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6ANU

Cryo-EM structure of F-actin complexed with the beta-III-spectrin actin-binding domain

Functional Information from GO Data
ChainGOidnamespacecontents
A0000079biological_processregulation of cyclin-dependent protein serine/threonine kinase activity
A0000776cellular_componentkinetochore
A0000785cellular_componentchromatin
A0000786cellular_componentnucleosome
A0001738biological_processmorphogenesis of a polarized epithelium
A0005200molecular_functionstructural constituent of cytoskeleton
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005615cellular_componentextracellular space
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005884cellular_componentactin filament
A0005886cellular_componentplasma membrane
A0005903cellular_componentbrush border
A0005911cellular_componentcell-cell junction
A0005912cellular_componentadherens junction
A0005925cellular_componentfocal adhesion
A0006338biological_processchromatin remodeling
A0006357biological_processregulation of transcription by RNA polymerase II
A0007010biological_processcytoskeleton organization
A0007163biological_processestablishment or maintenance of cell polarity
A0007409biological_processaxonogenesis
A0008284biological_processpositive regulation of cell population proliferation
A0015629cellular_componentactin cytoskeleton
A0016020cellular_componentmembrane
A0016363cellular_componentnuclear matrix
A0016514cellular_componentSWI/SNF complex
A0016586cellular_componentRSC-type complex
A0016787molecular_functionhydrolase activity
A0016887molecular_functionATP hydrolysis activity
A0019894molecular_functionkinesin binding
A0019901molecular_functionprotein kinase binding
A0021762biological_processsubstantia nigra development
A0022898biological_processregulation of transmembrane transporter activity
A0030027cellular_componentlamellipodium
A0030071biological_processregulation of mitotic metaphase/anaphase transition
A0030424cellular_componentaxon
A0030863cellular_componentcortical cytoskeleton
A0030957molecular_functionTat protein binding
A0031492molecular_functionnucleosomal DNA binding
A0031982cellular_componentvesicle
A0032091biological_processnegative regulation of protein binding
A0032991cellular_componentprotein-containing complex
A0034333biological_processadherens junction assembly
A0035060cellular_componentbrahma complex
A0035267cellular_componentNuA4 histone acetyltransferase complex
A0035633biological_processmaintenance of blood-brain barrier
A0036464cellular_componentcytoplasmic ribonucleoprotein granule
A0042802molecular_functionidentical protein binding
A0042981biological_processregulation of apoptotic process
A0043296cellular_componentapical junction complex
A0044305cellular_componentcalyx of Held
A0045176biological_processapical protein localization
A0045202cellular_componentsynapse
A0045582biological_processpositive regulation of T cell differentiation
A0045596biological_processnegative regulation of cell differentiation
A0045597biological_processpositive regulation of cell differentiation
A0045663biological_processpositive regulation of myoblast differentiation
A0045893biological_processpositive regulation of DNA-templated transcription
A0048156molecular_functiontau protein binding
A0048870biological_processcell motility
A0050998molecular_functionnitric-oxide synthase binding
A0051621biological_processregulation of norepinephrine uptake
A0051623biological_processpositive regulation of norepinephrine uptake
A0051726biological_processregulation of cell cycle
A0070062cellular_componentextracellular exosome
A0070160cellular_componenttight junction
A0070316biological_processregulation of G0 to G1 transition
A0070527biological_processplatelet aggregation
A0071564cellular_componentnpBAF complex
A0071565cellular_componentnBAF complex
A0071896biological_processprotein localization to adherens junction
A0072562cellular_componentblood microparticle
A0072749biological_processcellular response to cytochalasin B
A0097433cellular_componentdense body
A0098685cellular_componentSchaffer collateral - CA1 synapse
A0098793cellular_componentpresynapse
A0098871cellular_componentpostsynaptic actin cytoskeleton
A0098973molecular_functionstructural constituent of postsynaptic actin cytoskeleton
A0098974biological_processpostsynaptic actin cytoskeleton organization
A0098978cellular_componentglutamatergic synapse
