3SSK
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2O7I
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3SSW
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3STT
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3SU4
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![BU of 3su4 by Molmil](/molmil-images/mine/3su4) | Crystal structure of NS3/4A protease variant R155K in complex with vaniprevir | 分子名称: | (5R,7S,10S)-10-tert-butyl-N-{(1R,2R)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethylcyclopropyl}-15,15-dimethyl-3,9,12-trioxo-6,7,9,10,11,12,14,15,16,17,18,19-dodecahydro-1H,5H-2,23:5,8-dimethano-4,13,2,8,11-benzodioxatriazacyclohenicosine-7(3H)-carboxamide, NS3 protease,NS4A protein, SULFATE ION, ... | 著者 | Schiffer, C.A, Romano, K.P. | 登録日 | 2011-07-11 | 公開日 | 2012-09-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.255 Å) | 主引用文献 | The Molecular Basis of Drug Resistance against Hepatitis C Virus NS3/4A Protease Inhibitors. Plos Pathog., 8, 2012
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2O8H
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![BU of 2o8h by Molmil](/molmil-images/mine/2o8h) | Crystal structure of the catalytic domain of rat phosphodiesterase 10A | 分子名称: | 6,7-DIMETHOXY-4-{8-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]-3,4-DIHYDROISOQUINOLIN-2(1H)-YL}QUINAZOLINE, MAGNESIUM ION, Phosphodiesterase-10A, ... | 著者 | Pandit, J, Marr, E.S. | 登録日 | 2006-12-12 | 公開日 | 2007-01-09 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery of a series of 6,7-dimethoxy-4-pyrrolidylquinazoline PDE10A inhibitors J.Med.Chem., 50, 2007
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3DK8
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![BU of 3dk8 by Molmil](/molmil-images/mine/3dk8) | Catalytic cycle of human glutathione reductase near 1 A resolution | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE, GLYCEROL, ... | 著者 | Berkholz, D.S, Faber, H.R, Savvides, S.N, Karplus, P.A. | 登録日 | 2008-06-24 | 公開日 | 2008-08-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Catalytic cycle of human glutathione reductase near 1 A resolution. J.Mol.Biol., 382, 2008
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3T71
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![BU of 3t71 by Molmil](/molmil-images/mine/3t71) | Crystal Structure of Steccherinum ochraceum Laccase obtained by multi-crystals composite data collection technique (90% dose) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... | 著者 | Ferraroni, M, Briganti, F, Matera, I, Kolomytseva, M, Golovleva, L, Scozzafava, A, Chernykh, A.M. | 登録日 | 2011-07-29 | 公開日 | 2012-04-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Reaction intermediates and redox state changes in a blue laccase from Steccherinum ochraceum observed by crystallographic high/low X-ray dose experiments. J.Inorg.Biochem., 111, 2012
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3DCI
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![BU of 3dci by Molmil](/molmil-images/mine/3dci) | The Structure of a putative arylesterase from Agrobacterium tumefaciens str. C58 | 分子名称: | ACETIC ACID, Arylesterase, CHLORIDE ION, ... | 著者 | Cuff, M.E, Xu, X, Zheng, H, Binkowski, T.A, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2008-06-03 | 公開日 | 2008-09-30 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Structure of a putative arylesterase from Agrobacterium tumefaciens str. C58 TO BE PUBLISHED
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2ONP
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![BU of 2onp by Molmil](/molmil-images/mine/2onp) | Arg475Gln Mutant of Human Mitochondrial Aldehyde Dehydrogenase, complexed with NAD+ | 分子名称: | 1,2-ETHANEDIOL, Aldehyde dehydrogenase, GUANIDINE, ... | 著者 | Larson, H.N, Hurley, T.D. | 登録日 | 2007-01-24 | 公開日 | 2007-03-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487. J.Biol.Chem., 282, 2007
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3SV8
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![BU of 3sv8 by Molmil](/molmil-images/mine/3sv8) | Crystal structure of NS3/4A protease variant D168A in complex with Telaprevir | 分子名称: | (1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(2R,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxohexan-3-yl]octahydrocyclopenta[c]pyrrole-1-carboxamide, GLYCEROL, NS3 protease, ... | 著者 | Schiffer, C.A, Romano, K.P. | 登録日 | 2011-07-12 | 公開日 | 2012-09-05 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The Molecular Basis of Drug Resistance against Hepatitis C Virus NS3/4A Protease Inhibitors. Plos Pathog., 8, 2012
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3T88
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![BU of 3t88 by Molmil](/molmil-images/mine/3t88) | Crystal structure of Escherichia coli MenB in complex with substrate analogue, OSB-NCoA | 分子名称: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, CHLORIDE ION, GLYCEROL, ... | 著者 | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | 登録日 | 2011-08-01 | 公開日 | 2011-08-24 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member. Biochemistry, 50, 2011
