PDB: 8861 件ウェブページステータス検索Chemie searchBIRD

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4EDV	The structure of the S. aureus DnaG RNA Polymerase Domain bound to pppGpp and Manganese 分子名称: BENZAMIDINE, DNA primase, MANGANESE (II) ION, ... 著者 Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M. 登録日 2012-03-27 公開日 2012-07-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases. Structure, 20, 2012
4EDK	The structure of the S. aureus DnaG RNA Polymerase Domain bound to GTP and Manganese 分子名称: BENZAMIDINE, DNA primase, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M. 登録日 2012-03-27 公開日 2012-07-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases. Structure, 20, 2012
6HVO	Crystal structure of human PCNA in complex with three peptides of p12 subunit of human polymerase delta 分子名称: DNA polymerase delta subunit 4, Proliferating cell nuclear antigen, SULFATE ION 著者 Gonzalez-Magana, A, Romano-Moreno, M, Rojas, A.L, Blanco, F.J, De Biasio, A. 登録日 2018-10-11 公開日 2019-01-23 最終更新日 2019-03-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The p12 subunit of human polymerase delta uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA). J.Biol.Chem., 294, 2019
4EDG	The structure of the S. aureus DnaG RNA Polymerase Domain bound to ATP and Manganese 分子名称: ADENOSINE-5'-TRIPHOSPHATE, BENZAMIDINE, DNA primase, ... 著者 Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M. 登録日 2012-03-27 公開日 2012-07-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.003 Å) 主引用文献 Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases. Structure, 20, 2012
4EE1	The structure of the S. aureus DnaG RNA Polymerase Domain bound to CTP and Manganese 分子名称: BENZAMIDINE, CYTIDINE-5'-TRIPHOSPHATE, DNA primase, ... 著者 Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M. 登録日 2012-03-28 公開日 2012-07-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases. Structure, 20, 2012
7QHL	Crystal structure of Cyclin-dependent kinase 2/cyclin A in complex with 3,5,7-Substituted pyrazolo[4,3-d]pyrimidine inhibitor 24 分子名称: 1,2-ETHANEDIOL, 5-(2-amino-1-ethyl)thio-3-cyclobutyl-7-[4-(pyrazol-1-yl)benzyl]amino-1(2)H-pyrazolo[4,3-d]pyrimidine, Cyclin-A2, ... 著者 Djukic, S, Skerlova, J, Rezacova, P. 登録日 2021-12-13 公開日 2022-07-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 3,5,7-Substituted Pyrazolo[4,3- d ]Pyrimidine Inhibitors of Cyclin-Dependent Kinases and Cyclin K Degraders. J.Med.Chem., 65, 2022
3AX1	Molecular insights into miRNA processing by Arabidopsis Serrate 分子名称: Serrate RNA effector molecule, ZINC ION 著者 Yuan, Y.A, Machida, S, Chen, H.Y. 登録日 2011-03-28 公開日 2011-07-13 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Molecular insights into miRNA processing by Arabidopsis thaliana SERRATE Nucleic Acids Res., 39, 2011
3MMY	Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nuclear pore complex protein Nup98, mRNA export factor 著者 Hoelz, A, Ren, Y. 登録日 2010-04-20 公開日 2010-06-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1. Proc.Natl.Acad.Sci.USA, 107, 2010
3S24	Crystal structure of human mRNA guanylyltransferase 分子名称: SULFATE ION, mRNA-capping enzyme 著者 Das, K, Chu, C, Thyminski, J.R, Bauman, J.D, Guan, R, Qiu, W, Montelione, G.T, Arnold, E, Shatkin, A.J. 登録日 2011-05-16 公開日 2011-06-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.0137 Å) 主引用文献 Structure of the guanylyltransferase domain of human mRNA capping enzyme. Proc.Natl.Acad.Sci.USA, 108, 2011
