5I6U
The crystal structure of PI3Kdelta with compound 32
Summary for 5I6U
Entry DOI | 10.2210/pdb5i6u/pdb |
Related | 5I4U |
Descriptor | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, 2-[(1S)-1-({6-amino-5-[(1H-pyrazol-4-yl)ethynyl]pyrimidin-4-yl}amino)ethyl]-5-chloro-3-phenylquinazolin-4(3H)-one (2 entities in total) |
Functional Keywords | kinase, p110, kinase inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Mus musculus (Mouse) |
Cellular location | Cytoplasm : O35904 |
Total number of polymer chains | 1 |
Total formula weight | 108249.53 |
Authors | Somoza, J.R.,Villasenor, A.G. (deposition date: 2016-02-16, release date: 2017-02-22, Last modification date: 2023-09-27) |
Primary citation | Somoza, J.R.,Villasenor, A.G. The crystal structure of PI3Kdelta with compound 32 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.842 Å) |
Structure validation
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