4OGH

Crystal structure of T877A-AR-LBD

Summary for 4OGH

• Entry DOI: 10.2210/pdb4ogh/pdb
• Related: 4OEA 4OED 4OEY 4OEZ 4OFR 4OFU 4OH5 4OH6 4OHA 4OIL 4OIU 4OJ9 4OJB 4OK1 4OKB 4OKT 4OKW 4OKX 4OLM
• Descriptor: Androgen receptor, HYDROXYFLUTAMIDE, SULFATE ION, ... (4 entities in total)
• Functional Keywords: alpha helix, signal transduction, co-regulator, phosphorylation, hormone receptor
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P10275
• Total number of polymer chains: 1
• Total formula weight: 29446.33

Authors

Liu, J.S.,Hsu, C.L.,Wu, W.G. (deposition date: 2014-01-16, release date: 2014-08-20, Last modification date: 2023-09-20)

• Primary citation: Hsu, C.L.,Liu, J.S.,Wu, P.L.,Guan, H.H.,Chen, Y.L.,Lin, A.C.,Ting, H.J.,Pang, S.T.,Yeh, S.D.,Ma, W.L.,Chen, C.J.,Wu, W.G.,Chang, C.; Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.; Mol Oncol, 8:1575-1587, 2014; PubMed: 25091737; DOI: 10.1016/j.molonc.2014.06.009

Experimental method

X-RAY DIFFRACTION (2.98 Å)