A0140092cellular_componentbBAF complex
A0140288cellular_componentGBAF complex
A0150111biological_processregulation of transepithelial transport
A1900242biological_processregulation of synaptic vesicle endocytosis
A1902459biological_processpositive regulation of stem cell population maintenance
A1903076biological_processregulation of protein localization to plasma membrane
A1905168biological_processpositive regulation of double-strand break repair via homologous recombination
A1990904cellular_componentribonucleoprotein complex
A2000045biological_processregulation of G1/S transition of mitotic cell cycle
A2000779biological_processregulation of double-strand break repair
A2000781biological_processpositive regulation of double-strand break repair
A2000819biological_processregulation of nucleotide-excision repair
B0000079biological_processregulation of cyclin-dependent protein serine/threonine kinase activity
B0000776cellular_componentkinetochore
B0000785cellular_componentchromatin
B0000786cellular_componentnucleosome
B0001738biological_processmorphogenesis of a polarized epithelium
B0005200molecular_functionstructural constituent of cytoskeleton
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005615cellular_componentextracellular space
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0005884cellular_componentactin filament
B0005886cellular_componentplasma membrane
B0005903cellular_componentbrush border
B0005911cellular_componentcell-cell junction
B0005912cellular_componentadherens junction
B0005925cellular_componentfocal adhesion
B0006338biological_processchromatin remodeling
B0006357biological_processregulation of transcription by RNA polymerase II
B0007010biological_processcytoskeleton organization
B0007163biological_processestablishment or maintenance of cell polarity
B0007409biological_processaxonogenesis
B0008284biological_processpositive regulation of cell population proliferation
B0015629cellular_componentactin cytoskeleton
B0016020cellular_componentmembrane
B0016363cellular_componentnuclear matrix
B0016514cellular_componentSWI/SNF complex
B0016586cellular_componentRSC-type complex
B0016787molecular_functionhydrolase activity
B0016887molecular_functionATP hydrolysis activity
B0019894molecular_functionkinesin binding
B0019901molecular_functionprotein kinase binding
B0021762biological_processsubstantia nigra development
B0022898biological_processregulation of transmembrane transporter activity
B0030027cellular_componentlamellipodium
B0030071biological_processregulation of mitotic metaphase/anaphase transition
B0030424cellular_componentaxon
B0030863cellular_componentcortical cytoskeleton
B0030957molecular_functionTat protein binding
B0031492molecular_functionnucleosomal DNA binding
B0031982cellular_componentvesicle
B0032091biological_processnegative regulation of protein binding
B0032991cellular_componentprotein-containing complex
B0034333biological_processadherens junction assembly
B0035060cellular_componentbrahma complex
B0035267cellular_componentNuA4 histone acetyltransferase complex
B0035633biological_processmaintenance of blood-brain barrier
B0036464cellular_componentcytoplasmic ribonucleoprotein granule
B0042802molecular_functionidentical protein binding
B0042981biological_processregulation of apoptotic process
B0043296cellular_componentapical junction complex
B0044305cellular_componentcalyx of Held
B0045176biological_processapical protein localization
B0045202cellular_componentsynapse
B0045582biological_processpositive regulation of T cell differentiation
B0045596biological_processnegative regulation of cell differentiation
B0045597biological_processpositive regulation of cell differentiation
B0045663biological_processpositive regulation of myoblast differentiation
B0045893biological_processpositive regulation of DNA-templated transcription
B0048156molecular_functiontau protein binding
B0048870biological_processcell motility
B0050998molecular_functionnitric-oxide synthase binding
B0051621biological_processregulation of norepinephrine uptake
B0051623biological_processpositive regulation of norepinephrine uptake
B0051726biological_processregulation of cell cycle
B0070062cellular_componentextracellular exosome
B0070160cellular_componenttight junction
B0070316biological_processregulation of G0 to G1 transition
B0070527biological_processplatelet aggregation
B0071564cellular_componentnpBAF complex
B0071565cellular_componentnBAF complex
