PDB: 30805 件ウェブページステータス検索Chemie searchBIRD

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6AI4	Structure of Transferase mutant-C21S,C199S 分子名称: Non-LEE encoded effector protein NleB 著者 Park, J.B, Yoo, Y, Kim, J. 登録日 2018-08-21 公開日 2018-10-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Transferase mutant-C21S,C199S To Be Published
5AO7	Crystal Structure of SltB3 from Pseudomonas aeruginosa in complex with NAG-anhNAM-pentapeptide 分子名称: 2-(2-ACETYLAMINO-4-HYDROXY-6,8-DIOXA-BICYCLO[3.2.1]OCT-3-YLOXY)-PROPIONIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Dominguez-Gil, T, Hermoso, J.A. 登録日 2015-09-09 公開日 2016-07-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Turnover of Bacterial Cell Wall by Sltb3, a Multidomain Lytic Transglycosylase of Pseudomonas Aeruginosa. Acs Chem.Biol., 11, 2016
7MY1	Sy-CrtE structure with IPP, N-term His-tag 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, CHLORIDE ION, Geranylgeranyl pyrophosphate synthase, ... 著者 Peat, T.S, Newman, J. 登録日 2021-05-19 公開日 2022-06-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase. Febs J., 289, 2022
6A16	Crystal structure of CYP90B1 in complex with uniconazole 分子名称: (1E,3S)-1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol, CHLORIDE ION, Cytochrome P450 90B1, ... 著者 Fujiyama, K, Hino, T, Kanadani, M, Mizutani, M, Nagano, S. 登録日 2018-06-06 公開日 2019-06-12 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.998 Å) 主引用文献 Structural insights into a key step of brassinosteroid biosynthesis and its inhibition. Nat.Plants, 5, 2019
6OHM	Structure of tungstate bound human Phospholipase D2 catalytic domain 分子名称: GLYCEROL, Phospholipase D2, SULFATE ION, ... 著者 Metrick, C.M, Chodaparambil, J.V. 登録日 2019-04-06 公開日 2020-02-19 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.895 Å) 主引用文献 Human PLD structures enable drug design and characterization of isoenzyme selectivity. Nat.Chem.Biol., 16, 2020
5AOH	Crystal Structure of CarF 分子名称: POTASSIUM ION, Spore coat protein CotH 著者 Tichy, E.M, Hardwick, S.W, Luisi, B.F, C Salmond, G.P. 登録日 2015-09-10 公開日 2017-01-25 最終更新日 2019-09-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 1.8 angstrom resolution crystal structure of the carbapenem intrinsic resistance protein CarF. Acta Crystallogr D Struct Biol, 73, 2017
7MXZ	Sy-CrtE apo structure 分子名称: CHLORIDE ION, Geranylgeranyl pyrophosphate synthase, MAGNESIUM ION 著者 Peat, T.S, Newman, J. 登録日 2021-05-19 公開日 2022-06-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase. Febs J., 289, 2022
6U8I	BRD4-BD2 in complex with the cyclic peptide 3.2_2 分子名称: AMINO GROUP, Bromodomain-containing protein 4, cyclic peptide 3.2_2 著者 Patel, K, Walshe, J.L, Walport, L.J, Mackay, J.P. 登録日 2019-09-05 公開日 2020-08-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Cyclic peptides can engage a single binding pocket through highly divergent modes. Proc.Natl.Acad.Sci.USA, 117, 2020
7TE0	Structure of the SARS-CoV-2 main protease in complex with inhibitor PF-07321332 分子名称: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase 著者 Yang, K.S, Liu, W.R. 登録日 2022-01-03 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Evolutionary and Structural Insights about Potential SARS-CoV-2 Evasion of Nirmatrelvir. J.Med.Chem., 65, 2022
8COX	Mycobacterium tuberculosis dihydrofolate reductase in complex with N-(2-(2,6-diamino-5-(cyclopropylethynyl)pyrimidin-4-yl)phenyl)methanesulfonamide 分子名称: COBALT (II) ION, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Kirkman, T.J, Dias, M.V.B, Coyne, A.G. 登録日 2023-03-01 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Currently unpublished To Be Published
8P9M	Hexameric Hfq from Chromobacterium haemolyticum 分子名称: GLYCEROL, RNA-binding protein Hfq 著者 Nikulin, A.D, Lekontseva, N.V. 登録日 2023-06-06 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Structure of the Hfq Protein from Chromobacterium haemolyticum Revealed a New Variant of Regulation of RNA Binding with the Protein Crystallography Reports, 68, 2023
7MY7	Se-CrtE N-term His-tag structure 分子名称: Farnesyl-diphosphate synthase 著者 Peat, T.S, Newman, J. 登録日 2021-05-20 公開日 2022-06-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase. Febs J., 289, 2022
7MYL	Crystal structure of DfrA1 dihydrofolate reductase in complex with TRIMETHOPRIM 分子名称: Dihydrofolate reductase, TRIMETHOPRIM 著者 Erlandsen, H, Wright, D. 登録日 2021-05-21 公開日 2022-06-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structure-guided functional studies of plasmid-encoded dihydrofolate reductases reveal a common mechanism of trimethoprim resistance in Gram-negative pathogens. Commun Biol, 5, 2022
