3MH2
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![BU of 3mh2 by Molmil](/molmil-images/mine/3mh2) | Mutagenesis of p38 MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-out state | 分子名称: | Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | 著者 | Namboodiri, H.V, Karpusas, M, Bukhtiyarova, M, Springman, E.B. | 登録日 | 2010-04-07 | 公開日 | 2010-04-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mutagenesis of p38alpha MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-OUT state. Biochemistry, 46, 2007
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7CXD
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6S0Z
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![BU of 6s0z by Molmil](/molmil-images/mine/6s0z) | Erythromycin Resistant Staphylococcus aureus 50S ribosome (delta R88 A89 uL22) in complex with erythromycin. | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Halfon, Y, Matozv, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H, Yonath, A. | 登録日 | 2019-06-18 | 公開日 | 2019-08-21 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant. Sci Rep, 9, 2019
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5IOU
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![BU of 5iou by Molmil](/molmil-images/mine/5iou) | Cryo-EM structure of GluN1/GluN2B NMDA receptor in the glutamate/glycine-bound conformation | 分子名称: | GLUTAMIC ACID, GLYCINE, Ionotropic glutamate receptor subunit NR2B, ... | 著者 | Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E. | 登録日 | 2016-03-09 | 公開日 | 2016-04-20 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Mechanism of NMDA Receptor Inhibition and Activation. Cell, 165, 2016
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5IPU
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![BU of 5ipu by Molmil](/molmil-images/mine/5ipu) | Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 6 | 分子名称: | Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a | 著者 | Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E. | 登録日 | 2016-03-09 | 公開日 | 2016-04-20 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (15.4 Å) | 主引用文献 | Mechanism of NMDA Receptor Inhibition and Activation. Cell, 165, 2016
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7CYY
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![BU of 7cyy by Molmil](/molmil-images/mine/7cyy) | Crystal structure of Arabinose isomerase from hybrid AI8 with Adonitol | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, D-ribitol, L-arabinose isomerase, ... | 著者 | Hoang, N.K.Q, Dhanasingh, I, Cao, T.P, Sung, J.Y, Shin, S.M, Lee, D.W, Lee, S.H. | 登録日 | 2020-09-05 | 公開日 | 2021-09-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of Arabinose isomerase from hyper thermophilic hybrid AI8 with Adonitol To Be Published
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7CZJ
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3MMC
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![BU of 3mmc by Molmil](/molmil-images/mine/3mmc) | Structure of the dissimilatory sulfite reductase from Archaeoglobus fulgidus | 分子名称: | GLYCEROL, IRON/SULFUR CLUSTER, SIROHEME, ... | 著者 | Schiffer, A, Parey, K, Warkentin, E, Diederichs, K, Huber, H, Stetter, K.O, Kroneck, P.M.H, Ermler, U. | 登録日 | 2010-04-19 | 公開日 | 2010-05-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Structure of the dissimilatory sulfite reductase from the hyperthermophilic archaeon Archaeoglobus fulgidus. J.Mol.Biol., 379, 2008
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7CXO
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![BU of 7cxo by Molmil](/molmil-images/mine/7cxo) | Crystal structure of Arabinose isomerase from hybrid AI10 | 分子名称: | GLYCEROL, L-arabinose isomerase, MANGANESE (II) ION | 著者 | Hoang, N.K.Q, Dhanasingh, I, Cao, T.P, Sung, J.Y, Shin, S.M, Lee, D.W, Lee, S.H. | 登録日 | 2020-09-02 | 公開日 | 2021-09-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of Arabinose isomerase from hyper thermophilic hybrid AI10 To Be Published
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7DRP