B0071896biological_processprotein localization to adherens junction
B0072562cellular_componentblood microparticle
B0072749biological_processcellular response to cytochalasin B
B0097433cellular_componentdense body
B0098685cellular_componentSchaffer collateral - CA1 synapse
B0098793cellular_componentpresynapse
B0098871cellular_componentpostsynaptic actin cytoskeleton
B0098973molecular_functionstructural constituent of postsynaptic actin cytoskeleton
B0098974biological_processpostsynaptic actin cytoskeleton organization
B0098978cellular_componentglutamatergic synapse
B0140092cellular_componentbBAF complex
B0140288cellular_componentGBAF complex
B0150111biological_processregulation of transepithelial transport
B1900242biological_processregulation of synaptic vesicle endocytosis
B1902459biological_processpositive regulation of stem cell population maintenance
B1903076biological_processregulation of protein localization to plasma membrane
B1905168biological_processpositive regulation of double-strand break repair via homologous recombination
B1990904cellular_componentribonucleoprotein complex
B2000045biological_processregulation of G1/S transition of mitotic cell cycle
B2000779biological_processregulation of double-strand break repair
B2000781biological_processpositive regulation of double-strand break repair
B2000819biological_processregulation of nucleotide-excision repair
C0000079biological_processregulation of cyclin-dependent protein serine/threonine kinase activity
C0000776cellular_componentkinetochore
C0000785cellular_componentchromatin
C0000786cellular_componentnucleosome
C0001738biological_processmorphogenesis of a polarized epithelium
C0005200molecular_functionstructural constituent of cytoskeleton
C0005515molecular_functionprotein binding
C0005524molecular_functionATP binding
C0005615cellular_componentextracellular space
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005856cellular_componentcytoskeleton
C0005884cellular_componentactin filament
C0005886cellular_componentplasma membrane
C0005903cellular_componentbrush border
C0005911cellular_componentcell-cell junction
C0005912cellular_componentadherens junction
C0005925cellular_componentfocal adhesion
C0006338biological_processchromatin remodeling
C0006357biological_processregulation of transcription by RNA polymerase II
C0007010biological_processcytoskeleton organization
C0007163biological_processestablishment or maintenance of cell polarity
C0007409biological_processaxonogenesis
C0008284biological_processpositive regulation of cell population proliferation
C0015629cellular_componentactin cytoskeleton
C0016020cellular_componentmembrane
C0016363cellular_componentnuclear matrix
C0016514cellular_componentSWI/SNF complex
C0016586cellular_componentRSC-type complex
C0016787molecular_functionhydrolase activity
C0016887molecular_functionATP hydrolysis activity
C0019894molecular_functionkinesin binding
C0019901molecular_functionprotein kinase binding
C0021762biological_processsubstantia nigra development
C0022898biological_processregulation of transmembrane transporter activity
C0030027cellular_componentlamellipodium
C0030071biological_processregulation of mitotic metaphase/anaphase transition
C0030424cellular_componentaxon
C0030863cellular_componentcortical cytoskeleton
C0030957molecular_functionTat protein binding
C0031492molecular_functionnucleosomal DNA binding
C0031982cellular_componentvesicle
C0032091biological_processnegative regulation of protein binding
C0032991cellular_componentprotein-containing complex
C0034333biological_processadherens junction assembly
C0035060cellular_componentbrahma complex
C0035267cellular_componentNuA4 histone acetyltransferase complex
C0035633biological_processmaintenance of blood-brain barrier
C0036464cellular_componentcytoplasmic ribonucleoprotein granule
C0042802molecular_functionidentical protein binding
C0042981biological_processregulation of apoptotic process
C0043296cellular_componentapical junction complex
C0044305cellular_componentcalyx of Held
C0045176biological_processapical protein localization
C0045202cellular_componentsynapse
C0045582biological_processpositive regulation of T cell differentiation
C0045596biological_processnegative regulation of cell differentiation
C0045597biological_processpositive regulation of cell differentiation
C0045663biological_processpositive regulation of myoblast differentiation
