6LPX
 
 | | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with 2-oxoglutarate (2-OG) | | 分子名称: | 2-OXOGLUTARIC ACID, D-2-hydroxyglutarate dehydrogenase, mitochondrial, ... | | 著者 | Yang, J, Zhu, H, Ding, J. | | 登録日 | 2020-01-12 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations.
Cell Discov, 7, 2021
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7YNR
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7YNL
 | | EB-bound alpha-synuclein fibrils | | 分子名称: | 4-azanyl-6-[[4-[4-[(~{E})-(8-azanyl-1-oxidanyl-5,7-disulfo-naphthalen-2-yl)diazenyl]-3-methyl-phenyl]-2-methyl-phenyl]diazenyl]-5-oxidanyl-naphthalene-1,3-disulfonic acid, Alpha-synuclein | | 著者 | Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. | | 登録日 | 2022-07-31 | | 公開日 | 2023-08-02 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | EB-bound alpha-synuclein fibrils
To Be Published
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4G5F
 | | Pantothenate synthetase in complex with racemate (2S)-2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBOXYLIC ACID and (2R)-2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBOXYLIC ACID | | 分子名称: | (2R)-2,3-dihydro-1,4-benzodioxine-2-carboxylic acid, (2S)-2,3-dihydro-1,4-benzodioxine-2-carboxylic acid, 1,2-ETHANEDIOL, ... | | 著者 | Silvestre, H.L, Blundell, T.L, Abell, C, Ciulli, A. | | 登録日 | 2012-07-17 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Integrated biophysical approach to fragment screening and validation for fragment-based lead discovery.
Proc.Natl.Acad.Sci.USA, 110, 2013
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6LQJ
 | | Low resolution architecture of curli complex | | 分子名称: | Curli production assembly/transport component CsgF, Curli production assembly/transport component CsgG | | 著者 | Zhang, M, Shi, H, Huang, Y. | | 登録日 | 2020-01-13 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | Cryo-EM structure of the nonameric CsgG-CsgF complex and its implications for controlling curli biogenesis in Enterobacteriaceae.
Plos Biol., 18, 2020
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2G7J
 | | Solution NMR structure of the putative cytoplasmic protein ygaC from Salmonella typhimurium. Northeast Structural Genomics target StR72. | | 分子名称: | putative cytoplasmic protein | | 著者 | Aramini, J.M, Swapna, G.V.T, Ramelot, T.A, Ho, C.K, Cunningham, K, Ma, L.-C, Shetty, K, Xiao, R, Acton, T.B, Kennedy, M.A, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2006-02-28 | | 公開日 | 2006-05-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of the putative cytoplasmic protein ygaC from Salmonella typhimurium. Northeast Structural Genomics target StR72.
To be Published
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7YNP
 | | BF227-bound alpha-synuclein fibrils | | 分子名称: | 5-[(~{E})-2-(6-methoxy-1,3-benzoxazol-2-yl)ethenyl]-~{N},~{N}-dimethyl-1,3-thiazol-2-amine, Alpha-synuclein | | 著者 | Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. | | 登録日 | 2022-07-31 | | 公開日 | 2023-08-02 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | BF227-bound alpha-synuclein fibrils
To Be Published
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4G76
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7D88
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5I6U
 | | The crystal structure of PI3Kdelta with compound 32 | | 分子名称: | 2-[(1S)-1-({6-amino-5-[(1H-pyrazol-4-yl)ethynyl]pyrimidin-4-yl}amino)ethyl]-5-chloro-3-phenylquinazolin-4(3H)-one, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | | 著者 | Somoza, J.R, Villasenor, A.G. | | 登録日 | 2016-02-16 | | 公開日 | 2017-02-22 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.842 Å) | | 主引用文献 | The crystal structure of PI3Kdelta with compound 32
To Be Published
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7DB6
 | | human melatonin receptor MT1 - Gi1 complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Okamoto, H.H, Kusakizako, T, Shihioya, W, Yamashita, K, Nishizawa, T, Nureki, O. | | 登録日 | 2020-10-19 | | 公開日 | 2021-08-18 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structure of the human MT 1 -G i signaling complex.
