6LKD

in meso full-length rat KMO in complex with a pyrazoyl benzoic acid inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Kynurenine 3-monooxygenase	polymer	495	56419.2	2	UniProt (O88867) Pfam (PF01494) In PDB	Rattus norvegicus (Rat)	Kynurenine 3-hydroxylase
2	A, B	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	2	Chemie (FAD)
3	A, B	5-[5-(4-chloranyl-3-fluoranyl-phenyl)-4-methyl-pyrazol-1-yl]-2-phenylmethoxy-benzoic acid	non-polymer		436.9	2	Chemie (EGO)
4	A, B	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5	A, B	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
6		water	water		18.0	6	Chemie (HOH)

Sequence modifications

A, B: 1 - 478 (UniProt: O88867)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag
Glu 479	-	expression tag
Asn 480	-	expression tag
Leu 481	-	expression tag
Tyr 482	-	expression tag
Phe 483	-	expression tag
Gln 484	-	expression tag
Gly 485	-	expression tag
Asp 486	-	expression tag
Tyr 487	-	expression tag
Lys 488	-	expression tag
Asp 489	-	expression tag
Asp 490	-	expression tag
Asp 491	-	expression tag
Asp 492	-	expression tag
Lys 493	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	112838.5
Non-Polymers*	Number of molecules	8
	Total formula weight	2707.9
All*	Total formula weight	115546.3

*Water molecules are not included.