C0045893biological_processpositive regulation of DNA-templated transcription
C0048156molecular_functiontau protein binding
C0048870biological_processcell motility
C0050998molecular_functionnitric-oxide synthase binding
C0051621biological_processregulation of norepinephrine uptake
C0051623biological_processpositive regulation of norepinephrine uptake
C0051726biological_processregulation of cell cycle
C0070062cellular_componentextracellular exosome
C0070160cellular_componenttight junction
C0070316biological_processregulation of G0 to G1 transition
C0070527biological_processplatelet aggregation
C0071564cellular_componentnpBAF complex
C0071565cellular_componentnBAF complex
C0071896biological_processprotein localization to adherens junction
C0072562cellular_componentblood microparticle
C0072749biological_processcellular response to cytochalasin B
C0097433cellular_componentdense body
C0098685cellular_componentSchaffer collateral - CA1 synapse
C0098793cellular_componentpresynapse
C0098871cellular_componentpostsynaptic actin cytoskeleton
C0098973molecular_functionstructural constituent of postsynaptic actin cytoskeleton
C0098974biological_processpostsynaptic actin cytoskeleton organization
C0098978cellular_componentglutamatergic synapse
C0140092cellular_componentbBAF complex
C0140288cellular_componentGBAF complex
C0150111biological_processregulation of transepithelial transport
C1900242biological_processregulation of synaptic vesicle endocytosis
C1902459biological_processpositive regulation of stem cell population maintenance
C1903076biological_processregulation of protein localization to plasma membrane
C1905168biological_processpositive regulation of double-strand break repair via homologous recombination
C1990904cellular_componentribonucleoprotein complex
C2000045biological_processregulation of G1/S transition of mitotic cell cycle
C2000779biological_processregulation of double-strand break repair
C2000781biological_processpositive regulation of double-strand break repair
C2000819biological_processregulation of nucleotide-excision repair
D0000079biological_processregulation of cyclin-dependent protein serine/threonine kinase activity
D0000776cellular_componentkinetochore
D0000785cellular_componentchromatin
D0000786cellular_componentnucleosome
D0001738biological_processmorphogenesis of a polarized epithelium
D0005200molecular_functionstructural constituent of cytoskeleton
D0005515molecular_functionprotein binding
D0005524molecular_functionATP binding
D0005615cellular_componentextracellular space
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0005856cellular_componentcytoskeleton
D0005884cellular_componentactin filament
D0005886cellular_componentplasma membrane
D0005903cellular_componentbrush border
D0005911cellular_componentcell-cell junction
D0005912cellular_componentadherens junction
D0005925cellular_componentfocal adhesion
D0006338biological_processchromatin remodeling
D0006357biological_processregulation of transcription by RNA polymerase II
D0007010biological_processcytoskeleton organization
D0007163biological_processestablishment or maintenance of cell polarity
D0007409biological_processaxonogenesis
D0008284biological_processpositive regulation of cell population proliferation
D0015629cellular_componentactin cytoskeleton
D0016020cellular_componentmembrane
D0016363cellular_componentnuclear matrix
D0016514cellular_componentSWI/SNF complex
D0016586cellular_componentRSC-type complex
D0016787molecular_functionhydrolase activity
D0016887molecular_functionATP hydrolysis activity
D0019894molecular_functionkinesin binding
D0019901molecular_functionprotein kinase binding
D0021762biological_processsubstantia nigra development
D0022898biological_processregulation of transmembrane transporter activity
D0030027cellular_componentlamellipodium
D0030071biological_processregulation of mitotic metaphase/anaphase transition
D0030424cellular_componentaxon
D0030863cellular_componentcortical cytoskeleton
D0030957molecular_functionTat protein binding
D0031492molecular_functionnucleosomal DNA binding
D0031982cellular_componentvesicle
D0032091biological_processnegative regulation of protein binding
D0032991cellular_componentprotein-containing complex
D0034333biological_processadherens junction assembly
D0035060cellular_componentbrahma complex
D0035267cellular_componentNuA4 histone acetyltransferase complex
D0035633biological_processmaintenance of blood-brain barrier
