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4R66
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Ternary complex crystal structure of E295K mutant of DNA polymerase Beta
分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
著者Batra, V.K, Beard, W.A, Wilson, S.H.
登録日2014-08-22
公開日2014-10-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Substrate-induced DNA Polymerase beta Activation.
J.Biol.Chem., 289, 2014
3ADB
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BU of 3adb by Molmil
Crystal structure of O-phosphoseryl-tRNA kinase complexed with selenocysteine tRNA and AMPPNP (crystal type 1)
分子名称: L-seryl-tRNA(Sec) kinase, MAGNESIUM ION, PHOSPHATE ION, ...
著者Itoh, Y, Chiba, S, Sekine, S, Yokoyama, S.
登録日2010-01-18
公開日2010-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for the Major Role of O-Phosphoseryl-tRNA Kinase in the UGA-Specific Encoding of Selenocysteine
Mol.Cell, 39, 2010
3C2M
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BU of 3c2m by Molmil
Ternary complex of DNA POLYMERASE BETA with a G:dAPCPP mismatch in the active site
分子名称: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine, DNA (5'-D(*DCP*DCP*DGP*DAP*DCP*DGP*DGP*DCP*DGP*DCP*DAP*DTP*DCP*DAP*DGP*DC)-3'), ...
著者Batra, V.K, Beard, W.A, Shock, D.D, Pedersen, L.C, Wilson, S.H.
登録日2008-01-25
公開日2008-05-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structures of DNA polymerase beta with active-site mismatches suggest a transient abasic site intermediate during misincorporation.
Mol.Cell, 30, 2008
3C2L
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BU of 3c2l by Molmil
Ternary complex of DNA POLYMERASE BETA with a C:DAPCPP mismatch in the active site
分子名称: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine, DNA (5'-D(*DCP*DCP*DGP*DAP*DCP*DCP*DGP*DCP*DGP*DCP*DAP*DTP*DCP*DAP*DGP*DC)-3'), DNA (5'-D(*DGP*DCP*DTP*DGP*DAP*DTP*DGP*DCP*DGP*DC)-3'), ...
著者Batra, V.K, Beard, W.A, Shock, D.D, Pedersen, L.C, Wilson, S.H.
登録日2008-01-25
公開日2008-05-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of DNA polymerase beta with active-site mismatches suggest a transient abasic site intermediate during misincorporation.
Mol.Cell, 30, 2008
7UNK
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BU of 7unk by Molmil
Structure of Importin-4 bound to the H3-H4-ASF1 histone-histone chaperone complex
分子名称: Histone H3, Histone H4, Histone chaperone, ...
著者Bernardes, N.E, Chook, Y.M, Fung, H.Y.J, Chen, Z, Li, Y.
登録日2022-04-11
公開日2022-09-21
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Structure of IMPORTIN-4 bound to the H3-H4-ASF1 histone-histone chaperone complex.
Proc.Natl.Acad.Sci.USA, 119, 2022
3ADC
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BU of 3adc by Molmil
Crystal structure of O-phosphoseryl-tRNA kinase complexed with selenocysteine tRNA and AMPPNP (crystal type 2)
分子名称: L-seryl-tRNA(Sec) kinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Itoh, Y, Chiba, S, Sekine, S, Yokoyama, S.
登録日2010-01-18
公開日2010-07-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural Basis for the Major Role of O-Phosphoseryl-tRNA Kinase in the UGA-Specific Encoding of Selenocysteine
Mol.Cell, 39, 2010
3ADD
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Crystal structure of O-phosphoseryl-tRNA kinase complexed with selenocysteine tRNA and AMPPNP (crystal type 3)
分子名称: L-seryl-tRNA(Sec) kinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Itoh, Y, Chiba, S, Sekine, S, Yokoyama, S.
登録日2010-01-18
公開日2010-07-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for the Major Role of O-Phosphoseryl-tRNA Kinase in the UGA-Specific Encoding of Selenocysteine
Mol.Cell, 39, 2010
3ISD
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BU of 3isd by Molmil
Ternary complex of human DNA polymerase beta with an abasic site (THF): DAPCPP mismatch
分子名称: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine, 5'-D(*CP*CP*GP*AP*CP*(3DR)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', ...
