PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

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2KUO	Structure and identification of ADP-ribose recognition motifs of APLF and role in the DNA damage response 分子名称: Aprataxin and PNK-like factor, ZINC ION 著者 Li, G.Y, McCulloch, R.D, Fenton, A, Cheung, M, Meng, L, Ikura, M, Koch, C.A. 登録日 2010-02-23 公開日 2010-05-05 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure and identification of ADP-ribose recognition motifs of aprataxin PNK-like factor (APLF) required for the interaction with sites of DNA damage response To be Published
2KUU	Solution Structure of K10 TLS RNA (GC mutant in upper helix) 分子名称: K10 TLS RNA 著者 Bullock, S.L, Ringel, I, Ish-Horowicz, D, Lukavsky, P.J. 登録日 2010-03-01 公開日 2010-05-19 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A'-form RNA helices are required for cytoplasmic mRNA transport in Drosophila. Nat.Struct.Mol.Biol., 17, 2010
2PU2	AmpC beta-lactamase with bound Phthalamide inhibitor 分子名称: 2-[(1R)-1-CARBOXY-2-(4-HYDROXYPHENYL)ETHYL]-1,3-DIOXOISOINDOLINE-5-CARBOXYLIC ACID, Beta-lactamase, PHOSPHATE ION 著者 Babaoglu, K, Shoichet, B.K. 登録日 2007-05-08 公開日 2008-04-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Comprehensive mechanistic analysis of hits from high-throughput and docking screens against beta-lactamase. J.Med.Chem., 51, 2008
2HPT	Crystal Structure of E. coli PepN (Aminopeptidase N)in complex with Bestatin 分子名称: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, Aminopeptidase N, GLYCEROL, ... 著者 Addlagatta, A, Matthews, B.W, Gay, L. 登録日 2006-07-17 公開日 2006-08-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of aminopeptidase N from Escherichia coli suggests a compartmentalized, gated active site. Proc.Natl.Acad.Sci.Usa, 103, 2006
2P23	Crystal structure of human FGF19 分子名称: Fibroblast growth factor 19 著者 Mohammadi, M. 登録日 2007-03-06 公開日 2007-04-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members. Mol.Cell.Biol., 27, 2007
4NH4	Structure of the binary complex of a zingiber officinale double bond reductase in complex with NADP 分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Zingiber officinale double bond reductase 著者 Langlois D'Estaintot, B, Buratto, J, Granier, T, Gallois, B, Willis, M.A, Sang, Y, Flores-Sanchez, I.J, Gang, D.R. 登録日 2013-11-04 公開日 2014-11-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of zingiber officinale double bond reductase To be Published
1QAW	Regulatory Features of the TRP Operon and the Crystal Structure of the TRP RNA-Binding Attenuation Protein from Bacillus Stearothermophilus. 分子名称: TRP RNA-BINDING ATTENUATION PROTEIN, TRYPTOPHAN 著者 Chen, X.-P, Antson, A.A, Yang, M, Baumann, C, Dodson, E.J, Dodson, G.G, Gollnick, P. 登録日 1999-03-31 公開日 1999-04-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Regulatory features of the trp operon and the crystal structure of the trp RNA-binding attenuation protein from Bacillus stearothermophilus. J.Mol.Biol., 289, 1999
2H3L	Crystal Structure of ERBIN PDZ 分子名称: LAP2 protein 著者 Appleton, B.A, Zhang, Y, Wu, P, Yin, J.P, Hunziker, W, Skelton, N.J, Sidhu, S.S, Wiesmann, C. 登録日 2006-05-22 公開日 2006-06-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity. J.Biol.Chem., 281, 2006
4MKA	Hepatitis C Virus polymerase NS5B genotype 1b (BK) in complex with inhibitor 13 (N-{2-[3-tert-butyl-2-methoxy-5-(2-oxo-1,2-dihydropyridin-3-yl)phenyl]-1,3-benzoxazol-5-yl}methanesulfonamide) 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, N-{3-[3-tert-butyl-2-methoxy-5-(2-oxo-1,2-dihydropyridin-3-yl)phenyl]-1-oxo-1H-isochromen-7-yl}methanesulfonamide, ... 著者 Harris, S.F, Wong, A. 登録日 2013-09-04 公開日 2013-10-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Discovery of a Novel Series of Potent Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B. J.Med.Chem., 56, 2013