8C6N	Human protein kinase CK2 alpha in complex with CK2-TN03 分子名称: (2~{Z},5~{Z})-5-[(4-methoxy-3-oxidanyl-phenyl)methylidene]-2-phenylimino-1,3-thiazolidin-4-one, Casein kinase II subunit alpha, SULFATE ION 著者 Dalle Vedove, A, Cazzanelli, G, Lolli, G. 登録日 2023-01-12 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Switching off CK2-mediated activation of survivin offers new therapeutic opportunities in neuroblastoma to be published
8OYZ	Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK10 分子名称: 2-azanyl-7,8-dihydro-6~{H}-quinazolin-5-one, Chemotaxis protein CheA 著者 Adhav, A, Marina, A. 登録日 2023-05-05 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK10 To Be Published
5B2T	Crystal structure of the Streptococcus pyogenes Cas9 VRER variant in complex with sgRNA and target DNA (TGCG PAM) 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CRISPR-associated endonuclease Cas9, ... 著者 Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2016-02-02 公開日 2016-03-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9 Mol.Cell, 61, 2016
8COW	Mycobacterium tuberculosis dihydrofolate reductase in complex with 5-(cyclopropylethynyl)-6-(2-fluorophenyl)pyrimidine-2,4-diamine 分子名称: 5-(2-cyclopropylethynyl)-6-(2-fluorophenyl)pyrimidine-2,4-diamine, COBALT (II) ION, Dihydrofolate reductase, ... 著者 Kirkman, T.J, Dias, M.V.B, Coyne, A.G. 登録日 2023-03-01 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Currently unpublished To Be Published
7T36	Crystal structure of the tandem bromodomain (BD1 and BD2) of human TAF1 bound to ZS1-322 分子名称: (3R)-4-[6-{1-[diamino(hydroxy)-lambda~4~-sulfanyl]cyclopropyl}-2-(methylsulfanyl)pyrimidin-4-yl]-3-methylmorpholine, 1,2-ETHANEDIOL, Transcription initiation factor TFIID subunit 1 著者 Karim, M.R, Schonbrunn, E. 登録日 2021-12-07 公開日 2022-01-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of the tandem bromodomain (BD1 and BD2) of human TAF1 bound to ZS1-322 To Be Published
8OZ9	Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound QUI-SV-383 分子名称: 7-(1~{H}-1,2,3-triazol-5-yl)quinazolin-2-amine, Chemotaxis protein CheA 著者 Adhav, A, Marina, A. 登録日 2023-05-08 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound QUI-SV-383 To Be Published
7VR6	Crystal structure of MlaC from Escherichia coli in quasi-open state 分子名称: 1,2-ETHANEDIOL, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, Intermembrane phospholipid transport system binding protein MlaC 著者 Dutta, A, Kanaujia, S.P. 登録日 2021-10-21 公開日 2022-09-21 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 MlaC belongs to a unique class of non-canonical substrate-binding proteins and follows a novel phospholipid-binding mechanism. J.Struct.Biol., 214, 2022
8C6M	Human protein kinase CK2 alpha in complex with CK2-TN02 分子名称: (5~{Z})-5-[(3-methoxy-4-oxidanyl-phenyl)methylidene]-1,3-thiazolidine-2,4-dione, Casein kinase II subunit alpha, SULFATE ION 著者 Dalle Vedove, A, Cazzanelli, G, Lolli, G. 登録日 2023-01-12 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Switching off CK2-mediated activation of survivin offers new therapeutic opportunities in neuroblastoma to be published
6UNW	Epoxide hydrolase from an endophytic Streptomyces 分子名称: CACODYLATE ION, CHLORIDE ION, Soluble epoxide hydrolase 著者 Wilson, C, dos Santos, J.C, Dias, M.V.B. 登録日 2019-10-13 公開日 2020-09-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 An epoxide hydrolase from endophytic Streptomyces shows unique structural features and wide biocatalytic activity. Acta Crystallogr D Struct Biol, 76, 2020
8CPQ	Crystal structure of human protein disulfide isomerase PDIA6 domain b 分子名称: Protein disulfide-isomerase A6 著者 Jakob, R.P, Leder, A.L, Hiller, S, Maier, T. 登録日 2023-03-03 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of human protein disulfide isomerase PDIA6 domain b To Be Published
6A35	Crystal structure of 5-methylthioribose 1-phosphate isomerase from Pyrococcus horikoshii OT3 - Form II 分子名称: Putative methylthioribose-1-phosphate isomerase 著者 Kanaujia, S.P, Gogoi, P, Mordina, P. 登録日 2018-06-14 公開日 2018-12-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural insights into the catalytic mechanism of 5-methylthioribose 1-phosphate isomerase. J. Struct. Biol., 205, 2019
6OJA	Crystal structure of the N. meningitides methionine-binding protein in its L-methionine bound conformation 分子名称: Lipoprotein, METHIONINE 著者 Nguyen, P.T, Lai, J.Y, Kaiser, J.T, Rees, D.C. 登録日 2019-04-11 公開日 2019-08-07 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structures of the Neisseria meningitides methionine-binding protein MetQ in substrate-free form and bound to l- and d-methionine isomers. Protein Sci., 28, 2019

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