D0036464cellular_componentcytoplasmic ribonucleoprotein granule
D0042802molecular_functionidentical protein binding
D0042981biological_processregulation of apoptotic process
D0043296cellular_componentapical junction complex
D0044305cellular_componentcalyx of Held
D0045176biological_processapical protein localization
D0045202cellular_componentsynapse
D0045582biological_processpositive regulation of T cell differentiation
D0045596biological_processnegative regulation of cell differentiation
D0045597biological_processpositive regulation of cell differentiation
D0045663biological_processpositive regulation of myoblast differentiation
D0045893biological_processpositive regulation of DNA-templated transcription
D0048156molecular_functiontau protein binding
D0048870biological_processcell motility
D0050998molecular_functionnitric-oxide synthase binding
D0051621biological_processregulation of norepinephrine uptake
D0051623biological_processpositive regulation of norepinephrine uptake
D0051726biological_processregulation of cell cycle
D0070062cellular_componentextracellular exosome
D0070160cellular_componenttight junction
D0070316biological_processregulation of G0 to G1 transition
D0070527biological_processplatelet aggregation
D0071564cellular_componentnpBAF complex
D0071565cellular_componentnBAF complex
D0071896biological_processprotein localization to adherens junction
D0072562cellular_componentblood microparticle
D0072749biological_processcellular response to cytochalasin B
D0097433cellular_componentdense body
D0098685cellular_componentSchaffer collateral - CA1 synapse
D0098793cellular_componentpresynapse
D0098871cellular_componentpostsynaptic actin cytoskeleton
D0098973molecular_functionstructural constituent of postsynaptic actin cytoskeleton
D0098974biological_processpostsynaptic actin cytoskeleton organization
D0098978cellular_componentglutamatergic synapse
D0140092cellular_componentbBAF complex
D0140288cellular_componentGBAF complex
D0150111biological_processregulation of transepithelial transport
D1900242biological_processregulation of synaptic vesicle endocytosis
D1902459biological_processpositive regulation of stem cell population maintenance
D1903076biological_processregulation of protein localization to plasma membrane
D1905168biological_processpositive regulation of double-strand break repair via homologous recombination
D1990904cellular_componentribonucleoprotein complex
D2000045biological_processregulation of G1/S transition of mitotic cell cycle
D2000779biological_processregulation of double-strand break repair
D2000781biological_processpositive regulation of double-strand break repair
D2000819biological_processregulation of nucleotide-excision repair
E0000079biological_processregulation of cyclin-dependent protein serine/threonine kinase activity
E0000776cellular_componentkinetochore
E0000785cellular_componentchromatin
E0000786cellular_componentnucleosome
E0001738biological_processmorphogenesis of a polarized epithelium
E0005200molecular_functionstructural constituent of cytoskeleton
E0005515molecular_functionprotein binding
E0005524molecular_functionATP binding
E0005615cellular_componentextracellular space
E0005634cellular_componentnucleus
E0005654cellular_componentnucleoplasm
E0005737cellular_componentcytoplasm
E0005829cellular_componentcytosol
E0005856cellular_componentcytoskeleton
E0005884cellular_componentactin filament
E0005886cellular_componentplasma membrane
E0005903cellular_componentbrush border
E0005911cellular_componentcell-cell junction
E0005912cellular_componentadherens junction
E0005925cellular_componentfocal adhesion
E0006338biological_processchromatin remodeling
E0006357biological_processregulation of transcription by RNA polymerase II
E0007010biological_processcytoskeleton organization
E0007163biological_processestablishment or maintenance of cell polarity
E0007409biological_processaxonogenesis
E0008284biological_processpositive regulation of cell population proliferation
E0015629cellular_componentactin cytoskeleton
E0016020cellular_componentmembrane
E0016363cellular_componentnuclear matrix
E0016514cellular_componentSWI/SNF complex
E0016586cellular_componentRSC-type complex
E0016787molecular_functionhydrolase activity
E0016887molecular_functionATP hydrolysis activity
E0019894molecular_functionkinesin binding
E0019901molecular_functionprotein kinase binding
E0021762biological_processsubstantia nigra development