2KNZ	NMR structure of CIP75 UBA domain 分子名称: Ubiquilin-4 著者 Kieken, F, Spagnol, G, Su, V, Lau, A.F, Sorgen, P.L. 登録日 2009-09-08 公開日 2010-03-16 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 NMR structure note: UBA domain of CIP75. J.Biomol.Nmr, 46, 2010
2KQE	Second PBZ domain of human APLF protein in complex with ribofuranosyladenosine 分子名称: ADENOSINE, Aprataxin and PNK-like factor, ZINC ION, ... 著者 Neuhaus, D, Eustermann, S, Brockmann, C, Yang, J. 登録日 2009-11-04 公開日 2010-01-19 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose). Nat.Struct.Mol.Biol., 17, 2010
3OKI	Crystal structure of human FXR in complex with (2S)-2-[2-(4-chlorophenyl)-1H-benzimidazol-1-yl]-N,2-dicyclohexylethanamide 分子名称: (2S)-2-[2-(4-chlorophenyl)-1H-benzimidazol-1-yl]-N,2-dicyclohexylethanamide, Bile acid receptor, peptide of Nuclear receptor coactivator 1 著者 Rudolph, M.G. 登録日 2010-08-25 公開日 2010-12-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetes Bioorg.Med.Chem.Lett., 21, 2010
3OMM	Crystal structure of human FXR in complex with 4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)-3-fluorobenzoic acid 分子名称: 4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)-3-fluorobenzoic acid, Bile acid receptor, peptide of Nuclear receptor coactivator 1 著者 Rudolph, M.G. 登録日 2010-08-27 公開日 2011-01-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Optimization of a novel class of benzimidazole-based farnesoid X receptor (FXR) agonists to improve physicochemical and ADME properties Bioorg.Med.Chem.Lett., 21, 2011
1XAC	CHIMERA ISOPROPYLMALATE DEHYDROGENASE BETWEEN BACILLUS SUBTILIS (M) AND THERMUS THERMOPHILUS (T) FROM N-TERMINAL: 20% T MIDDLE 20% M RESIDUAL 60% T, MUTATED AT S82R. LOW TEMPERATURE (100K) STRUCTURE. 分子名称: 3-ISOPROPYLMALATE DEHYDROGENASE 2T2M6T S82R 著者 Nagata, C, Moriyama, H, Tanaka, N. 登録日 1995-11-09 公開日 1996-04-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Cryocrystallography of 3-Isopropylmalate dehydrogenase from Thermus thermophilus and its chimeric enzyme. Acta Crystallogr.,Sect.D, 52, 1996
1XAD	CHIMERA ISOPROPYLMALATE DEHYDROGENASE BETWEEN BACILLUS SUBTILIS (M) AND THERMUS THERMOPHILUS (T) FROM N-TERMINAL: 20% T MIDDLE 20% M RESIDUAL 60% T, MUTATED AT S82R. LOW TEMPERATURE (150K) STRUCTURE. 分子名称: 3-ISOPROPYLMALATE DEHYDROGENASE 2T2M6T S82R 著者 Nagata, C, Moriyama, H, Tanaka, N. 登録日 1995-11-09 公開日 1996-04-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Cryocrystallography of 3-Isopropylmalate dehydrogenase from Thermus thermophilus and its chimeric enzyme. Acta Crystallogr.,Sect.D, 52, 1996
3OOK	Crystal structure of human FXR in complex with 4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)-3,5-difluorobenzoic acid 分子名称: 4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)-3,5-difluorobenzoic acid, Bile acid receptor, peptide of Nuclear receptor coactivator 1 著者 Rudolph, M.G. 登録日 2010-08-31 公開日 2011-01-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Optimization of a novel class of benzimidazole-based farnesoid X receptor (FXR) agonists to improve physicochemical and ADME properties Bioorg.Med.Chem.Lett., 21, 2011