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![BU of 7drp by Molmil](/molmil-images/mine/7drp) | Structure of ATP-grasp ligase PsnB complexed with phosphomimetic variant of minimal precursor, Mg, and ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-grasp domain-containing protein, MAGNESIUM ION, ... | 著者 | Song, I, Yu, J, Song, W, Kim, S. | 登録日 | 2020-12-29 | 公開日 | 2021-09-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Molecular mechanism underlying substrate recognition of the peptide macrocyclase PsnB. Nat.Chem.Biol., 17, 2021
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7CZC
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![BU of 7czc by Molmil](/molmil-images/mine/7czc) | Crystal structure of apo-FabG from Vibrio harveyi | 分子名称: | 3-oxoacyl-ACP reductase FabG, DI(HYDROXYETHYL)ETHER | 著者 | Singh, B.K, Kumar, A, Paul, B, Biswas, R, Das, A.K. | 登録日 | 2020-09-08 | 公開日 | 2021-09-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of apo-FabG from Vibrio harveyi To Be Published
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7DRO
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![BU of 7dro by Molmil](/molmil-images/mine/7dro) | Structure of ATP-grasp ligase PsnB complexed with minimal precursor | 分子名称: | ATP-grasp domain-containing protein, PsnA214-38, Precursor peptide | 著者 | Song, I, Yu, J, Song, W, Kim, S. | 登録日 | 2020-12-29 | 公開日 | 2021-09-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Molecular mechanism underlying substrate recognition of the peptide macrocyclase PsnB. Nat.Chem.Biol., 17, 2021
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7DRM
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![BU of 7drm by Molmil](/molmil-images/mine/7drm) | Structure of ATP-grasp ligase PsnB complexed with minimal precursor, Mg, and ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-grasp domain-containing protein, MAGNESIUM ION, ... | 著者 | Song, I, Yu, J, Song, W, Kim, S. | 登録日 | 2020-12-29 | 公開日 | 2021-09-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.28 Å) | 主引用文献 | Molecular mechanism underlying substrate recognition of the peptide macrocyclase PsnB. Nat.Chem.Biol., 17, 2021
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3MRY
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![BU of 3mry by Molmil](/molmil-images/mine/3mry) | Crystal Structure of type I ribosome inactivating protein from Momordica balsamina with 6-aminopurine at 2.0A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, GLYCEROL, ... | 著者 | Kushwaha, G.S, Pandey, N, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2010-04-29 | 公開日 | 2010-06-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of type I ribosome inactivating protein from Momordica balsamina with 6-aminopurine at 2.0A resolution To be Published
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7DRN
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![BU of 7drn by Molmil](/molmil-images/mine/7drn) | Structure of ATP-grasp ligase PsnB complexed with precursor peptide PsnA2 and AMPPNP | 分子名称: | ATP-grasp domain-containing protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PsnA214-38, ... | 著者 | Song, I, Yu, J, Song, W, Kim, S. | 登録日 | 2020-12-29 | 公開日 | 2021-09-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.56 Å) | 主引用文献 | Molecular mechanism underlying substrate recognition of the peptide macrocyclase PsnB. Nat.Chem.Biol., 17, 2021
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6RHZ
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![BU of 6rhz by Molmil](/molmil-images/mine/6rhz) | Structure of a minimal photosystem I from a green alga | 分子名称: | (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... | 著者 | Perez Boerema, A, Klaiman, D, Caspy, I, Netzer-El, S.Y, Amunts, A, Nelson, N. | 登録日 | 2019-04-23 | 公開日 | 2020-02-19 | 最終更新日 | 2020-03-25 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of a minimal photosystem I from the green alga Dunaliella salina. Nat.Plants, 6, 2020
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7DDX
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![BU of 7ddx by Molmil](/molmil-images/mine/7ddx) | Crystal structure of KANK1 S1179F mutant in complex wtih eIF4A1 | 分子名称: | Eukaryotic initiation factor 4A-I, GLYCEROL, KN motif and ankyrin repeat domains 1, ... | 著者 | Pan, W, Xu, Y, Wei, Z. | 登録日 | 2020-10-30 | 公開日 | 2021-09-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Nephrotic-syndrome-associated mutation of KANK2 induces pathologic binding competition with physiological interactor KIF21A. J.Biol.Chem., 297, 2021