E0022898biological_processregulation of transmembrane transporter activity
E0030027cellular_componentlamellipodium
E0030071biological_processregulation of mitotic metaphase/anaphase transition
E0030424cellular_componentaxon
E0030863cellular_componentcortical cytoskeleton
E0030957molecular_functionTat protein binding
E0031492molecular_functionnucleosomal DNA binding
E0031982cellular_componentvesicle
E0032091biological_processnegative regulation of protein binding
E0032991cellular_componentprotein-containing complex
E0034333biological_processadherens junction assembly
E0035060cellular_componentbrahma complex
E0035267cellular_componentNuA4 histone acetyltransferase complex
E0035633biological_processmaintenance of blood-brain barrier
E0036464cellular_componentcytoplasmic ribonucleoprotein granule
E0042802molecular_functionidentical protein binding
E0042981biological_processregulation of apoptotic process
E0043296cellular_componentapical junction complex
E0044305cellular_componentcalyx of Held
E0045176biological_processapical protein localization
E0045202cellular_componentsynapse
E0045582biological_processpositive regulation of T cell differentiation
E0045596biological_processnegative regulation of cell differentiation
E0045597biological_processpositive regulation of cell differentiation
E0045663biological_processpositive regulation of myoblast differentiation
E0045893biological_processpositive regulation of DNA-templated transcription
E0048156molecular_functiontau protein binding
E0048870biological_processcell motility
E0050998molecular_functionnitric-oxide synthase binding
E0051621biological_processregulation of norepinephrine uptake
E0051623biological_processpositive regulation of norepinephrine uptake
E0051726biological_processregulation of cell cycle
E0070062cellular_componentextracellular exosome
E0070160cellular_componenttight junction
E0070316biological_processregulation of G0 to G1 transition
E0070527biological_processplatelet aggregation
E0071564cellular_componentnpBAF complex
E0071565cellular_componentnBAF complex
E0071896biological_processprotein localization to adherens junction
E0072562cellular_componentblood microparticle
E0072749biological_processcellular response to cytochalasin B
E0097433cellular_componentdense body
E0098685cellular_componentSchaffer collateral - CA1 synapse
E0098793cellular_componentpresynapse
E0098871cellular_componentpostsynaptic actin cytoskeleton
E0098973molecular_functionstructural constituent of postsynaptic actin cytoskeleton
E0098974biological_processpostsynaptic actin cytoskeleton organization
E0098978cellular_componentglutamatergic synapse
E0140092cellular_componentbBAF complex
E0140288cellular_componentGBAF complex
E0150111biological_processregulation of transepithelial transport
E1900242biological_processregulation of synaptic vesicle endocytosis
E1902459biological_processpositive regulation of stem cell population maintenance
E1903076biological_processregulation of protein localization to plasma membrane
E1905168biological_processpositive regulation of double-strand break repair via homologous recombination
E1990904cellular_componentribonucleoprotein complex
E2000045biological_processregulation of G1/S transition of mitotic cell cycle
E2000779biological_processregulation of double-strand break repair
E2000781biological_processpositive regulation of double-strand break repair
E2000819biological_processregulation of nucleotide-excision repair
F0000079biological_processregulation of cyclin-dependent protein serine/threonine kinase activity
F0000776cellular_componentkinetochore
F0000785cellular_componentchromatin
F0000786cellular_componentnucleosome
F0001738biological_processmorphogenesis of a polarized epithelium
F0005200molecular_functionstructural constituent of cytoskeleton
F0005515molecular_functionprotein binding
F0005524molecular_functionATP binding
F0005615cellular_componentextracellular space
F0005634cellular_componentnucleus
F0005654cellular_componentnucleoplasm
F0005737cellular_componentcytoplasm
F0005829cellular_componentcytosol
F0005856cellular_componentcytoskeleton
F0005884cellular_componentactin filament
F0005886cellular_componentplasma membrane
F0005903cellular_componentbrush border
F0005911cellular_componentcell-cell junction
F0005912cellular_componentadherens junction
F0005925cellular_componentfocal adhesion
F0006338biological_processchromatin remodeling
