6LKD

in meso full-length rat KMO in complex with a pyrazoyl benzoic acid inhibitor

Summary for 6LKD

Entry DOI	10.2210/pdb6lkd/pdb
Descriptor	Kynurenine 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, 5-[5-(4-chloranyl-3-fluoranyl-phenyl)-4-methyl-pyrazol-1-yl]-2-phenylmethoxy-benzoic acid, ... (6 entities in total)
Functional Keywords	single pass transmembrane, kmo, hydroxygenase, flavoprotein, membrane protein
Biological source	Rattus norvegicus (Rat)
Total number of polymer chains	2
Total formula weight	115546.32
Authors	Mimasu, S.,Yamagishi, H.,Kiyohara, M.,Kakefuda, K.,Okuda, T. (deposition date: 2019-12-19, release date: 2020-12-23, Last modification date: 2023-11-22)
Primary citation	Mimasu, S.,Yamagishi, H.,Kubo, S.,Kiyohara, M.,Matsuda, T.,Yahata, T.,Thomson, H.A.,Hupp, C.D.,Liu, J.,Okuda, T.,Kakefuda, K. Full-length in meso structure and mechanism of rat kynurenine 3-monooxygenase inhibition. Commun Biol, 4:159-159, 2021 Cited by PubMed: 33542467 DOI: 10.1038/s42003-021-01666-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation