2AXM
HEPARIN-LINKED BIOLOGICALLY-ACTIVE DIMER OF FIBROBLAST GROWTH FACTOR
Summary for 2AXM
Entry DOI | 10.2210/pdb2axm/pdb |
Descriptor | ACIDIC FIBROBLAST GROWTH FACTOR, 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose (3 entities in total) |
Functional Keywords | human acidic fibroblast growth factor, heparin decasaccharide, hexagonal crystal form, growth factor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 32328.83 |
Authors | Digabriele, A.D.,Lax, I.,Chen, D.I.,Svahn, C.M.,Jaye, M.,Schlessinger, J.,Hendrickson, W.A. (deposition date: 1997-10-20, release date: 1998-04-22, Last modification date: 2024-05-22) |
Primary citation | DiGabriele, A.D.,Lax, I.,Chen, D.I.,Svahn, C.M.,Jaye, M.,Schlessinger, J.,Hendrickson, W.A. Structure of a heparin-linked biologically active dimer of fibroblast growth factor. Nature, 393:812-817, 1998 Cited by PubMed: 9655399DOI: 10.1038/31741 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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