著者Beard, W.A, Shock, D.D, Batra, V.K, Pedersen, L.C, Wilson, S.H.
登録日2009-08-25
公開日2009-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献DNA polymerase beta substrate specificity: side chain modulation of the "A-rule".
J.Biol.Chem., 284, 2009
1FHK
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BU of 1fhk by Molmil
NMR STRUCTURE OF THE 690 LOOP OF 16 S RRNA OF E. COLI
分子名称: RNA (5'-R(*GP*GP*CP*GP*GP*UP*GP*AP*AP*AP*UP*GP*CP*C)-3')
著者Morosyuk, S.V, Cunningham, P.R, SantaLucia Jr, J.
登録日2000-08-01
公開日2001-03-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and function of the conserved 690 hairpin in Escherichia coli 16 S ribosomal RNA. II. NMR solution structure.
J.Mol.Biol., 307, 2001
6SA0
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BU of 6sa0 by Molmil
Ternary complex of Prim-PolC from Mycobacterium smegmatis with 2nt gapped DNA and UpNHpp
分子名称: 1,2-ETHANEDIOL, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, CACODYLATE ION, ...
著者Brissett, N.C, Doherty, A.J.
登録日2019-07-15
公開日2020-11-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.209 Å)
主引用文献Molecular basis for DNA repair synthesis on short gaps by mycobacterial Primase-Polymerase C.
Nat Commun, 11, 2020
1ZP2
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BU of 1zp2 by Molmil
Structure of the Mediator subunit cyclin C
分子名称: RNA polymerase II holoenzyme cyclin-like subunit
著者Hoeppner, S, Baumli, S, Cramer, P.
登録日2005-05-16
公開日2005-07-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the Mediator Subunit Cyclin C and its Implications for CDK8 Function.
J.Mol.Biol., 350, 2005
8B9K
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BU of 8b9k by Molmil
Cryo-EM structure of MLE in complex with ADP:AlF4 and SL7modUUC RNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, SL7modUUC, ...
著者Jagtap, P.K.A, Hennig, J.
登録日2022-10-06
公開日2023-10-18
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.04 Å)
主引用文献Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.
Mol.Cell, 83, 2023
4N5S
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BU of 4n5s by Molmil
Ternary complex structure of Klenow fragment of Taq DNA polymerase I707L mutant (Cs3C KlenTaq) with DNA and ddCTP
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-D(*AP*A*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', ...
著者Wu, E.Y.
登録日2013-10-10
公開日2015-01-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献A Conservative Isoleucine to Leucine Mutation Causes Major Rearrangements and Cold Sensitivity in KlenTaq1 DNA Polymerase.
Biochemistry, 54, 2015
2L41
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BU of 2l41 by Molmil
Nab3 RRM - UCUU complex
分子名称: RNA (5'-R(P*UP*CP*UP*U)-3'), RRM domain from Nuclear polyadenylated RNA-binding protein 3
著者Stefl, R, Pergoli, R, Hobor, F, Kubicek, K, Zimmermann, M, Pasulka, J, Hofr, C.
登録日2010-09-28
公開日2010-11-17
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Recognition of transcription termination signal by the nuclear polyadenylated RNA-binding (NAB) 3 protein
J.Biol.Chem., 286, 2011
8VFA
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BU of 8vfa by Molmil
Ternary DNA Polymerase Beta bound to DNA containing primer terminal dC base-paired with FapydG
分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*CP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
著者Oden, P.N, Ryan, B.J, Freudenthal, B.D.
登録日2023-12-21
公開日2024-05-08
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
8VFB
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BU of 8vfb by Molmil
Ternary DNA Polymerase Beta bound to DNA containing primer terminal dA base-paired with FapydG
分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*CP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
著者Oden, P.N, Ryan, B.J, Freudenthal, B.D.
登録日2023-12-21
公開日2024-05-08
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
8VFD
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Ternary DNA Polymerase Beta bound to DNA containing template FapydG incoming TTP analog
分子名称: 1-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]-beta-D-threo-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione, DNA (5'-D(*CP*CP*GP*AP*CP*(FAP)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
著者Oden, P.N, Ryan, B.J, Freudenthal, B.D.