1ENW	ELONGATION FACTOR TFIIS DOMAIN II 分子名称: TRANSCRIPTION ELONGATION FACTOR S-II 著者 Morin, P.E, Awrey, D.E, Edwards, A.M, Arrowsmith, C.H. 登録日 2000-03-21 公開日 2000-04-12 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Elongation factor TFIIS contains three structural domains: solution structure of domain II. Proc.Natl.Acad.Sci.USA, 93, 1996
1XJR	The Structure of a Rigorously Conserved RNA Element Within the SARS Virus Genome 分子名称: MAGNESIUM ION, s2m RNA 著者 Robertson, M.P, Igel, H, Baertsch, R, Haussler, D, Ares Jr, M, Scott, W.G. 登録日 2004-09-24 公開日 2005-02-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The structure of a rigorously conserved RNA element within the SARS virus genome Plos Biol., 3, 2005
3HYF	Crystal structure of HIV-1 RNase H p15 with engineered E. coli loop and active site inhibitor 分子名称: 2-(3,4-dichlorobenzyl)-5,6-dihydroxypyrimidine-4-carboxylic acid, ACETATE ION, GLYCEROL, ... 著者 Lansdon, E.B, Kirschberg, T.A. 登録日 2009-06-22 公開日 2009-10-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information. J.Med.Chem., 52, 2009
7E15	Protein ternary complex working for DNA replication initiation 分子名称: DNA polymerase II small subunit, Gins51, SsDNA-specific exonuclease 著者 Oyama, T, Ishino, Y. 登録日 2021-01-30 公開日 2021-10-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Family D DNA polymerase interacts with GINS to promote CMG-helicase in the archaeal replisome. Nucleic Acids Res., 50, 2022
5BKH	The splicing activity and an alternative domain-swapped structure of the Pyrococcus horikoshii PolII mini-intein 分子名称: DNA polymerase II large subunit 著者 Li, Z, Li, H. 登録日 2021-03-19 公開日 2021-08-11 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 An alternative domain-swapped structure of the Pyrococcus horikoshii PolII mini-intein. Sci Rep, 11, 2021
5FLX	Mammalian 40S HCV-IRES complex 分子名称: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ... 著者 Yamamoto, H, Collier, M, Loerke, J, Ismer, J, Schmidt, A, Hilal, T, Sprink, T, Yamamoto, K, Mielke, T, Burger, J, Shaikh, T.R, Dabrowski, M, Hildebrand, P.W, Scheerer, P, Spahn, C.M.T. 登録日 2015-10-28 公開日 2015-12-23 最終更新日 2017-08-30 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA. Embo J., 34, 2015
7OM6	Thosea asigna virus RdRP domain in complex with RNA 分子名称: DI(HYDROXYETHYL)ETHER, RNA (5'-R(P*AP*AP*AP*UP*UP*U)-3'), RNA-dependent RNA polymerase 著者 Ferrero, D.S, Falqui, M, Verdaguer, N. 登録日 2021-05-21 公開日 2021-07-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Snapshots of a Non-Canonical RdRP in Action. Viruses, 13, 2021
7Q2J	Quaternary Complex of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC Homer 分子名称: Elongin-B, Elongin-C, N-[5-[4-[[5-[[(2S)-3,3-dimethyl-1-[(2S,4R)-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]-4-oxidanyl-pyrrolidin-1-yl]-1-oxidanylidene-butan-2-yl]amino]-5-oxidanylidene-pentyl]carbamoyl]phenyl]-2-(4-methylpiperazin-1-yl)phenyl]-6-oxidanylidene-4-(trifluoromethyl)-1H-pyridine-3-carboxamide, ... 著者 Kraemer, A, Doelle, A, Schwalm, M.P, Adhikari, B, Wolf, E, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2021-10-25 公開日 2021-11-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization. Cell Chem Biol, 30, 2023
