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4OGH

Crystal structure of T877A-AR-LBD

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Androgen receptorpolymer25029058.11UniProt (P10275)
Pfam (PF00104)
Homo sapiens (human)Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
2B
(A)
HYDROXYFLUTAMIDEnon-polymer292.21Chemie (HFT)
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D
(A)
waterwater18.09Chemie (HOH)
Sequence modifications
A: 670 - 919 (UniProt: P10275)
PDBExternal DatabaseDetails
Ala 760Arg 760engineered mutation
Ala 877Thr 877engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29058.1
Non-Polymers*Number of molecules2
Total formula weight388.3
All*Total formula weight29446.3
*Water molecules are not included.

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PDB entries from 2025-12-03

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