6ANU

Cryo-EM structure of F-actin complexed with the beta-III-spectrin actin-binding domain

Summary for 6ANU

• Entry DOI: 10.2210/pdb6anu/pdb
• EMDB information: 8886
• Descriptor: Actin, cytoplasmic 1, Spectrin beta chain, non-erythrocytic 2 (2 entities in total)
• Functional Keywords: actin binding protein, filament, structural protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 447838.81

Authors

Wang, F.,Orlova, A.,Avery, A.W.,Hays, T.S.,Egelman, E.H. (deposition date: 2017-08-14, release date: 2017-11-22, Last modification date: 2024-03-13)

• Primary citation: Avery, A.W.,Fealey, M.E.,Wang, F.,Orlova, A.,Thompson, A.R.,Thomas, D.D.,Hays, T.S.,Egelman, E.H.; Structural basis for high-affinity actin binding revealed by a beta-III-spectrin SCA5 missense mutation.; Nat Commun, 8:1350-1350, 2017; PubMed: 29116080; DOI: 10.1038/s41467-017-01367-w

Experimental method

ELECTRON MICROSCOPY (7 Å)