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7DAJ
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![BU of 7daj by Molmil](/molmil-images/mine/7daj) | The crystal structure of serotonin N-acetyltransferase in complex with acetyl-CoA from Oryza Sativa | 分子名称: | ACETYL COENZYME *A, Serotonin N-acetyltransferase 1, chloroplastic | 著者 | Zhou, Y.Z, Liao, L.J, Tang, T, Guo, Y, Liu, X.K, Liu, B, Zhao, Y.C. | 登録日 | 2020-10-16 | 公開日 | 2021-09-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and Molecular Dynamics Analysis of Plant Serotonin N-Acetyltransferase Reveal an Acid/Base-Assisted Catalysis in Melatonin Biosynthesis. Angew.Chem.Int.Ed.Engl., 60, 2021
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7D2F
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![BU of 7d2f by Molmil](/molmil-images/mine/7d2f) | Lp major histidine acid phosphatase mutant D281A/5'-AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, Major acid phosphatase | 著者 | Guo, Y, Teng, Y. | 登録日 | 2020-09-16 | 公開日 | 2021-09-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural insights into a new substrate binding mode of a histidine acid phosphatase from Legionella pneumophila. Biochem.Biophys.Res.Commun., 540, 2021
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7CYI
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![BU of 7cyi by Molmil](/molmil-images/mine/7cyi) | Crystal structure of Alcohol dehydrogenase 1 from Artemisia annua | 分子名称: | Alcohol dehydrogenase 1, ZINC ION | 著者 | Feng, X, Fan, S, Lv, G, Li, M, Wu, G, Jin, Y, Yang, Z. | 登録日 | 2020-09-03 | 公開日 | 2021-09-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Crystal structure of Alcohol dehydrogenase 1 from Artemisia annua To Be Published
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5I6X
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![BU of 5i6x by Molmil](/molmil-images/mine/5i6x) | X-ray structure of the ts3 human serotonin transporter complexed with paroxetine at the central site | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, heavy chain, ... | 著者 | Coleman, J.A, Green, E.M, Gouaux, E. | 登録日 | 2016-02-16 | 公開日 | 2016-04-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | 主引用文献 | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
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4PHF
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![BU of 4phf by Molmil](/molmil-images/mine/4phf) | Crystal structure of Ypt7 covalently modified with GDP | 分子名称: | GTP-binding protein YPT7, MAGNESIUM ION, N-[3-(propanoylamino)propyl]guanosine 5'-(trihydrogen diphosphate), ... | 著者 | Vieweg, S, Wiegandt, D, Hofmann, F, Koch, D, Wu, Y, Itzen, A, Mueller, M.P, Goody, R.S. | 登録日 | 2014-05-06 | 公開日 | 2014-05-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Locking GTPases covalently in their functional states. Nat Commun, 6, 2015
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7DHS
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![BU of 7dhs by Molmil](/molmil-images/mine/7dhs) | Crystal Structure Analysis of the BRD4 | 分子名称: | 6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1R)-1-phenylethyl]benzo[cd]indol-2-one, Bromodomain-containing protein 4 | 著者 | Wu, T, Xiang, Q, Wang, C, Wu, C, Zhang, C, Zhang, M, Liu, Z, Zhang, Y, Xiao, L, Xu, Y. | 登録日 | 2020-11-17 | 公開日 | 2021-09-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Y06014 is a selective BET inhibitor for the treatment of prostate cancer. Acta Pharmacol.Sin., 42, 2021
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7DJS
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7DAI
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![BU of 7dai by Molmil](/molmil-images/mine/7dai) | The crystal structure of a serotonin N-acetyltransferase from Oryza Sativa | 分子名称: | Serotonin N-acetyltransferase 1, chloroplastic | 著者 | Zhou, Y.Z, Liao, L.J, Tang, T, Guo, Y, Liu, X.K, Liu, B, Zhao, Y.C. | 登録日 | 2020-10-16 | 公開日 | 2021-09-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and Molecular Dynamics Analysis of Plant Serotonin N-Acetyltransferase Reveal an Acid/Base-Assisted Catalysis in Melatonin Biosynthesis. Angew.Chem.Int.Ed.Engl., 60, 2021
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