2KYK	The sandwich region between two LMP2A PY motif regulates the interaction between AIP4WW2domain and PY motif 分子名称: E3 ubiquitin-protein ligase Itchy homolog 著者 Seo, M, Park, S, Seok, S, Kim, J, Cha, M, Lee, B. 登録日 2010-05-28 公開日 2011-06-01 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 The sandwich region between two LMP2A PY motif regulates the interaction between AIP4WW2domain and PY motif To be Published
2KUW	Solution Structure of K10 TLS RNA (A-form mutant in lower helix) 分子名称: K10 TLS RNA 著者 Bullock, S.L, Ringel, I, Ish-Horowicz, D, Lukavsky, P.J. 登録日 2010-03-01 公開日 2010-05-19 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A'-form RNA helices are required for cytoplasmic mRNA transport in Drosophila. Nat.Struct.Mol.Biol., 17, 2010
2KY6	Structure of ARC92VBD/MED25ACID 分子名称: Mediator of RNA polymerase II transcription subunit 25 著者 Milbradt, A.G, Sun, Z.J, Selenko, P, Takeuchi, K, Naar, A.M, Wagner, G. 登録日 2010-05-14 公開日 2011-03-09 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structure of the VP16 transactivator target in the Mediator. Nat.Struct.Mol.Biol., 18, 2011
3OKH	Crystal structure of human FXR in complex with 2-(4-chlorophenyl)-1-[(1S)-1-cyclohexyl-2-(cyclohexylamino)-2-oxoethyl]-1H-benzimidazole-6-carboxylic acid 分子名称: 2-(4-chlorophenyl)-1-[(1S)-1-cyclohexyl-2-(cyclohexylamino)-2-oxoethyl]-1H-benzimidazole-6-carboxylic acid, Bile acid receptor, peptide of Nuclear receptor coactivator 1 著者 Rudolph, M.G. 登録日 2010-08-25 公開日 2010-12-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetes Bioorg.Med.Chem.Lett., 21, 2010
3OMK	Crystal structure of human FXR in complex with (2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexyl-N-(2-methylphenyl)ethanamide 分子名称: (2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexyl-N-(2-methylphenyl)ethanamide, Bile acid receptor, peptide of Nuclear receptor coactivator 1 著者 Rudolph, M.G. 登録日 2010-08-27 公開日 2011-01-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Optimization of a novel class of benzimidazole-based farnesoid X receptor (FXR) agonists to improve physicochemical and ADME properties Bioorg.Med.Chem.Lett., 21, 2011
3AL3	Crystal Structure of TopBP1 BRCT7/8-BACH1 peptide complex 分子名称: DNA topoisomerase 2-binding protein 1, FORMIC ACID, Peptide of Fanconi anemia group J protein 著者 Leung, C.C, Glover, J.N. 登録日 2010-07-22 公開日 2010-12-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control J.Biol.Chem., 286, 2011
2H28	Crystal structure of YeeU from E. coli. Northeast Structural Genomics target ER304 分子名称: CHLORIDE ION, GLYCEROL, Hypothetical protein yeeU, ... 著者 Arbing, M, Su, M, Benach, J, Karpowich, N.K, Jiang, M, Xiao, R, Cunningham, K, Ma, L.-C, Chen, C.X, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2006-05-18 公開日 2006-07-18 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structures of Phd-Doc, HigA, and YeeU Establish Multiple Evolutionary Links between Microbial Growth-Regulating Toxin-Antitoxin Systems. Structure, 18, 2010
2KR9	Kalirin DH1 NMR structure 分子名称: Kalirin 著者 Gorbatyuk, V.Y, Schiller, M.R, Hoch, J.C. 登録日 2009-12-10 公開日 2010-12-15 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 The solution NMR structure of the first Dbl domain of RhoGEF Kalirin. To be Published
2KRK	Solution NMR Structure of 26S protease regulatory subunit 8 from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3102A 分子名称: 26S protease regulatory subunit 8 著者 Liu, G, Janjua, J, Xiao, R, Ciccosanti, C, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2009-12-18 公開日 2010-01-12 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of 26S protease regulatory subunit 8 from H.sapiens, Northeast Structural Genomics Consortium Target HR3102A To be Published

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