8UQL
 
 | | Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH in loaded state, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | | 登録日 | 2023-10-24 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis of RfaH-mediated transcription-translation coupling.
Nat.Struct.Mol.Biol., 2024
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8UQP
 | | Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | | 登録日 | 2023-10-24 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural basis of RfaH-mediated transcription-translation coupling.
Nat.Struct.Mol.Biol., 2024
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7DV6
 | | Discovery of Functionally Selective Transforming Growth Factor beta Type II Receptor (TGF-beta RII) Inhibitors as Anti-Fibrosis Agents | | 分子名称: | 5-[(3S)-5,5-dimethyloxolan-3-yl]-6-methoxy-3-(2-methoxypyridin-4-yl)pyrazolo[1,5-a]pyrimidine, TGF-beta receptor type-2 | | 著者 | Nishihata, J, Nomura, A, Miwa, S, Doi, S, Adachi, T. | | 登録日 | 2021-01-12 | | 公開日 | 2021-06-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Discovery of Selective Transforming Growth Factor beta Type II Receptor Inhibitors as Antifibrosis Agents.
Acs Med.Chem.Lett., 12, 2021
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8UR0
 | | Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, NusA, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | | 登録日 | 2023-10-25 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis of RfaH-mediated transcription-translation coupling.
Nat.Struct.Mol.Biol., 2024
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1FA9
 | | HUMAN LIVER GLYCOGEN PHOSPHORYLASE A COMPLEXED WITH AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE, LIVER FORM, ... | | 著者 | Rath, V.L, Ammirati, M, LeMotte, P.K, Fennell, K.F, Mansour, M.N, Danley, D.E, Hynes, T.R, Schulte, G.K, Wasilko, D.J, Pandit, J. | | 登録日 | 2000-07-12 | | 公開日 | 2000-08-25 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core.
Mol.Cell, 6, 2000
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8ITM
 | | Cryo-EM structure of GIPR splice variant 2 (SV2) in complex with Gs protein | | 分子名称: | Gastric inhibitory polypeptide receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Zhao, F.H, Hang, K.N, Zhou, Q.T, Shao, L.J, Li, H, Li, W.Z, Lin, S, Dai, A.T, Cai, X.Q, Liu, Y.Y, Xu, Y.N, Feng, W.B, Yang, D.H, Wang, M.W. | | 登録日 | 2023-03-22 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Molecular basis of signal transduction mediated by the human GIPR splice variants.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8ITL
 | | Cryo-EM structure of GIPR splice variant 1 (SV1) in complex with Gs protein | | 分子名称: | Gastric inhibitory polypeptide receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Zhao, F.H, Hang, K.N, Zhou, Q.T, Shao, L.J, Li, H, Li, W.Z, Lin, S, Dai, A.T, Cai, X.Q, Liu, Y.Y, Xu, Y.N, Feng, W.B, Yang, D.H, Wang, M.W. | | 登録日 | 2023-03-22 | | 公開日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | Molecular basis of signal transduction mediated by the human GIPR splice variants.
Proc.Natl.Acad.Sci.USA, 120, 2023
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1FIT
 | | FHIT (FRAGILE HISTIDINE TRIAD PROTEIN) | | 分子名称: | FRAGILE HISTIDINE PROTEIN, SULFATE ION, beta-D-fructofuranose | | 著者 | Lima, C.D, D'Amico, K.L, Naday, I, Rosenbaum, G, Westbrook, E.M, Hendrickson, W.A. | | 登録日 | 1997-05-17 | | 公開日 | 1997-11-19 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | MAD analysis of FHIT, a putative human tumor suppressor from the HIT protein family.
Structure, 5, 1997
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1F6B
 | | CRYSTAL STRUCTURE OF SAR1-GDP COMPLEX | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SAR1, ... | | 著者 | Huang, M, Wilson, I.A, Balch, W.E. | | 登録日 | 2000-06-21 | | 公開日 | 2002-01-09 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of Sar1-GDP at 1.7 A resolution and the role of the NH2 terminus in ER export.
J.Cell Biol., 155, 2001
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2RFX
 | | Crystal Structure of HLA-B*5701, presenting the self peptide, LSSPVTKSF | | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | 著者 | Archbold, J.K, Macdonald, W.A, Rossjohn, J, McCluskey, J. | | 登録日 | 2007-10-02 | | 公開日 | 2008-07-08 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity
Immunity, 28, 2008
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1FQM
 | | X-RAY CRYSTAL STRUCTURE OF ZINC-BOUND F93I/F95M/W97V CARBONIC ANHYDRASE (CAII) VARIANT | | 分子名称: | CARBONIC ANHYDRASE, MERCURY (II) ION, ZINC ION | | 著者 | Cox, J.D, Hunt, J.A, Compher, K.M, Fierke, C.A, Christianson, D.W. | | 登録日 | 2000-09-06 | | 公開日 | 2001-01-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II.
Biochemistry, 39, 2000
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2VNE
 | | The X-ray structure of Norcoclaurine synthase from Thalictrum flavum | | 分子名称: | S-NORCOCLAURINE SYNTHASE | | 著者 | Ilari, A, Franceschini, S, Boffi, A, Bonamore, A, Pasquo, A. | | 登録日 | 2008-02-04 | | 公開日 | 2008-08-05 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Structural Basis of Enzymatic S-Norcoclaurine Biosynthesis.
J.Biol.Chem., 284, 2009
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1VGK
 | | The crystal structure of class I Major histocompatibility complex, H-2Kd at 2.0 A resolution | | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-D alpha chain, ... | | 著者 | Zhou, M, Xu, Y, Liu, Y, Gao, G.F, Tien, P, Rao, Z. | | 登録日 | 2004-04-27 | | 公開日 | 2005-06-28 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | The crystal structure of class I major histocompatibility complex, H-2Kd at 2.0 A resolution
To be Published
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1FEA
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1VQ6
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2VGC
 | | GAMMA-CHYMOTRYPSIN D-PARA-CHLORO-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX | | 分子名称: | D-1-(4-CHLOROPHENYL)-2-(ACETAMIDO)ETHANE BORONIC ACID, GAMMA CHYMOTRYPSIN, SULFATE ION | | 著者 | Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F. | | 登録日 | 1997-05-01 | | 公開日 | 1997-11-12 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
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6LQP
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1FIA
 | | CRYSTAL STRUCTURE OF THE FACTOR FOR INVERSION STIMULATION FIS AT 2.0 ANGSTROMS RESOLUTION | | 分子名称: | FACTOR FOR INVERSION STIMULATION (FIS) | | 著者 | Kostrewa, D, Granzin, J, Choe, H.-W, Labahn, J, Saenger, W. | | 登録日 | 1991-12-18 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the factor for inversion stimulation FIS at 2.0 A resolution.
J.Mol.Biol., 226, 1992
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1VQ5
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1FO5
 | | SOLUTION STRUCTURE OF REDUCED MJ0307 | | 分子名称: | THIOREDOXIN | | 著者 | Cave, J.W, Cho, H.S, Batchelder, A.M, Kim, R, Yokota, H, Wemmer, D.E, Berkeley Structural Genomics Center (BSGC) | | 登録日 | 2000-08-24 | | 公開日 | 2001-04-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution nuclear magnetic resonance structure of a protein disulfide oxidoreductase from Methanococcus jannaschii.
Protein Sci., 10, 2001
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1FQN
 | | X-RAY CRYSTAL STRUCTURE OF METAL-FREE F93I/F95M/W97V CARBONIC ANHYDRASE (CAII) VARIANT | | 分子名称: | CARBONIC ANHYDRASE | | 著者 | Cox, J.D, Hunt, J.A, Compher, K.M, Fierke, C.A, Christianson, D.W. | | 登録日 | 2000-09-06 | | 公開日 | 2001-01-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II.
Biochemistry, 39, 2000
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1FT8
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8POS
 | | Crystal structure of wolbachia leucyl-tRNA synthetase editing domain bound to cmpd9-AMP adduct | | 分子名称: | Leucine--tRNA ligase, SULFATE ION, [(1R,3'S,5S,6R,8R)-3'-(aminomethyl)-8-(6-aminopurin-9-yl)-4'-bromanyl-7'-[3-[methyl-(phenylmethyl)amino]propoxy]spiro[2,4,7-trioxa-3$l^{4}-borabicyclo[3.3.0]octane-3,1'-3H-2,1$l^{4}-benzoxaborole]-6-yl]methyl dihydrogen phosphate | | 著者 | Palencia, A, Hoffmann, G. | | 登録日 | 2023-07-05 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.137 Å) | | 主引用文献 | Targeting a microbiota Wolbachian aminoacyl-tRNA synthetase to block its pathogenic host.
Sci Adv, 10, 2024
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2PGR
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1FQ0
 | | KDPG ALDOLASE FROM ESCHERICHIA COLI | | 分子名称: | CITRIC ACID, KDPG ALDOLASE | | 著者 | Naismith, J.H. | | 登録日 | 2000-09-01 | | 公開日 | 2000-10-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli.
Structure, 9, 2001
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