5IPU

Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 6

Summary for 5IPU

Entry DOI	10.2210/pdb5ipu/pdb
Related	5IOU 5IOV 5IPQ 5IPR 5IPS 5IPT 5IPV
EMDB information	8097 8098 8101 8102 8103 8104 8105 8106
Descriptor	N-methyl-D-aspartate receptor subunit NR1-8a, Ionotropic glutamate receptor subunit NR2B (2 entities in total)
Functional Keywords	ligand-gated ion channel, synaptic transmission, signaling protein
Biological source	Xenopus laevis (African clawed frog) More
Total number of polymer chains	4
Total formula weight	371771.95
Authors	Zhu, S.,Stein, A.R.,Yoshioka, C.,Lee, C.H.,Goehring, A.,Mchaourab, S.H.,Gouaux, E. (deposition date: 2016-03-09, release date: 2016-04-20, Last modification date: 2024-03-06)
Primary citation	Zhu, S.,Stein, R.A.,Yoshioka, C.,Lee, C.H.,Goehring, A.,Mchaourab, H.S.,Gouaux, E. Mechanism of NMDA Receptor Inhibition and Activation. Cell, 165:704-714, 2016 Cited by PubMed: 27062927 DOI: 10.1016/j.cell.2016.03.028 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (15.4 Å)

Structure validation