PDB: 1811 件ウェブページステータス検索Chemie searchBIRD

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4OH5	Crystal structure of T877A-AR-LBD bound with co-regulator peptide 分子名称: Androgen receptor, HYDROXYFLUTAMIDE, SULFATE ION, ... 著者 Liu, J.S, Hsu, C.L, Wu, W.G. 登録日 2014-01-17 公開日 2014-08-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
4OHA	Crystal structure of T877A-AR-LBD bound with co-regulator peptide 分子名称: Androgen receptor, HYDROXYFLUTAMIDE, SULFATE ION, ... 著者 Liu, J.S, Hsu, C.L, Wu, W.G. 登録日 2014-01-17 公開日 2014-08-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
4OJ9	Crystal structure of T877A-AR-LBD bound with co-regulator peptide 分子名称: Androgen receptor, GLYCEROL, HYDROXYFLUTAMIDE, ... 著者 Liu, J.S, Hsu, C.L, Wu, W.G. 登録日 2014-01-20 公開日 2014-08-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
4OGH	Crystal structure of T877A-AR-LBD 分子名称: Androgen receptor, HYDROXYFLUTAMIDE, SULFATE ION 著者 Liu, J.S, Hsu, C.L, Wu, W.G. 登録日 2014-01-16 公開日 2014-08-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
4ONI	Structure of Human Orphan Receptor LRH1 bound to two bacterial phospholipids 分子名称: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, GLYCEROL, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, ... 著者 Gorman, M.A, Parker, M.W, Kusumo, S. 登録日 2014-01-28 公開日 2015-02-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Human nuclear receptor LRH1 bound to phosopholipids and SHP peptide To be Published
4OEY	Crystal structure of AR-LBD bound with co-regulator peptide 分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, SULFATE ION, ... 著者 Liu, J.S, Hsu, C.L, Wu, W.G. 登録日 2014-01-14 公開日 2014-08-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
4OH6	Crystal structure of T877A-AR-LBD bound with co-regulator peptide 分子名称: Androgen receptor, HYDROXYFLUTAMIDE, Protein BUD31 homolog, ... 著者 Liu, J.S, Hsu, C.L, Wu, W.G. 登録日 2014-01-17 公開日 2014-08-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.56 Å) 主引用文献 Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
4OKB	Crystal structure of W741L-AR-LBD bound with co-regulator peptide 分子名称: Androgen receptor, Protein BUD31 homolog, R-BICALUTAMIDE, ... 著者 Liu, J.S, Hsu, C.L, Wu, W.G. 登録日 2014-01-22 公開日 2014-08-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
4P6X	Crystal Structure of cortisol-bound glucocorticoid receptor ligand binding domain 分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, Glucocorticoid receptor, Nuclear receptor coactivator 2 著者 He, Y, Zhou, X.E, Tolbert, W.D, Powell, K, Melcher, K, Xu, H.E. 登録日 2014-03-25 公開日 2014-04-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures and mechanism for the design of highly potent glucocorticoids. Cell Res., 24, 2014
4P6W	Crystal Structure of mometasone furoate-bound glucocorticoid receptor ligand binding domain 分子名称: Glucocorticoid receptor, MOMETASONE FUROATE, Nuclear receptor coactivator 2 著者 He, Y, Zhou, X.E, Tolbert, W.D, Powell, K, Melcher, K, Xu, H.E. 登録日 2014-03-25 公開日 2014-04-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.951 Å) 主引用文献 Structures and mechanism for the design of highly potent glucocorticoids. Cell Res., 24, 2014
4PP6	Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with Resveratrol 分子名称: Estrogen receptor, Nuclear receptor coactivator 2, RESVERATROL 著者 Nwachukwu, J.C, Srinivasan, S, Bruno, N.E, Parent, A.A, Hughes, T.S, Pollock, J.A, Gjyshi, O, Cavett, V, Nowak, J, Garcia-Ordonez, R.D, Houtman, R, Griffin, P.R, Kojetin, D.J, Katzenellenbogen, J.A, Conkright, M.D, Nettles, K.W. 登録日 2014-02-26 公開日 2014-05-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.201 Å) 主引用文献 Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network. Elife, 3, 2014
4NB6	Crystal structure of the ligand binding domain of RORC with T0901317 分子名称: N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, Nuclear receptor ROR-gamma 著者 Hymowitz, S.G, Boenig-de Leon, G. 登録日 2013-10-22 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structure-based design of substituted hexafluoroisopropanol-arylsulfonamides as modulators of RORc. Bioorg.Med.Chem.Lett., 23, 2013
4NIE	Crystal structure of the orphan nuclear receptor ROR(gamma)t ligand-binding domain in complex with small molecule ligand 分子名称: 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, N-(4-{[benzyl(propyl)amino]methyl}phenyl)-2-[4-(ethylsulfonyl)phenyl]acetamide, Nuclear receptor ROR-gamma, ... 著者 Ma, Y.L, Yang, L.Q. 登録日 2013-11-06 公開日 2013-12-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Discovery of Tertiary Amine and Indole Derivatives as Potent ROR gamma t Inverse Agonists. Acs Med.Chem.Lett., 5, 2014
