8COX

Mycobacterium tuberculosis dihydrofolate reductase in complex with N-(2-(2,6-diamino-5-(cyclopropylethynyl)pyrimidin-4-yl)phenyl)methanesulfonamide

Summary for 8COX

• Entry DOI: 10.2210/pdb8cox/pdb
• Descriptor: Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PHOSPHATE ION, ... (6 entities in total)
• Functional Keywords: mycobacterium tuberculosis dihydrofolate reductase, biosynthetic protein
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 2
• Total formula weight: 38023.61

Authors

Kirkman, T.J.,Dias, M.V.B.,Coyne, A.G. (deposition date: 2023-03-01, release date: 2024-03-13, Last modification date: 2025-10-01)

• Primary citation: Kirkman, T.J.,Dias, M.V.B.; Currently unpublished; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)