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4W2H
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Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (co-crystallized), mRNA and deacylated tRNA in the P site
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V.
登録日2014-09-12
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
4V6Q
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Structural characterization of mRNA-tRNA translocation intermediates (class 5 of the six classes)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J.
登録日2011-12-08
公開日2014-07-09
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (11.5 Å)
主引用文献Structural characterization of mRNA-tRNA translocation intermediates.
Proc.Natl.Acad.Sci.USA, 109, 2012
4V73
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E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in hybrid pre-translocation state (pre5a)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
登録日2013-10-14
公開日2014-07-09
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (15 Å)
主引用文献Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V9Q
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Crystal Structure of Blasticidin S Bound to Thermus Thermophilus 70S Ribosome.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Svidritskiy, E, Ling, C, Ermolenko, D.N, Korostelev, A.A.
登録日2013-06-12
公開日2014-07-09
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome.
Proc.Natl.Acad.Sci.USA, 110, 2013
4V9J
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70S ribosome translocation intermediate GDPNP-II containing elongation factor EFG/GDPNP, mRNA, and tRNA bound in the pe*/E state.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Zhou, J, Lancaster, L, Donohue, J.P, Noller, H.F.
登録日2013-04-23
公開日2014-07-09
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.86 Å)
主引用文献Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation.
Science, 340, 2013
4V4Q
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Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Schuwirth, B.S, Borovinskaya, M.A, Hau, C.W, Zhang, W, Vila-Sanjurjo, A, Holton, J.M, Cate, J.H.D.
登録日2005-08-30
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.46 Å)
主引用文献Structures of the bacterial ribosome at 3.5 A resolution.
Science, 310, 2005
4V5E
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Insights into translational termination from the structure of RF2 bound to the ribosome
分子名称: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Weixlbaumer, A, Jin, H, Neubauer, C, Voorhees, R.M, Petry, S, Kelley, A.C, Ramakrishnan, V.
登録日2009-04-30
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Insights Into Translational Termination from the Structure of Rf2 Bound to the Ribosome.
Science, 322, 2008
4W2I
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Crystal structure of the Thermus thermophilus 70S ribosome in complex with negamycin, mRNA and three deacylated tRNAs in the A, P and E sites
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Szal, T, Jiang, F, Gupta, P, Matsuda, R, Shiozuka, M, Steitz, T.A, Vazquez-Laslop, N, Mankin, A.S.
登録日2014-09-12
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Negamycin Interferes with Decoding and Translocation by Simultaneous Interaction with rRNA and tRNA.
Mol.Cell, 56, 2014
4V42
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Crystal structure of the ribosome at 5.5 A resolution.
分子名称: 30S 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Yusupov, M.M, Yusupova, G.Z, Baucom, A, Lieberman, K, Earnest, T.N, Cate, J.H.D, Noller, H.F.
登録日2001-03-30
公開日2014-07-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (5.5 Å)
主引用文献Crystal structure of the ribosome at 5.5 A resolution
Science, 292, 2001
4V6N
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Structural characterization of mRNA-tRNA translocation intermediates (50S ribosome of class2 of the six classes)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J.
登録日2011-12-07
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (12.1 Å)
主引用文献Structural characterization of mRNA-tRNA translocation intermediates.
Proc.Natl.Acad.Sci.USA, 109, 2012
4V72
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E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in hybrid pre-translocation state (pre4)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
登録日2013-10-14
公開日2014-07-09
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (13 Å)
主引用文献Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V7P
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Recognition of the amber stop codon by release factor RF1.
分子名称: 16S rRNA (1504-MER), 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Korostelev, A, Zhu, J, Asahara, H, Noller, H.F.
登録日2010-04-29
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.62 Å)
主引用文献Recognition of the amber UAG stop codon by release factor RF1.
Embo J., 29, 2010
4V88
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The structure of the eukaryotic ribosome at 3.0 A resolution.
分子名称: 18S RIBOSOMAL RNA, 18S rRNA, 25S rRNA, ...
著者Ben-Shem, A, Garreau de Loubresse, N, Melnikov, S, Jenner, L, Yusupova, G, Yusupov, M.