F0006357biological_processregulation of transcription by RNA polymerase II
F0007010biological_processcytoskeleton organization
F0007163biological_processestablishment or maintenance of cell polarity
F0007409biological_processaxonogenesis
F0008284biological_processpositive regulation of cell population proliferation
F0015629cellular_componentactin cytoskeleton
F0016020cellular_componentmembrane
F0016363cellular_componentnuclear matrix
F0016514cellular_componentSWI/SNF complex
F0016586cellular_componentRSC-type complex
F0016787molecular_functionhydrolase activity
F0016887molecular_functionATP hydrolysis activity
F0019894molecular_functionkinesin binding
F0019901molecular_functionprotein kinase binding
F0021762biological_processsubstantia nigra development
F0022898biological_processregulation of transmembrane transporter activity
F0030027cellular_componentlamellipodium
F0030071biological_processregulation of mitotic metaphase/anaphase transition
F0030424cellular_componentaxon
F0030863cellular_componentcortical cytoskeleton
F0030957molecular_functionTat protein binding
F0031492molecular_functionnucleosomal DNA binding
F0031982cellular_componentvesicle
F0032091biological_processnegative regulation of protein binding
F0032991cellular_componentprotein-containing complex
F0034333biological_processadherens junction assembly
F0035060cellular_componentbrahma complex
F0035267cellular_componentNuA4 histone acetyltransferase complex
F0035633biological_processmaintenance of blood-brain barrier
F0036464cellular_componentcytoplasmic ribonucleoprotein granule
F0042802molecular_functionidentical protein binding
F0042981biological_processregulation of apoptotic process
F0043296cellular_componentapical junction complex
F0044305cellular_componentcalyx of Held
F0045176biological_processapical protein localization
F0045202cellular_componentsynapse
F0045582biological_processpositive regulation of T cell differentiation
F0045596biological_processnegative regulation of cell differentiation
F0045597biological_processpositive regulation of cell differentiation
F0045663biological_processpositive regulation of myoblast differentiation
F0045893biological_processpositive regulation of DNA-templated transcription
F0048156molecular_functiontau protein binding
F0048870biological_processcell motility
F0050998molecular_functionnitric-oxide synthase binding
F0051621biological_processregulation of norepinephrine uptake
F0051623biological_processpositive regulation of norepinephrine uptake
F0051726biological_processregulation of cell cycle
F0070062cellular_componentextracellular exosome
F0070160cellular_componenttight junction
F0070316biological_processregulation of G0 to G1 transition
F0070527biological_processplatelet aggregation
F0071564cellular_componentnpBAF complex
F0071565cellular_componentnBAF complex
F0071896biological_processprotein localization to adherens junction
F0072562cellular_componentblood microparticle
F0072749biological_processcellular response to cytochalasin B
F0097433cellular_componentdense body
F0098685cellular_componentSchaffer collateral - CA1 synapse
F0098793cellular_componentpresynapse
F0098871cellular_componentpostsynaptic actin cytoskeleton
F0098973molecular_functionstructural constituent of postsynaptic actin cytoskeleton
F0098974biological_processpostsynaptic actin cytoskeleton organization
F0098978cellular_componentglutamatergic synapse
F0140092cellular_componentbBAF complex
F0140288cellular_componentGBAF complex
F0150111biological_processregulation of transepithelial transport
F1900242biological_processregulation of synaptic vesicle endocytosis
F1902459biological_processpositive regulation of stem cell population maintenance
F1903076biological_processregulation of protein localization to plasma membrane
F1905168biological_processpositive regulation of double-strand break repair via homologous recombination
F1990904cellular_componentribonucleoprotein complex
F2000045biological_processregulation of G1/S transition of mitotic cell cycle
F2000779biological_processregulation of double-strand break repair
F2000781biological_processpositive regulation of double-strand break repair
F2000819biological_processregulation of nucleotide-excision repair
Functional Information from PROSITE/UniProt
site_idPS00019
Number of Residues10
DetailsACTININ_1 Actinin-type actin-binding domain signature 1. QKkTFTKWVN
ChainResidueDetails
fGLN1059-ASN1068

