4OKB
Crystal structure of W741L-AR-LBD bound with co-regulator peptide
Summary for 4OKB
Entry DOI | 10.2210/pdb4okb/pdb |
Related | 4OEA 4OED 4OEY 4OEZ 4OFR 4OFU 4OGH 4OH5 4OH6 4OHA 4OIL 4OIU 4OJ9 4OJB 4OK1 4OKT 4OKW 4OKX 4OLM |
Descriptor | Androgen receptor, Protein BUD31 homolog, SULFATE ION, ... (5 entities in total) |
Functional Keywords | alpha-helix, hormone/growth factor receptor, phosphorylation, hormone receptor-peptide complex, signal transduction, hormone receptor/peptide |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P10275 P41223 |
Total number of polymer chains | 2 |
Total formula weight | 31558.87 |
Authors | |
Primary citation | Hsu, C.L.,Liu, J.S.,Wu, P.L.,Guan, H.H.,Chen, Y.L.,Lin, A.C.,Ting, H.J.,Pang, S.T.,Yeh, S.D.,Ma, W.L.,Chen, C.J.,Wu, W.G.,Chang, C. Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8:1575-1587, 2014 Cited by PubMed: 25091737DOI: 10.1016/j.molonc.2014.06.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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