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2OSY
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3SR2
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![BU of 3sr2 by Molmil](/molmil-images/mine/3sr2) | Crystal Structure of Human XLF-XRCC4 Complex | 分子名称: | DNA repair protein XRCC4, Non-homologous end-joining factor 1 | 著者 | Hammel, M, Classen, S, Tainer, J.A. | 登録日 | 2011-07-06 | 公開日 | 2011-07-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.9708 Å) | 主引用文献 | XRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair. J.Biol.Chem., 286, 2011
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3FYI
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![BU of 3fyi by Molmil](/molmil-images/mine/3fyi) | Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides in the reduced state bound with cyanide | 分子名称: | CADMIUM ION, CALCIUM ION, COPPER (I) ION, ... | 著者 | Qin, L, Mills, D.A, Proshlyakov, D.A, Hiser, C, Ferguson-Miller, S. | 登録日 | 2009-01-22 | 公開日 | 2009-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Redox dependent conformational changes in cytochrome c oxidase suggest a gating mechanism for proton uptake. Biochemistry, 48, 2009
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3SYC
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2OV1
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3SS0
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3SS8
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![BU of 3ss8 by Molmil](/molmil-images/mine/3ss8) | Crystal structure of NFeoB from S. thermophilus bound to GDP.AlF4- and K+ | 分子名称: | Ferrous iron uptake transporter protein B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Ash, M.R, Maher, M.J, Guss, J.M, Jormakka, M. | 登録日 | 2011-07-08 | 公開日 | 2011-08-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | The initiation of GTP hydrolysis by the G-domain of FeoB: insights from a transition-state complex structure Plos One, 6, 2011
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3SSH
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2OVE
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![BU of 2ove by Molmil](/molmil-images/mine/2ove) | Crystal Structure of Recombinant Human Complement Protein C8gamma | 分子名称: | Complement component 8, gamma polypeptide | 著者 | Chiswell, B, Lovelace, L.L, Brannen, C, Ortlund, E.A, Lebioda, L, Sodetz, J.M. | 登録日 | 2007-02-13 | 公開日 | 2007-05-22 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural features of the ligand binding site on human complement protein C8gamma: A member of the lipocalin family Biochim.Biophys.Acta, 1774, 2007
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3FQV
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![BU of 3fqv by Molmil](/molmil-images/mine/3fqv) | Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3-methoxy-4-phenylphenyl)but-1-ynyl]-6-methylpyrimidine | 分子名称: | 5-[(3S)-3-(2-methoxybiphenyl-4-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Trimethoprim-sensitive dihydrofolate reductase | 著者 | Anderson, A.C, Frey, K.M, Liu, J, Lombardo, M.N. | 登録日 | 2009-01-07 | 公開日 | 2009-03-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance. J.Mol.Biol., 387, 2009
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3SU3
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![BU of 3su3 by Molmil](/molmil-images/mine/3su3) | Crystal structure of NS3/4A protease in complex with vaniprevir | 分子名称: | (5R,7S,10S)-10-tert-butyl-N-{(1R,2R)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethylcyclopropyl}-15,15-dimethyl-3,9,12-trioxo-6,7,9,10,11,12,14,15,16,17,18,19-dodecahydro-1H,5H-2,23:5,8-dimethano-4,13,2,8,11-benzodioxatriazacyclohenicosine-7(3H)-carboxamide, NS3 protease, NS4A protein, ... | 著者 | Schiffer, C.A, Romano, K.P. | 登録日 | 2011-07-11 | 公開日 | 2012-09-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The Molecular Basis of Drug Resistance against Hepatitis C Virus NS3/4A Protease Inhibitors. Plos Pathog., 8, 2012
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3SUG
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![BU of 3sug by Molmil](/molmil-images/mine/3sug) | Crystal structure of NS3/4A protease variant A156T in complex with MK-5172 | 分子名称: | (1aR,5S,8S,10R,22aR)-5-tert-butyl-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}-14-methoxy-3,6-di oxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadec ino[11,12-b]quinoxaline-8-carboxamide, NS3 protease, NS4A protein, ... | 著者 | Schiffer, C.A, Romano, K.P. | 登録日 | 2011-07-11 | 公開日 | 2012-09-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Molecular Basis of Drug Resistance against Hepatitis C Virus NS3/4A Protease Inhibitors. Plos Pathog., 8, 2012
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2OXV
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