaux, E. | 登録日 | 2016-02-16 | 公開日 | 2016-04-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.395 Å) | 主引用文献 | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
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6GFY
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![BU of 6gfy by Molmil](/molmil-images/mine/6gfy) | pVHL:EloB:EloC in complex with modified VH032 containing (3R,4S)-3-fluoro-4-hydroxyproline (ligand 14a) | 分子名称: | (2~{R},3~{R},4~{S})-1-[(2~{S})-2-acetamido-3,3-dimethyl-butanoyl]-3-fluoranyl-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | 著者 | Gadd, M.S, Testa, A, Ciulli, A. | 登録日 | 2018-05-02 | 公開日 | 2018-07-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | 3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation. J. Am. Chem. Soc., 140, 2018
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8A3G
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![BU of 8a3g by Molmil](/molmil-images/mine/8a3g) | X-ray crystal structure of a de novo designed antiparallel coiled-coil homotetramer with 4 heptad repeats, apCC-Tet* | 分子名称: | ACETATE ION, SODIUM ION, apCC-Tet* | 著者 | Naudin, E.A, Mylemans, B, Albanese, K.I, Woolfson, D.N. | 登録日 | 2022-06-08 | 公開日 | 2022-10-05 | 最終更新日 | 2022-11-23 | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | 主引用文献 | From peptides to proteins: coiled-coil tetramers to single-chain 4-helix bundles. Chem Sci, 13, 2022
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6TQJ
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![BU of 6tqj by Molmil](/molmil-images/mine/6tqj) | Crystal structure of the c14 ring of the F1FO ATP synthase from spinach chloroplast | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ATP synthase subunit c, chloroplastic, ... | 著者 | Kovalev, K, Gushchin, I, Vlasov, A, Round, E, Polovinkin, V, Gordeliy, V. | 登録日 | 2019-12-16 | 公開日 | 2019-12-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Unusual features of the c-ring of F1FOATP synthases. Sci Rep, 9, 2019
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2AID
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![BU of 2aid by Molmil](/molmil-images/mine/2aid) | STRUCTURE OF A NON-PEPTIDE INHIBITOR COMPLEXED WITH HIV-1 PROTEASE: DEVELOPING A CYCLE OF STRUCTURE-BASED DRUG DESIGN | 分子名称: | 4-(4-CHLORO-PHENYL)-1-{3-[2-(4-FLUORO-PHENYL)-[1,3]DITHIOLAN-2-YL]-PROPYL}-PIPERIDIN-4-OL, CHLORIDE ION, HUMAN IMMUNODEFICIENCY VIRUS PROTEASE | 著者 | Rutenber, E.E, Fauman, E.B, Keenan, R.J, Stroud, R.M. | 登録日 | 1997-04-17 | 公開日 | 1997-10-15 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of a non-peptide inhibitor complexed with HIV-1 protease. Developing a cycle of structure-based drug design. J.Biol.Chem., 268, 1993
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8B3E
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![BU of 8b3e by Molmil](/molmil-images/mine/8b3e) | Variant Surface Glycoprotein VSG397 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein 397 | 著者 | Zeelen, J.P, Stebbins, C.E, Dakovic, S, Foti, K. | 登録日 | 2022-09-16 | 公開日 | 2023-01-25 | 最終更新日 | 2023-04-19 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome. Plos Negl Trop Dis, 17, 2023
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5I71
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![BU of 5i71 by Molmil](/molmil-images/mine/5i71) | X-ray structure of the ts3 human serotonin transporter complexed with s-citalopram at the central site | 分子名称: | (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, ... | 著者 | Coleman, J.A, Green, E.M, Gouaux, E. | 登録日 | 2016-02-16 | 公開日 | 2016-04-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
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8PDE
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![BU of 8pde by Molmil](/molmil-images/mine/8pde) | Crystal Structure of the MADS-box/MEF2 Domain of MEF2D bound to dsDNA and HDAC4 deacetylase binding motif | 分子名称: | DNA (5'-D(P*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*A)-3'), DNA (5'-D(P*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*TP*T)-3'), HDAC4 (histone deacetylase 4) binding motif peptide:GSGEVKMKLQEFVLNKK, ... | 著者 | Chinellato, M, Carli, A, Perin, S, Mazzocato, Y, Biondi, B, Di Giorgio, E, Brancolini, C, Angelini, A, Cendron, L. | 登録日 | 2023-06-12 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA. J.Mol.Biol., 436, 2024
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4ER0
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![BU of 4er0 by Molmil](/molmil-images/mine/4er0) | Crystal Structure of human DOT1L in complex with inhibitor FED1 | 分子名称: | 5'-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5'-deoxyadenosine, Histone-lysine N-methyltransferase, H3 lysine-79 specific, ... | 著者 | Wernimont, A.K, Tempel, W, Yu, W, Li, Y, Nguyen, K.T, Federation, A, Marineau, J, Qi, J, Vedadi, M, Bradner, J.E, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Brown, P.J, Structural Genomics Consortium (SGC) | 登録日 | 2012-04-19 | 公開日 | 2012-05-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Nat Commun, 3, 2012
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