site_idPS00020
Number of Residues25
DetailsACTININ_2 Actinin-type actin-binding domain signature 2. LeNMGShDIvDgnhrLtLGLVWtII
ChainResidueDetails
fLEU1133-ILE1157

site_idPS00406
Number of Residues11
DetailsACTINS_1 Actins signature 1. YVGDEAQs.KRG
ChainResidueDetails
FTYR53-GLY63

site_idPS00432
Number of Residues9
DetailsACTINS_2 Actins signature 2. WISKqEYDE
ChainResidueDetails
FTRP356-GLU364

site_idPS01132
Number of Residues13
DetailsACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR
ChainResidueDetails
FLEU104-ARG116

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsMOD_RES: N-acetylserine => ECO:0007744|PubMed:20068231
ChainResidueDetails
fSER1002
aSER1002
bSER1002
cSER1002
dSER1002
eSER1002

site_idSWS_FT_FI2
Number of Residues6
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q9QWN8
ChainResidueDetails
fSER1006
aSER1006
bSER1006
cSER1006
dSER1006
eSER1006

site_idSWS_FT_FI3
Number of Residues6
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569
ChainResidueDetails
fSER1031
DMET47
EMET44
EMET47
aSER1031
bSER1031
cSER1031
dSER1031
eSER1031
CMET44
CMET47
DMET44

site_idSWS_FT_FI4
Number of Residues6
DetailsMOD_RES: Tele-methylhistidine => ECO:0000269|PubMed:30526847, ECO:0000269|PubMed:30626964, ECO:0000269|PubMed:30785395, ECO:0000269|PubMed:31388018, ECO:0000269|PubMed:32503840
ChainResidueDetails
FHIS73
AHIS73
BHIS73
CHIS73
DHIS73
EHIS73

site_idSWS_FT_FI5
Number of Residues6
DetailsMOD_RES: N6-methyllysine => ECO:0000269|PubMed:23673617
ChainResidueDetails
FLYS84
ALYS84
BLYS84
CLYS84
DLYS84
ELYS84

site_idSWS_FT_FI6
Number of Residues6
DetailsCROSSLNK: (Microbial infection) Isoglutamyl lysine isopeptide (Lys-Glu) (interchain with E-270); by Vibrio toxins RtxA and VgrG1 => ECO:0000305|PubMed:19015515
ChainResidueDetails
FLYS50
ALYS50
BLYS50
CLYS50
DLYS50
ELYS50

site_idSWS_FT_FI7
Number of Residues12
DetailsCROSSLNK: (Microbial infection) Isoglutamyl lysine isopeptide (Glu-Lys) (interchain with K-50); by Vibrio toxins RtxA and VgrG1 => ECO:0000305|PubMed:19015515
ChainResidueDetails
DGLU270
EGLU270
FGLU270
AGLU270
BGLU270
CGLU270

224201

PDB entries from 2024-08-28

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