4OEA	Crystal structure of AR-LBD 分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor 著者 Liu, J.S, Hsu, C.L, Wu, W.G. 登録日 2014-01-12 公開日 2014-08-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
4OFR	Crystal structure of AR-LBD bound with co-regulator peptide 分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, co-regulator peptide 著者 Liu, J.S, Hsu, C.L, Wu, W.G. 登録日 2014-01-15 公開日 2014-08-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
4OFU	Crystal structure of AR-LBD bound with co-regulator peptide 分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, co-regulator peptide 著者 Liu, J.S, Hsu, C.L, Wu, W.G. 登録日 2014-01-15 公開日 2014-08-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
4N5G	Crystal Structure of RXRa LBD complexed with a synthetic modulator K8012 分子名称: 5-(2-{(1Z)-5-fluoro-2-methyl-1-[4-(propan-2-yl)benzylidene]-1H-inden-3-yl}ethyl)-1H-tetrazole, Retinoic acid receptor RXR-alpha 著者 Aleshin, A.E, Su, Y, Zhang, X, Liddington, R.C. 登録日 2013-10-09 公開日 2014-05-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Sulindac-Derived RXR alpha Modulators Inhibit Cancer Cell Growth by Binding to a Novel Site. Chem.Biol., 21, 2014
4N1Y	Crystal Structure of the Pacific Oyster Estrogen Receptor Ligand Binding Domain 分子名称: Estrogen receptor 著者 Ortlund, E.O. 登録日 2013-10-04 公開日 2014-02-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.605 Å) 主引用文献 Vestigialization of an allosteric switch: genetic and structural mechanisms for the evolution of constitutive activity in a steroid hormone receptor. PLoS Genet, 10, 2014
4PWL	Crystal structure of the complex between PPARgamma-LBD and the S enantiomer of Mbx-102 (Metaglidasen) 分子名称: (2S)-(4-chlorophenyl)[3-(trifluoromethyl)phenoxy]ethanoic acid, Peroxisome proliferator-activated receptor gamma 著者 Pochetti, G, Montanari, R, Capelli, D, Loiodice, F, Laghezza, A, Lavecchia, A, Piemontese, L. 登録日 2014-03-20 公開日 2015-02-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 On the metabolically active form of metaglidasen: improved synthesis and investigation of its peculiar activity on peroxisome proliferator-activated receptors and skeletal muscles. Chemmedchem, 10, 2015
4Q13	Apo Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant with a glucocorticoid receptor-interacting protein 1 NR box II peptide 分子名称: Estrogen receptor, Glucocorticoid receptor-interacting protein 1 NR box II peptide 著者 Fanning, S.W, Panchamukhi, S, Greene, G.L. 登録日 2014-04-02 公開日 2015-04-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation. Elife, 5, 2016
4Q0A	Vitamin D Receptor complex with lithocholic acid 分子名称: (3beta,5beta,14beta,17alpha)-3-hydroxycholan-24-oic acid, Nuclear receptor coactivator 2, Vitamin D3 receptor A 著者 Belorusova, A, Rochel, N. 登録日 2014-04-01 公開日 2014-07-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into the molecular mechanism of vitamin d receptor activation by lithocholic Acid involving a new mode of ligand recognition. J.Med.Chem., 57, 2014
4PRG	0072 PARTIAL AGONIST PPAR GAMMA COCRYSTAL 分子名称: (+/-)(2S,5S)-3-(4-(4-CARBOXYPHENYL)BUTYL)-2-HEPTYL-4-OXO-5-THIAZOLIDINE, PROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA) 著者 Milburn, M.V. 登録日 1999-05-07 公開日 1999-05-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A peroxisome proliferator-activated receptor gamma ligand inhibits adipocyte differentiation. Proc.Natl.Acad.Sci.USA, 96, 1999
4PF3	Mineralocorticoid receptor ligand-binding domain with compuond 37a 分子名称: 1,2-ETHANEDIOL, 6-[1-(2,2-difluoro-3-hydroxypropyl)-5-(4-fluorophenyl)-3-methyl-1H-pyrazol-4-yl]-2H-1,4-benzoxazin-3(4H)-one, Mineralocorticoid receptor 著者 Sogabe, S, Habuka, N. 登録日 2014-04-28 公開日 2014-11-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Discovery of 6-[5-(4-fluorophenyl)-3-methyl-pyrazol-4-yl]-benzoxazin-3-one derivatives as novel selective nonsteroidal mineralocorticoid receptor antagonists Bioorg.Med.Chem., 22, 2014
4N73	Crystal structure of the ligand binding domain (LBD) of REV-ERB beta bound to Cobalt Protoporphyrin IX 分子名称: Nuclear receptor subfamily 1 group D member 2, PROTOPORPHYRIN IX CONTAINING CO 著者 Matta-Camacho, E, Kojetin, D. 登録日 2013-10-14 公開日 2014-06-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8662 Å) 主引用文献 Structure of REV-ERB beta Ligand-binding Domain Bound to a Porphyrin Antagonist. J.Biol.Chem., 289, 2014
4PXM	The Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant in Complex with Estradiol and a glucocorticoid receptor-interacting protein 1 NR box II peptide 分子名称: ESTRADIOL, Estrogen receptor, Nuclear receptor coactivator 2 著者 Fanning, S.W, Panchamukhi, S, Greene, G.L. 登録日 2014-03-24 公開日 2015-04-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation. Elife, 5, 2016

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