登録日2023-12-21
公開日2024-05-08
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
4L1P
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BU of 4l1p by Molmil
Crystal Structure of Human Rtf1 Plus3 domain
分子名称: GLYCEROL, RNA polymerase-associated protein RTF1 homolog
著者Wier, A.D, Heroux, A, VanDemark, A.P.
登録日2013-06-03
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.
Proc.Natl.Acad.Sci.USA, 110, 2013
4L1U
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Crystal Structure of Human Rtf1 Plus3 Domain in Complex with Spt5 CTR Phosphopeptide
分子名称: GLYCEROL, RNA polymerase-associated protein RTF1 homolog, SULFATE ION, ...
著者Wier, A.D, Heroux, A, VanDemark, A.P.
登録日2013-06-03
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.424 Å)
主引用文献Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.
Proc.Natl.Acad.Sci.USA, 110, 2013
3PKY
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BU of 3pky by Molmil
Polymerase Domain from Mycobacterium tuberculosis Ligase D in complex with DNA, UTP and Manganese.
分子名称: DNA 5'-D(*G*CP*CP*GP*CP*AP*AP*CP*GP*CP*AP*CP*G)-3', DNA 5'-D(P*GP*CP*GP*GP*C)-3', MANGANESE (II) ION, ...
著者Brissett, N.C, Fox, G.C, Pitcher, R.S, Doherty, A.J.
登録日2010-11-12
公開日2011-02-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of a Preternary Complex Involving a Prokaryotic NHEJ DNA Polymerase.
Mol.Cell, 41, 2011
4M8O
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TERNARY COMPLEX OF DNA POLYMERASE EPSILON WITH AN INCOMING dATP
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2-AMINOETHANESULFONIC ACID, CHLORIDE ION, ...
著者Sauer-Eriksson, A.E, Hogg, M, Osterman, P, Johansson, E.
登録日2013-08-13
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for processive DNA synthesis by yeast DNA polymerase epsilon.
Nat.Struct.Mol.Biol., 21, 2014
1O4X
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TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT
分子名称: 5'-D(*CP*AP*TP*TP*AP*GP*CP*AP*TP*GP*AP*CP*AP*AP*AP*GP*AP*CP*A)-3', 5'-D(*TP*GP*TP*CP*TP*TP*TP*GP*TP*CP*AP*TP*GP*CP*TP*AP*AP*TP*G)-3', Transcription factor SOX-2, ...
著者Clore, G.M, Williams, D.C.
登録日2003-07-17
公開日2004-01-27
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex.
J.Biol.Chem., 279, 2004
1HKN
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A complex between acidic fibroblast growth factor and 5-amino-2-naphthalenesulfonate
分子名称: 5-AMINO-NAPHTALENE-2-MONOSULFONATE, HEPARIN-BINDING GROWTH FACTOR 1
著者Fernandez-Tornero, C, Lozano, R.M, Gimenez-Gallego, G, Romero, A.
登録日2003-03-10
公開日2004-03-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Leads for Development of New Naphthalenesulfonate Derivatives with Enhanced Antiangiogenic Activity: Crystal Structure of Acidic Fibroblast Growth Factor in Complex with 5-Amino-2-Naphthalenesulfonate
J.Biol.Chem., 278, 2003
3QLM
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Crystal structure of porcine pancreatic phospholipase A2 in complex with n-hexadecanoic acid
分子名称: CALCIUM ION, PALMITIC ACID, Phospholipase A2, ...
著者Aparna, V, Dileep, K.V, Karthe, P, Mandal, P.K, Sadasivan, C, Haridas, M.
登録日2011-02-03
公開日2011-04-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Anti-inflammatory property of n-hexadecanoic acid: Structural evidence and Kinetic assessment.
Chem.Biol.Drug Des., 2012
4K0R
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Crystal structure of mouse Cryptochrome 1
分子名称: Cryptochrome-1
著者Czarna, A, Wolf, E.
登録日2013-04-04
公開日2013-06-26
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structures of Drosophila cryptochrome and mouse cryptochrome1 provide insight into circadian function.
Cell(Cambridge,Mass.), 153, 2013

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件を2024-08-07に公開中

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