Nat.Struct.Mol.Biol., 28, 2021
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7YNN
 | | ThT-bound alpha-synuclein fibrils conformation 2 | | 分子名称: | 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, Alpha-synuclein | | 著者 | Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. | | 登録日 | 2022-07-31 | | 公開日 | 2023-08-02 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | ThT-bound alpha-synuclein fibrils conformation 2
To Be Published
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7D1L
 | | complex structure of two RRM domains | | 分子名称: | Embryonic developmental protein tofu-6, Uncharacterized protein | | 著者 | Wang, X, Liao, S, Xu, C. | | 登録日 | 2020-09-14 | | 公開日 | 2021-08-25 | | 最終更新日 | 2021-10-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Molecular basis for PICS-mediated piRNA biogenesis and cell division.
Nat Commun, 12, 2021
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7D89
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7D2Y
 | | complex of two RRM domains | | 分子名称: | Embryonic developmental protein tofu-6, RRM2, SULFATE ION | | 著者 | Wang, X, Liao, S, Xu, C. | | 登録日 | 2020-09-17 | | 公開日 | 2021-08-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Molecular basis for PICS-mediated piRNA biogenesis and cell division.
Nat Commun, 12, 2021
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2G96
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7YNO
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4GA5
 | | Crystal structure of AMP phosphorylase C-terminal deletion mutant in the apo-form | | 分子名称: | Putative thymidine phosphorylase | | 著者 | Nishitani, Y, Aono, R, Nakamura, A, Sato, T, Atomi, H, Imanaka, T, Miki, K. | | 登録日 | 2012-07-25 | | 公開日 | 2013-05-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structure analysis of archaeal AMP phosphorylase reveals two unique modes of dimerization
J.Mol.Biol., 425, 2013
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6LT8
 | | HSP90 in complex with KW-2478 | | 分子名称: | 2-[2-ethyl-6-[3-methoxy-4-(2-morpholin-4-ylethoxy)phenyl]carbonyl-3,5-bis(oxidanyl)phenyl]-~{N},~{N}-bis(2-methoxyethyl)ethanamide, Heat shock protein HSP 90-alpha | | 著者 | Cao, H.L. | | 登録日 | 2020-01-21 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.593 Å) | | 主引用文献 | Anti-NSCLC activity in vitro of Hsp90 N inhibitor KW-2478 and complex crystal structure determination of Hsp90 N -KW-2478.
J.Struct.Biol., 213, 2021
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6LKD
 | | in meso full-length rat KMO in complex with a pyrazoyl benzoic acid inhibitor | | 分子名称: | 5-[5-(4-chloranyl-3-fluoranyl-phenyl)-4-methyl-pyrazol-1-yl]-2-phenylmethoxy-benzoic acid, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Mimasu, S, Yamagishi, H, Kiyohara, M, Kakefuda, K, Okuda, T. | | 登録日 | 2019-12-19 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Full-length in meso structure and mechanism of rat kynurenine 3-monooxygenase inhibition.
Commun Biol, 4, 2021
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7YNG
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7YNS
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5IML
 | | Nanobody targeting human Vsig4 in Spacegroup P212121 | | 分子名称: | Nanobody, V-set and immunoglobulin domain-containing protein 4 | | 著者 | Wen, Y. | | 登録日 | 2016-03-06 | | 公開日 | 2017-01-11 | | 最終更新日 | 2017-07-05 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity
Immunobiology, 222, 2017
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4EHT
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7YQS
 | | Neutron structure of a L-rhamnose-alpha-1,4-D-glucuronate lyase from Fusarium oxysporum 12S, L-Rha complex | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CALCIUM ION, ... | | 著者 | Yano, N, Kondo, T, Kusaka, K, Yamada, T, Arakawa, T, Sakamoto, T, Fushinobu, S. | | 登録日 | 2022-08-08 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-03-27 | | 実験手法 | NEUTRON DIFFRACTION (1.25 Å), X-RAY DIFFRACTION | | 主引用文献 | Charge neutralization and beta-elimination cleavage mechanism of family 42 L-rhamnose-alpha-1,4-D-glucuronate lyase revealed using neutron crystallography.
J.Biol.Chem., 300, 2024
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