3SR2

Crystal Structure of Human XLF-XRCC4 Complex

Summary for 3SR2

Entry DOI	10.2210/pdb3sr2/pdb
Descriptor	DNA repair protein XRCC4, Non-homologous end-joining factor 1 (2 entities in total)
Functional Keywords	xrcc4, xlf, nhej, dna repair, dna, dna ligases, dna-binding proteins, dimerization, humans, protein structure, quaternary, complex, non-homologous end joining (nhej), dna ligase iv, ku, xlf-xrcc4, protein dna-interaction, dna binding protein-protein binding complex, dna binding protein/protein binding
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: Q13426 Q9H9Q4
Total number of polymer chains	8
Total formula weight	168501.06
Authors	Hammel, M.,Classen, S.,Tainer, J.A. (deposition date: 2011-07-06, release date: 2011-07-20, Last modification date: 2023-09-13)
Primary citation	Hammel, M.,Rey, M.,Yu, Y.,Mani, R.S.,Classen, S.,Liu, M.,Pique, M.E.,Fang, S.,Mahaney, B.L.,Weinfeld, M.,Schriemer, D.C.,Lees-Miller, S.P.,Tainer, J.A. XRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair. J.Biol.Chem., 286:32638-32650, 2011 Cited by PubMed: 21775435 DOI: 10.1074/jbc.M111.272641 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.9708 Å)

Structure validation