7KI3	Human Argonaute2:miR-122 bound to the HCV genotype 1a site-1 RNA 分子名称: BARIUM ION, HCV genotype 1a miR-122 site-1, Protein argonaute-2, ... 著者 Gebert, L.F.R, MacRae, I.J. 登録日 2020-10-22 公開日 2021-10-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A structured RNA motif locks Argonaute2:miR-122 onto the 5' end of the HCV genome. Nat Commun, 12, 2021
8G6R	Porcine epidemic diarrhea virus core polymerase complex 分子名称: RNA (5'-R(P*AP*AP*GP*AP*AP*GP*CP*UP*AP*UP*UP*AP*AP*AP*AP*UP*CP*AP*CP*A)-3'), RNA (5'-R(P*GP*GP*UP*UP*GP*UP*GP*AP*UP*UP*UP*UP*AP*AP*UP*AP*GP*CP*UP*U)-3'), ZINC ION, ... 著者 Anderson, T.K, Kirchdoerfer, R.N. 登録日 2023-02-15 公開日 2023-03-29 最終更新日 2023-10-04 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 An alphacoronavirus polymerase structure reveals conserved co-factor functions. Biorxiv, 2023
6N4O	Human Argonaute2-miR-122 bound to a seed and supplementary paired target 分子名称: Protein argonaute-2, RNA (5'-R(*CP*CP*AP*UP*UP*GP*UP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3') 著者 Sheu-Gruttadauria, J, MacRae, I.J. 登録日 2018-11-19 公開日 2019-05-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.899 Å) 主引用文献 Beyond the seed: structural basis for supplementary microRNA targeting by human Argonaute2. Embo J., 38, 2019
8URB	Porcine epidemic diarrhea virus complete core polymerase complex 分子名称: RNA (33-MER), RNA (55-MER), ZINC ION, ... 著者 Anderson, T.K, Kirchdoerfer, R.N. 登録日 2023-10-25 公開日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 An alphacoronavirus polymerase structure reveals conserved co-factor functions. Biorxiv, 2023
3W1K	Crystal structure of the selenocysteine synthase SelA and tRNASec complex 分子名称: L-seryl-tRNA(Sec) selenium transferase, selenocysteine tRNA 著者 Itoh, Y, Sekine, S, Yokoyama, S. 登録日 2012-11-15 公開日 2013-06-05 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (7.5 Å) 主引用文献 Decameric SelA-tRNA(Sec) ring structure reveals mechanism of bacterial selenocysteine formation Science, 340, 2013
4GHA	Crystal structure of Marburg virus VP35 RNA binding domain bound to 12-bp dsRNA 分子名称: Polymerase cofactor VP35, RNA (5'-R(*CP*UP*AP*GP*AP*CP*GP*UP*CP*UP*AP*G)-3') 著者 Bale, S, Jean-Philippe, J, Bornholdt, Z.A, Kimberlin, C.K, Halfmann, P, Zandonatti, M.A, Kunert, J, Kroon, G.J.A, Kawaoka, Y, MacRae, I.J, Wilson, I.A, Saphire, E.O. 登録日 2012-08-07 公開日 2012-08-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism. Plos Pathog., 8, 2012
3ISD	Ternary complex of human DNA polymerase beta with an abasic site (THF): DAPCPP mismatch 分子名称: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine, 5'-D(*CP*CP*GP*AP*CP*(3DR)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', ... 著者 Beard, W.A, Shock, D.D, Batra, V.K, Pedersen, L.C, Wilson, S.H. 登録日 2009-08-25 公開日 2009-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 DNA polymerase beta substrate specificity: side chain modulation of the "A-rule". J.Biol.Chem., 284, 2009
5ZYQ	The Structure of Human PAF1/CTR9 complex 分子名称: RNA polymerase-associated protein CTR9 homolog,RNA polymerase II-associated factor 1 homolog 著者 Xie, Y, Zheng, M, Zhou, H, Long, J. 登録日 2018-05-28 公開日 2018-09-26 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.531 Å) 主引用文献 Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation. Nat Commun, 9, 2018

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