1JTC

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE (L44F)

Summary for 1JTC

• Entry DOI: 10.2210/pdb1jtc/pdb
• Related: 1JQZ
• Descriptor: acidic fibroblast growth factor, FORMIC ACID (3 entities in total)
• Functional Keywords: beta-trefoil, hormone-growth factor complex, hormone/growth factor
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P05230
• Total number of polymer chains: 4
• Total formula weight: 67251.26

Authors

Brych, S.R.,Blaber, S.I.,Logan, T.M.,Blaber, M. (deposition date: 2001-08-20, release date: 2001-12-19, Last modification date: 2023-08-16)

• Primary citation: Brych, S.R.,Blaber, S.I.,Logan, T.M.,Blaber, M.; Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.; Protein Sci., 10:2587-2599, 2001; PubMed: 11714927; DOI: 10.1110/ps.ps.34701

Experimental method

X-RAY DIFFRACTION (1.7 Å)