登録日2011-10-11
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of the eukaryotic ribosome at 3.0 angstrom resolution.
Science, 334, 2011
4V4H
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Crystal structure of the bacterial ribosome from Escherichia coli in complex with the antibiotic kasugamyin at 3.5A resolution.
分子名称: (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE, 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, ...
著者Schuwirth, B.S, Vila-Sanjurjo, A, Cate, J.H.D.
登録日2006-08-04
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.46 Å)
主引用文献Structural analysis of kasugamycin inhibition of translation.
Nat.Struct.Mol.Biol., 13, 2006
4V4J
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Interactions and Dynamics of the Shine-Dalgarno Helix in the 70S Ribosome.
分子名称: 16S RNA, 23S LARGE SUBUNIT RIBOSOMAL RNA, 30S ribosomal protein S10, ...
著者Korostelev, A, Trakhanov, S, Asahara, H, Laurberg, M, Noller, H.F.
登録日2007-07-18
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.83 Å)
主引用文献Interactions and dynamics of the Shine Dalgarno helix in the 70S ribosome.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4V4Z
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70S Thermus thermophilous ribosome functional complex with mRNA and E- and P-site tRNAs at 4.5A.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Jenner, L, Yusupova, G, Rees, B, Moras, D, Yusupov, M.
登録日2006-06-27
公開日2014-07-09
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (4.51 Å)
主引用文献Structural basis for messenger RNA movement on the ribosome.
Nature, 444, 2006
4V5D
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Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated A- and P-site tRNAs, and E-site tRNA.
分子名称: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Voorhees, R.M, Weixlbaumer, A, Loakes, D, Kelley, A.C, Ramakrishnan, V.
登録日2009-03-24
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome.
Nat. Struct. Mol. Biol., 16, 2009
4V57
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Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin and neomycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Borovinskaya, M.A, Shoji, S, Holton, J.M, Fredrick, K, Cate, J.H.D.
登録日2007-07-21
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献A steric block in translation caused by the antibiotic spectinomycin.
Acs Chem.Biol., 2, 2007
4V9R
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Crystal structure of antibiotic DITYROMYCIN bound to 70S ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A.
登録日2013-12-05
公開日2014-07-09
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.
Cell Rep, 6, 2014
4V6P
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Structural characterization of mRNA-tRNA translocation intermediates (class 4b of the six classes)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J.
登録日2011-12-08
公開日2014-07-09
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (13.5 Å)
主引用文献Structural characterization of mRNA-tRNA translocation intermediates.
Proc.Natl.Acad.Sci.USA, 109, 2012
4V4Y
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BU of 4v4y by Molmil
Crystal structure of the 70S Thermus thermophilus ribosome with translocated and rotated Shine-Dalgarno Duplex.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Jenner, L, Yusupova, G, Rees, B, Moras, D, Yusupov, M.
登録日2006-06-27
公開日2014-07-09
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (5.5 Å)
主引用文献Structural basis for messenger RNA movement on the ribosome.
Nature, 444, 2006
4V71
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E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate pre-translocation state (pre2)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
登録日2013-10-14
公開日2014-07-09
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V5C
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Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated A-site tRNA, deacylated P-site tRNA, and E-site tRNA.
分子名称: 16S ribosomal RNA, 23S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Voorhees, R.M, Weixlbaumer, A, Loakes, D, Kelley, A.C, Ramakrishnan, V.
登録日2009-03-24
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Insights Into Substrate Stabilization from Snapshots of the Peptidyl Transferase Center of the Intact 70S Ribosome
Nat.Struct.Mol.Biol., 16, 2009
4V5R
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The crystal structure of EF-Tu and Trp-tRNA-Trp bound to a cognate codon on the 70S ribosome.
分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V.
登録日2010-12-07
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
4V9M
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70S Ribosome translocation intermediate FA-4.2A containing elongation factor EFG/FUSIDIC ACID/GDP, mRNA, and tRNA bound in the pe*/E state.
分子名称: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Zhou, J, Lancaster, L, Donohue, J.P, Noller, H.F.
登録日2013-04-25
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation.
Science, 340, 2013

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