1HKN

A complex between acidic fibroblast growth factor and 5-amino-2-naphthalenesulfonate

Summary for 1HKN

Entry DOI	10.2210/pdb1hkn/pdb
Related	1AXM 1DJS 1DZC 1DZD 1E0O 1EVT 1JQZ 1JT3 1JT4 1JT5 1JT7 1JTC 1K5U 1K5V 1QCT 1RML 2AFG 2AXM
Descriptor	HEPARIN-BINDING GROWTH FACTOR 1, 5-AMINO-NAPHTALENE-2-MONOSULFONATE (3 entities in total)
Functional Keywords	growth factor, mitogen, angiogenesis, heparin-binding
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	6
Total formula weight	94710.64
Authors	Fernandez-Tornero, C.,Lozano, R.M.,Gimenez-Gallego, G.,Romero, A. (deposition date: 2003-03-10, release date: 2004-03-11, Last modification date: 2023-12-13)
Primary citation	Fernandez-Tornero, C.,Lozano, R.M.,Redondo-Horcajo, M.,Gomez, A.,Lopez, J.,Quesada, E.,Uriel, C.,Valverde, S.,Cuevas, P.,Romero, A.,Gimenez-Gallego, G. Leads for Development of New Naphthalenesulfonate Derivatives with Enhanced Antiangiogenic Activity: Crystal Structure of Acidic Fibroblast Growth Factor in Complex with 5-Amino-2-Naphthalenesulfonate J.Biol.Chem., 278:21774-, 2003 Cited by PubMed: 12676958 DOI: 10.1074/JBC.M212833200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation