PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

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4OE7	Crystal structure of YagE, a KDG aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal 分子名称: (4R)-4-hydroxy-2,5-dioxopentanoic acid, (4S)-4-hydroxy-2,5-dioxopentanoic acid, 1,2-ETHANEDIOL, ... 著者 Manoj Kumar, P, Baskar, V, Manicka, S, Krishnaswamy, S. 登録日 2014-01-12 公開日 2014-12-24 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Crystal structure of YagE, a KDG aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal To be Published
4OEP	Crystal structure of the ZO-1 PDZ1 domain in complex with the 7-mer Claudin1 C-terminal tail 分子名称: ACETATE ION, DODECAETHYLENE GLYCOL, Tight junction protein ZO-1 著者 Nomme, J, Lavie, A. 登録日 2014-01-13 公開日 2015-01-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural Basis of a Key Factor Regulating the Affinity between the Zonula Occludens First PDZ Domain and Claudins. J.Biol.Chem., 290, 2015
4OQ8	Satellite Tobacco Mosaic Virus Refined to 1.4 A Resolution using icosahedral constraints 分子名称: Coat protein, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Larson, S.B, Day, J.S, McPherson, A. 登録日 2014-02-07 公開日 2014-09-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Satellite tobacco mosaic virus refined to 1.4 angstrom resolution. Acta Crystallogr.,Sect.D, 70, 2014
4OF1	crystal structure of toxin from staphylococcus aureus Mu50 分子名称: mRNA interferase MazF 著者 Park, J.Y, Im, H, Seok, S.H, Lee, B.J. 登録日 2014-01-14 公開日 2015-01-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural Insights into the toxin from Staphylococcus aureus Mu50 To be Published
4OFH	Structural basis for thymine glycosylase activity on T:O6-methylG mismatch by methyl-CpG binding domain protein 4: Implications for roles of Arg468 in mismatch recognition and catalysis 分子名称: 12-mer DNA(O6MeG), 12-mer DNA(T), MAGNESIUM ION, ... 著者 Ouzon-Shubeita, H, Lin, Y.-L, Lee, S. 登録日 2014-01-14 公開日 2015-04-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Structure of MBD4 bound to O6MeG:T mispair DNA To be Published
4OQT	LINGO-1/Li81 Fab complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Li81 Fab, ... 著者 Pepinsky, R.B, Arndt, J.W, Quan, C, Gao, Y, Quintero-Monzon, O, Lee, X, Mi, S. 登録日 2014-02-10 公開日 2014-05-14 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.23 Å) 主引用文献 Structure of the LINGO-1-Anti-LINGO-1 Li81 Antibody Complex Provides Insights into the Biology of LINGO-1 and the Mechanism of Action of the Antibody Therapy. J.Pharmacol.Exp.Ther., 350, 2014
4YSC	Completely oxidized structure of copper nitrite reductase from Alcaligenes faecalis 分子名称: CHLORIDE ION, COPPER (II) ION, Copper-containing nitrite reductase 著者 Fukuda, Y, Tse, K.M, Suzuki, M, Diederichs, K, Hirata, K, Nakane, T, Sugahara, M, Nango, E, Tono, K, Joti, Y, Kameshima, T, Song, C, Hatsui, T, Yabashi, M, Nureki, O, Matsumura, H, Inoue, T, Iwata, S, Mizohata, E. 登録日 2015-03-17 公開日 2016-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Redox-coupled proton transfer mechanism in nitrite reductase revealed by femtosecond crystallography Proc.Natl.Acad.Sci.USA, 113, 2016
4ORI	Rat dihydroorotate dehydrogenase bound with DSM338 (N-[3,5-difluoro-4-(trifluoromethyl)phenyl]-5-methyl-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine) 分子名称: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ... 著者 Deng, X, Phillips, M.A. 登録日 2014-02-11 公開日 2014-06-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Fluorine Modulates Species Selectivity in the Triazolopyrimidine Class of Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors. J.Med.Chem., 57, 2014
4YSR	Structure of copper nitrite reductase from Geobacillus thermodenitrificans - 16.6 MGy 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, COPPER (II) ION, Nitrite reductase, ... 著者 Fukuda, Y, Tse, K.M, Suzuki, M, Diederichs, K, Hirata, K, Nakane, T, Sugahara, M, Nango, E, Tono, K, Joti, Y, Kameshima, T, Song, C, Hatsui, T, Yabashi, M, Nureki, O, Matsumura, H, Inoue, T, Iwata, S, Mizohata, E. 登録日 2015-03-17 公開日 2016-02-24 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Redox-coupled structural changes in nitrite reductase revealed by serial femtosecond and microfocus crystallography J.Biochem., 159, 2016
4OG3	Human menin with bound inhibitor MIV-3R 分子名称: 4-(3-{4-[(R)-cyclopentyl(hydroxy)phenylmethyl]piperidin-1-yl}propoxy)benzonitrile, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... 著者 He, S, Senter, T.J, Pollock, J.W, Han, C, Upadhyay, S.K, Purohit, T, Gogliotti, R.D, Lindsley, C.W, Cierpicki, T, Stauffer, S.R, Grembecka, J. 登録日 2014-01-15 公開日 2014-03-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 High-Affinity Small-Molecule Inhibitors of the Menin-Mixed Lineage Leukemia (MLL) Interaction Closely Mimic a Natural Protein-Protein Interaction. J.Med.Chem., 57, 2014
4YIO	X-ray structure of the iron/manganese cambialistic superoxide dismutase from Streptococcus thermophilus 分子名称: FE (III) ION, GLYCEROL, SULFATE ION, ... 著者 Russo Krauss, I, Merlino, A, Pica, A, Sica, F. 登録日 2015-03-02 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Fine tuning of metal-specific activity in the Mn-like group of cambialistic superoxide dismutases Rsc Adv, 5, 2015
4OS7	Crystal structure of urokinase-type plasminogen activator (uPA) complexed with bicyclic peptide UK607 (bicyclic) 分子名称: ACETATE ION, GLYCEROL, SULFATE ION, ... 著者 Chen, S, Pojer, F, Heinis, C. 登録日 2014-02-12 公開日 2014-09-24 最終更新日 2021-06-02 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides. Nat Chem, 6, 2014
4YJO	THE KINASE DOMAIN OF HUMAN SPLEEN TYROSINE (SYK) IN COMPLEX WITH GTC000222 分子名称: 5-chloro-N~2~-(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)-N~4~-ethyl-N~4~-(1H-indazol-4-yl)pyrimidine-2,4-diamine, GLYCEROL, Tyrosine-protein kinase SYK 著者 Somers, D.O, Neu, M. 登録日 2015-03-03 公開日 2015-09-30 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor. Bioorg. Med. Chem. Lett., 21, 2011
4OH7	Crystal structure of Ornithine carbamoyltransferase from Brucella melitensis 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Ornithine carbamoyltransferase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-01-17 公開日 2014-02-26 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of Ornithine carbamoyltransferase from Brucella melitensis To be Published
4YU2	Crystal structure of DYRK1A with harmine-derivatized AnnH-75 inhibitor 分子名称: (1-chloro-7-methoxy-9H-beta-carbolin-9-yl)acetonitrile, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, SULFATE ION, ... 著者 Chaikuad, A, Wurzlbauer, A, Nowak, R, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bracher, F, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2015-03-18 公開日 2015-03-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition-The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine. Molecules, 25, 2020
4OHM	Human GKRP bound to AMG-0771 and sorbitol-6-phosphate 分子名称: (2S)-2-{4-[(2S)-4-[(6-aminopyridin-3-yl)sulfonyl]-2-(prop-1-yn-1-yl)piperazin-1-yl]phenyl}-3,3,3-trifluoropropane-1,2-diol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ... 著者 Jordan, S.R, Chmait, S. 登録日 2014-01-17 公開日 2014-07-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 3. Structure-activity relationships within the aryl carbinol region of the N-arylsulfonamido-N'-arylpiperazine series. J.Med.Chem., 57, 2014
4YK6	Crystal structure of APC-ARM in complexed with Amer1-A4 分子名称: APC membrane recruitment protein 1, Adenomatous polyposis coli protein 著者 Zhang, Z, Xiao, Y, Wu, G. 登録日 2015-03-04 公開日 2016-03-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners Cell Discov, 1, 2015
4OV4	Isopropylmalate synthase binding with ketoisovalerate 分子名称: 2-isopropylmalate synthase, 3-METHYL-2-OXOBUTANOIC ACID, ZINC ION 著者 Zhang, Z, Wu, J, Wang, C, Zhang, P. 登録日 2014-02-20 公開日 2014-08-20 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Subdomain II of alpha-isopropylmalate synthase is essential for activity: inferring a mechanism of feedback inhibition. J.Biol.Chem., 289, 2014
4OVI	Phenylacetone monooxygenase: oxidised enzyme in complex with APADP 分子名称: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, ACETATE ION, CHLORIDE ION, ... 著者 Martinoli, C, Fraaije, M.W, Mattevi, A. 登録日 2013-09-19 公開日 2014-05-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Beyond the Protein Matrix: Probing Cofactor Variants in a Baeyer-Villiger Oxygenation Reaction. Acs Catalysis, 3, 2013
4YL3	Crystal Structures of mPGES-1 Inhibitor Complexes 分子名称: 5-[4-bromo-2-(2-chloro-6-fluorophenyl)-1H-imidazol-5-yl]-2-{[4-(trifluoromethyl)phenyl]ethynyl}pyridine, GLUTATHIONE, Prostaglandin E synthase, ... 著者 Luz, J.G, Antonysamy, S, Kuklish, S.L, Fisher, M.J. 登録日 2015-03-04 公開日 2015-07-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Crystal Structures of mPGES-1 Inhibitor Complexes Form a Basis for the Rational Design of Potent Analgesic and Anti-Inflammatory Therapeutics. J.Med.Chem., 58, 2015
4O6P	Structural and functional studies the characterization of C58G/C70G mutant in Cys4 Zinc-finger motif in the recombination mediator protein RecR 分子名称: Recombination protein RecR, ZINC ION 著者 Tang, Q, Liu, Y.P, Yan, X.X, Liang, D.C. 登録日 2013-12-23 公開日 2014-12-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural and functional characterization of Cys4 zinc finger motif in the recombination mediator protein RecR. DNA Repair (Amst.), 24, 2014
4OJL	Crystal Structure of Putative Tailspike Protein (TSP1, orf210) from Escherichia coli O157:H7 Bacteriohage CBA120 in Complex with Glucose 分子名称: Tailspike protein, ZINC ION, beta-D-glucopyranose 著者 Chen, C, Herzberg, O. 登録日 2014-01-21 公開日 2014-03-26 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of ORF210 from E. coli O157:H1 phage CBA120 (TSP1), a putative tailspike protein. Plos One, 9, 2014
4OIU	Crystal structure of T877A-AR-LBD bound with co-regulator peptide 分子名称: Androgen receptor, HYDROXYFLUTAMIDE, co-regulator peptide 著者 Liu, J.S, Hsu, C.L, Wu, W.G. 登録日 2014-01-20 公開日 2014-08-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
4YSE	High resolution synchrotron structure of copper nitrite reductase from Alcaligenes faecalis 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETIC ACID, COPPER (II) ION, ... 著者 Fukuda, Y, Tse, K.M, Suzuki, M, Diederichs, K, Hirata, K, Nakane, T, Sugahara, M, Nango, E, Tono, K, Joti, Y, Kameshima, T, Song, C, Hatsui, T, Yabashi, M, Nureki, O, Matsumura, H, Inoue, T, Iwata, S, Mizohata, E. 登録日 2015-03-17 公開日 2016-03-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Redox-coupled proton transfer mechanism in nitrite reductase revealed by femtosecond crystallography Proc.Natl.Acad.Sci.USA, 113, 2016
4OJ1	Crystal structure of truncated Acylphosphatase from S. sulfataricus 分子名称: Acylphosphatase, CHLORIDE ION, SODIUM ION 著者 Dilovic, I, Bolognesi, M, Ricagno, S. 登録日 2014-01-20 公開日 2014-02-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of truncated Acylphosphatase from S. sulfataricus TO BE PUBLISHED

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